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  • Open Access

    ARTICLE

    Synergistic Effects of Melatonin and Methyl Jasmonate in Mitigating Drought-Induced Oxidative Stress in Common Bean (Phaseolus vulgaris)

    Totan Kumar Ghosh1, Md. Roushonuzzaman Rakib1, Munna1, S. M. Zubair AL-Meraj1, Md. Moshiul Islam2, Anika Nazran1, Mohammad Golam Mostofa3,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 3925-3943, 2025, DOI:10.32604/phyton.2025.073382 - 29 December 2025

    Abstract The productivity of common bean (Phaseolus vulgaris L.), an economically important legume, is severely hindered by drought stress. While melatonin (Mel) and methyl jasmonate (MeJA) are known to alleviate abiotic stresses, their combined effects in mitigating drought-induced oxidative stress are unknown. Here, we examined the synergistic effects of Mel and MeJA in alleviating drought-associated oxidative damage in common bean. Compared with well-watered controls, drought stress caused a significant decline in plant biomass, photosynthetic pigments, and photosystem II efficiency (Fv/Fm). Drought also significantly increased hydrogen peroxide (H2O2) accumulation, which likely contributed to membrane lipid peroxidation, as indicated by… More >

  • Open Access

    ARTICLE

    Construction of Synergistic and Efficient Flame-Retardant Polyamide 6 Composites by Incorporating Aluminum Diethylphosphinate and Fly Ash

    Ruiping Wang, Chuang He, Shuo Zhang, Miaojun Xu*, Zhuo Wang, Xiaoli Li*, Bin Tao, Suliang Gao, Bin Li*

    Journal of Polymer Materials, Vol.42, No.4, pp. 1035-1049, 2025, DOI:10.32604/jpm.2025.073108 - 26 December 2025

    Abstract The fabrication of highly flame-retardant polyamide 6 (PA6) composites is of great significance for expanding their practical applications. Herein, a new flame-retardant system (ADP/FA) was developed by combining aluminum diethylphosphinate (ADP) with excellent flame retardancy and fly ash (FA), an economical and environmentally friendly industrial waste. Due to the synergistic flame-retardant effect of ADP/FA in the condensed phase and gas phase, the PA6 composite containing only 11 wt% of ADP/FA (mass ratio 93:7) obtained vertical burning (UL-94) tests V-0 rating with a limiting oxygen index (LOI) of 30.9%. To obtain the same flame-retardant level of… More > Graphic Abstract

    Construction of Synergistic and Efficient Flame-Retardant Polyamide 6 Composites by Incorporating Aluminum Diethylphosphinate and Fly Ash

  • Open Access

    ARTICLE

    VCA Augments Doxorubicin Efficacy in Triple-Negative Breast Cancer: Evidence for Multi-Pathway Synergism

    Chang-Eui Hong1,2,3, Su-Yun Lyu1,2,3,*

    BIOCELL, Vol.49, No.12, pp. 2377-2397, 2025, DOI:10.32604/biocell.2025.072360 - 24 December 2025

    Abstract Objective: Triple-negative breast cancer (TNBC) remains a major therapeutic challenge with limited treatment options and poor prognosis. This study aimed to investigate the synergistic anticancer effects of doxorubicin (DOX) combined with Viscum album L. var. coloratum agglutinin (VCA) and to elucidate the underlying molecular mechanisms in TNBC cells. Methods: This study evaluated the synergistic effects and mechanisms of doxorubicin (DOX) and Viscum album L. var. coloratum agglutinin (VCA) combination in MDA-MB231 TNBC cells. Cell viability, oxidative stress markers, apoptosis-related proteins, cell migration, and proliferative recovery were assessed using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, superoxide dismutase (SOD) and nitric oxide… More >

  • Open Access

    ARTICLE

    Landslide Susceptibility Assessment Using Analytical Hierarchy Process (AHP) in Hulu Selangor

    Izzah Liyanamadihah Ibrahim1, Nurhanisah Hashim1,*, Ainon Nisa Othman1,*, Noorfatekah Talib2, Sarah Shaharuddin3

    Revue Internationale de Géomatique, Vol.34, pp. 915-937, 2025, DOI:10.32604/rig.2025.072321 - 09 December 2025

    Abstract This study aims to assess landslide susceptibility in Hulu Selangor, Selangor, Malaysia, an area that is exposed to rapid industrial and infrastructural growth. Six conditioning factors, such as slope, land use, lithology, road proximity, and river proximity, were integrated through the Analytic Hierarchy Process (AHP) in a GIS environment. The weights distribution analysis revealed slope (40.50%) and lithology (23.12%) as the most important factors, followed by river proximity (15.09%) and road proximity (13.76%). The developed susceptibility map was divided into five zones: very low (12.4%), low (18.7%), medium (35.6%), high (22.1%), and very high (11.2%).… More >

  • Open Access

    ARTICLE

    Spatial Analysis Tool for Urban Environmental Quality Assessment: Leveraging Geoinformatics and GIS

    Igor Musikhin*

    Revue Internationale de Géomatique, Vol.34, pp. 939-957, 2025, DOI:10.32604/rig.2025.071168 - 09 December 2025

    Abstract Urban environmental quality research is crucial, as cities become competitive centers concentrating human talent, industrial activity, and financial resources, contributing significantly to national economies. Municipal and government priorities include retaining residents, preventing skilled worker outflow, and meeting the evolving needs of urban populations. The study presents the development and application of a scenario-based spatial analysis tool for assessing urban environmental quality at a detailed spatial scale within the city of Novosibirsk. Using advanced geoinformatics, GIS techniques, and an expert knowledge base, the tool integrates diverse thematic data layers with user-defined scenarios to compute and visualize… More >

  • Open Access

    ARTICLE

    Synergistic Regulation of Light Intensity and Calcium Nutrition in PFAL-Grown Lettuce by Optimizing Morphogenesis and Nutrient Homeostasis

    Jie Jin1, Tianci Wang1, Yaning Wang1, Jingqi Yao2, Jinxiu Song1,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.11, pp. 3611-3632, 2025, DOI:10.32604/phyton.2025.070680 - 01 December 2025

    Abstract In plant factory with artificial lighting, precise regulation of environmental and nutritional factors is essential to optimize both growth and quality of leafy vegetables. This study systematically evaluated the combined effects of light intensity (150, 200, 250 μmol/(m2·s)) and calcium supply in the nutrient solution (0.5, 1.0, 1.5 mmol/L) on lettuce morphology, photosynthesis, quality indices, and tipburn incidence. Elevating light from 150 to 200 μmol/(m2·s) significantly enhanced leaf number, area, photosynthetic rate, biomass, and foliar calcium. These gains plateaued at 250 μmol/(m2·s), where tipburn incidence surged to 76.5%. Photosynthetic pigments progressively rose with light intensity. Calcium supply… More >

  • Open Access

    ARTICLE

    Using Hate Speech Detection Techniques to Prevent Violence and Foster Community Safety

    Ayaz Hussain1, Asad Hayat2, Muhammad Hasnain1,*

    Journal on Artificial Intelligence, Vol.7, pp. 485-498, 2025, DOI:10.32604/jai.2025.071933 - 17 November 2025

    Abstract Violent hate speech and scapegoating people against one another have emerged as a rising worldwide issue. But identifying and combating such content is crucial to create safer and more inclusive societies. The current study conducted research using Machine Learning models to classify hate speech and overcome the limitations posed in the existing detection techniques. Logistic Regression (LR), Random Forest (RF), K-Nearest Neighbour (KNN) and Decision Tree were used on top of a publicly available hate speech dataset. The data was preprocessed by cleaning the text and tokenization and using normalization techniques to efficiently train the… More >

  • Open Access

    ARTICLE

    Spatio-Temporal Flood Inundation Dynamics and Land Use Transformation in the Jhelum River Basin Using Remote Sensing and Historical Hydrological Data

    Ihsan Qadir1, Usama Naeem2, Ahmed Nouman3, Aamir Raza4, Jun Wu1,*

    Revue Internationale de Géomatique, Vol.34, pp. 831-853, 2025, DOI:10.32604/rig.2025.069020 - 10 November 2025

    Abstract The Jhelum River Basin in Pakistan has experienced recurrent and severe flooding over the past several decades, leading to substantial economic losses, infrastructure damage, and socio-environmental disruptions. This study uses multi-temporal satellite remote sensing data with historical hydrological records to map the spatial and temporal dynamics of major flood events occurring between 1988 and 2019. By utilizing satellite imagery from Landsat 5, Landsat 8, and Sentinel-2, key flood events were analyzed through the application of water indices such as the Normalized Difference Water Index (NDWI) and the Modified NDWI (MNDWI) to delineate flood extents. Historical… More >

  • Open Access

    ARTICLE

    Associations of systemic immune-inflammation index, product of platelet, and neutrophil count, with the pathological grade of bladder cancer

    Lihao Zhang1,2, Lin Cao1,2, Lige Huang1,2, Jie Wang1,2, Jiabing Li2,3,*

    Canadian Journal of Urology, Vol.32, No.5, pp. 457-468, 2025, DOI:10.32604/cju.2025.067364 - 30 October 2025

    Abstract Background: Studies have indicated an association between inflammatory factors (IFs) in the blood and the development of bladder cancer (BC). This study aimed to explore the correlation and clinical significance of IFs with the pathological grading of BC. Methods: A retrospective analysis was conducted on the preoperative blood routine results, postoperative pathological findings, and baseline information of 163 patients. Patients were divided into high-grade and low-grade groups based on pathological grading. Group comparisons and logistic regression analyses were performed using R software version 4.1.3 to explore the relationships between IFs and BC pathological grading. Results: The… More >

  • Open Access

    ARTICLE

    Comprehensive Study of the Effect of Ribs and Cavities on Thermal-Hydraulic Performance of Mini-Channel Heat Sinks

    Shuaimei Lian, Pingping Liu, Wenling Liao*

    Frontiers in Heat and Mass Transfer, Vol.23, No.5, pp. 1395-1415, 2025, DOI:10.32604/fhmt.2025.069454 - 31 October 2025

    Abstract In this work, numerical simulations are performed to investigate the influence of combining ribs and triangular cavities on the thermal-hydraulic performance (THP) of MCHS at fluid velocities ranging from 1 to 4 m/s (corresponding to Reynolds numbers (Re) of 129.75 to 519). Specifically, the ribs are positioned on the bottom wall, and the rib width is equal to the mini-channel width, while the triangular cavities are arranged on the two side walls of the MCHS. By analyzing and comparing key parameters such as velocity distribution, streamline patterns, pressure drop, skin friction coefficient (Cf), Nusselt number (Nu), friction… More >

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