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    ARTICLE

    Meta-analysis evaluation of the treatment of neonatal hypoxic– ischemic encephalopathy with ganglioside

    Wen LI, Junli YANG, Dong ZHOU, Jinghui ZHANG, Qingcui ZHUO

    BIOCELL, Vol.43, No.1, pp. 7-12, 2019, DOI:10.32604/biocell.2019.04763

    Abstract The efficacy and safety of ganglioside in the treatment of neonates who suffer from hypoxic–ischemic encephalopathy (HIE) needs to be fully evaluated. We searched the following databases: PubMed, ScienceDirect, LISTA, CNKI, Chinese biomedical literature database and Wanfang digital journals of full-text database to determine the inclusion and exclusion criteria of papers and a total of 12 papers were included after quality evaluation. Then we conducted the meta-analysis with RevMan5.0 software. The results showed that compared with the control group, the abnormal rate declined in the ganglioside-treated group (relative risk (RR)=0.27, 95% confidence interval (CI)= 0.05– More >

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