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  • Open Access

    ARTICLE

    Mechanistic Scale-Up of Gas-Solid Fluidized Beds via Local Hydrodynamic Similarity

    Faraj M. Zaid1,2, Thaar M. Aljuwaya3,4,*, Muthanna H. Al-Dahhan1,3,5,*

    FDMP-Fluid Dynamics & Materials Processing, Vol.21, No.10, pp. 2443-2471, 2025, DOI:10.32604/fdmp.2025.067557 - 30 October 2025

    Abstract This study presents a detailed experimental evaluation of a newly developed mechanistic scale-up methodology for gas-solid fluidized beds. Traditional scale-up approaches typically rely on matching global dimensionless groups, which often fail to ensure local hydrodynamic similarity. In contrast, the new mechanistic method aims to achieve scale-up by matching the radial profiles of gas holdup between geometrically similar beds at corresponding dimensionless axial positions (z/Dc). This approach is based on the premise that when gas holdup profiles align, other key hydrodynamic parameters—such as solids holdup and particle velocity—also become similar. To validate this methodology, experiments were conducted More >

  • Open Access

    ARTICLE

    Gamma Irradiation Upregulates B-cell Translocation Gene 2 to Attenuate Cell Proliferation of Lung Cancer Cells Through the JNK and NF-κB Pathways

    Peihe Wang*, Yuanyuan Cai*, Dongju Lin, Yingxiao Jiang*

    Oncology Research, Vol.25, No.7, pp. 1199-1205, 2017, DOI:10.3727/096504017X14873444858101

    Abstract Gamma ray can promote cancer cell apoptosis and cell cycle arrest. It is often used in the clinical treatment of tumors, including lung cancer. In this study, we aimed to explore the role of gamma ray treatment and its correlation with BTG2 in cell proliferation, apoptosis, and cell cycle arrest regulation in a lung cancer cell line. A549 cell viability, apoptosis rate, and cell cycle were investigated after gamma ray treatment. We then used siRNA for BTG2 to detect the effect of BTG2 knockdown on the progress of gamma ray-treated lung cancer cells. Finally, we… More >

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