Qi Li, Yifan Wang^*, Yuxi Liu, Xingjing She, Yixuan Wu

CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.1, 2026, DOI:10.32604/cmes.2025.074066 - 29 January 2026

Abstract In data communication, limited communication resources often lead to measurement bias, which adversely affects subsequent system estimation if not effectively handled. This paper proposes a novel bias calibration algorithm under communication constraints to achieve accurate system states of the interested system. An output-based event-triggered scheme is first employed to alleviate transmission burden. Accounting for the limited-communication-induced measurement bias, a novel bias calibration algorithm following the Kalman filtering line is developed to restrain the effect of the measurement bias on system estimation, thereby achieving accurate system state estimates. Subsequently, the Field Programmable Gate Array (FPGA) implementation More >

Woo-Gyun Choi, Byung Joo Kim^*

BIOCELL, Vol.49, No.12, pp. 2365-2375, 2025, DOI:10.32604/biocell.2025.072715 - 24 December 2025

Abstract Objectives: Petasites japonicus (PJ) is a traditional medicinal herb widely used in East Asia for treating diverse ailments. However, its anticancer properties and underlying mechanisms have not been elucidated. This study investigated the anticancer potential and molecular mechanisms of the methanol extract of Petasites japonicus (PJE) in human adenocarcinoma gastric stomach (AGS) cells. Methods: AGS cells were treated with various concentrations of PJE, and cell viability was measured using MTT and CCK-8 assays. Apoptotic cell death was evaluated by the cell cycle, caspase-3 and -9 activity assays, and western blotting. To elucidate the underlying signaling mechanisms, we… More >

Xiaojun Xu^1,#, Hui Lu^2,#, Mengni Du³, Yang Wang^1,4, Mingyan Liu², Lei Qian^1,5, Chunyan Shan¹, Jianan Xu⁶, Yanqiu Yu⁷, Guohua Zhang⁴, Anise M. S. Wu^8,9, Joseph T. F. Lau^1,4,10,*, Deborah Baofeng Wang^1,*

International Journal of Mental Health Promotion, Vol.27, No.10, pp. 1423-1437, 2025, DOI:10.32604/ijmhp.2025.068840 - 31 October 2025

Abstract Background: Adolescent depression and school refusal (SR) are prevalent and important global concerns that need to be understood and addressed. Cross-sectional associations have been reported but prospective relationships between them remain unclear. This longitudinal study investigated the bidirectional relationships between these two problems among Chinese adolescents. Methods: A longitudinal study was conducted in Taizhou, China, surveying students of three junior high schools, three senior high schools, and one vocational high school. A total of 3882 students completed the questionnaire at baseline (T1); 3167 of them completed an identical follow-up questionnaire after 6 months (T2). Depression… More >

Yi-Tzu Chen^1,2,3,#, Shao-Hsuan Kao^4,5,#, Chun-Yi Chuang^6,7, Chun-Wen Su^4,5, Wei-En Yang^4,5, Chih-Hsin Tang^8,9,10, Shun-Fa Yang^4,5,*, Chiao-Wen Lin^2,3,*

Oncology Research, Vol.33, No.11, pp. 3387-3404, 2025, DOI:10.32604/or.2025.069877 - 22 October 2025

Abstract Background: Alisol A is a natural compound isolated from Alismatis Rhizoma, known for its diverse pharmacological activities, including anticancer and neuroprotective effects. This study aimed to explore the anticancer effects of Alisol A on oral cancer cells and elucidate its underlying mechanisms. Methods: Cell viability was measured by MTT assay, cell cycle by flow cytometry, and apoptosis by Annexin V/PI staining and caspase activation. Regulation of signaling pathways was analyzed using an apoptosis-related protein array, immunoblotting, and specific kinase inhibitors. Results: Alisol A reduced the viability of oral cancer cell lines, induced sub-G1 phase accumulation, and augmented… More >

Zenan Lai, Deming Nie^*

FDMP-Fluid Dynamics & Materials Processing, Vol.21, No.9, pp. 2131-2148, 2025, DOI:10.32604/fdmp.2025.068091 - 30 September 2025

Abstract The lattice Boltzmann method (LBM) is employed to simulate flow around two staggered cylinders within a confined channel. The numerical model is validated against existing experimental data by comparing drag coefficients and Strouhal numbers in the single-cylinder configuration. The study systematically investigates the influence of vertical () and horizontal () spacing between the cylinders, as well as the Reynolds number ( = 0.1–160), on the hydrodynamic forces, streamline patterns, and vortex dynamics. Results indicate that reducing the horizontal spacing  suppresses flow separation behind the upstream cylinder, while either excessively small or large vertical spacing  diminishes separation… More >

Hong Zhang^1,2,#, Ying Zhu^3,#, Xingyu Li^3,#, Zhonghua Liu^1,2, Guoliang Li^1,2, Zhaomiao Lin^1,2, Yongxiang Qiu^1,2, Yongqing Xu^1,2, Shimin Lyu³, Jiyang Wang³, Sixin Qiu^1,2,*

Phyton-International Journal of Experimental Botany, Vol.94, No.8, pp. 2479-2498, 2025, DOI:10.32604/phyton.2025.064850 - 29 August 2025

Abstract Vascular wilt caused by Fusarium oxysporum f. sp. batatas (Fob) is a devastating disease threatening global sweet potato production. To elucidate Fob’s pathogenicity mechanisms and inform effective control strategies, we generated a green fluorescent protein (GFP)-tagged Fob strain to track infection dynamics in sweet potato susceptible cultivar Xinzhonghua and resistant cultivar Xiangshu75-55, respectively. Through cytological observation, we found in the susceptible Xinzhonghua, Fob predominantly colonized stem villi, injured root growth points, and directly invaded vascular bundles through stem wounds. Spore germination peaked at 2–3 h post-inoculation (hpi), followed by cyclical mycelial expansion and sporulation within vascular tissues… More >

Lingjuan Linghu^1,#, Hongying Zhou^2,#, Gang Zheng¹, Tao Yi^1,*

Oncology Research, Vol.33, No.9, pp. 2421-2434, 2025, DOI:10.32604/or.2025.063724 - 28 August 2025

Abstract Objectives: Ovarian cancer, a leading cause of gynecological malignancy-related mortality, is characterized by limited therapeutic options and a poor prognosis. Although pyrimethamine has emerged as a promising candidate demonstrating efficacy in treating various tumors, the precise mechanisms of its antitumor effects remain obscure. This study was specifically designed to investigate the mode of action underlying the antitumor effects of pyrimethamine in preclinical settings. Methods: The effects of pyrimethamine on cellular proliferation were meticulously assessed using both the cell counting kit 8 (CCK-8) assay and the colony formation assay, with the effects further confirmed in a… More >

Kyle Stein^1,*, Andrew A. Mahyari^1,2, Guillermo Francia III³, Eman El-Sheikh³

CMC-Computers, Materials & Continua, Vol.85, No.1, pp. 1001-1018, 2025, DOI:10.32604/cmc.2025.068201 - 29 August 2025

Abstract Deep neural networks (DNNs) and generative AI (GenAI) are increasingly vulnerable to backdoor attacks, where adversaries embed triggers into inputs to cause models to misclassify or misinterpret target labels. Beyond traditional single-trigger scenarios, attackers may inject multiple triggers across various object classes, forming unseen backdoor-object configurations that evade standard detection pipelines. In this paper, we introduce DBOM (Disentangled Backdoor-Object Modeling), a proactive framework that leverages structured disentanglement to identify and neutralize both seen and unseen backdoor threats at the dataset level. Specifically, DBOM factorizes input image representations by modeling triggers and objects as independent primitives in the… More >

Jiazheng Du¹, Ju Chen^1,2, Hongling Ye^1,*, Bing Lin¹, Zhichao Guo¹

CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.1, pp. 791-809, 2025, DOI:10.32604/cmes.2025.066676 - 31 July 2025

Abstract The traditional topology optimization method of continuum structure generally uses quadrilateral elements as the basic mesh. This approach often leads to jagged boundary issues, which are traditionally addressed through post-processing, potentially altering the mechanical properties of the optimized structure. A topology optimization method of Movable Morphable Smooth Boundary (MMSB) is proposed based on the idea of mesh adaptation to solve the problem of jagged boundaries and the influence of post-processing. Based on the ICM method, the rational fraction function is introduced as the filtering function, and a topology optimization model with the minimum weight as More > Graphic Abstract

Huiping Chen^1,*, Xianliang Zheng², Anguo Fu¹

Journal of Psychology in Africa, Vol.35, No.3, pp. 403-409, 2025, DOI:10.32604/jpa.2025.066392 - 31 July 2025

Abstract We explored the relationship between Internet altruistic behavior (IAB) and subjective well-being (SWB) to estimate the effects and directionality of that predictive relationship between the two. Employing cross-lagged models we examined the interaction between IAB and SWB, among 339 college students (females = 53.10%, mean age = 19.02 years, SD = 1.56 years). The students were tracked twice in a period of 5 months. Results showed that college students’ IAB increased significantly, while their SWB remained relatively stable during the two measurement periods. IAB and SWB had significant simultaneous and sequential correlations. SWB at Time More >