QIOU GU, TIAN ZHAN, XIAO GUAN, CHUILIN LAI, NA LU, GUOGUANG WANG, LEI XU, XIANG GAO, JIANPING ZHANG*
Oncology Research, Vol.31, No.3, pp. 287-297, 2023, DOI:10.32604/or.2023.028124
- 22 May 2023
Abstract Background: Gastric cancer (GC) is a malignancy with the worst prognosis that seriously threatens human
health, especially in East Asia. Apolipoprotein C1 (apoc1) belongs to the apolipoprotein family. In addition, apoc1 has
been associated with various tumors. However, its role in GC remains unclear. Methods: Firstly, we quantified its
expression in GC and adjacent tumor tissues, using The Cancer Genome Atlas (TCGA). Next, we assessed cell
invasion and migration abilities. Finally, we revealed the role of apoc1 in the tumor microenvironment (TME),
immune cell infiltration and drug sensitivity. Results: Firstly, in TCGA database, it has been shown that… More >
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