Suzana Vieira Rabêlo1, Fernanda Granja da Silva Oliveira2, Michele Miriam Calixto de Lira3, Livia Macedo Dutra3, Adilson Sartoratto4, Marta Cristina Teixeira Duarte4, Maria Claudia dos Santos Luciano5, Maria Francilene Souza Silva5, Cláudia do Ó Pessoa5, Manoel Odorico de Moraes Filho5, Emmanoel Vilaça Costa6, Jackson Roberto Guedes da Silva Almeida1,3,*
Phyton-International Journal of Experimental Botany, Vol.90, No.3, pp. 921-931, 2021, DOI:10.32604/phyton.2021.013305
- 30 March 2021
Abstract This study aimed to identify the chemical composition of essential oil from fruits (EOAF) and the hexanic crude
extract from aerial parts (At-Hex) of atemoya (Annona cherimola x Annona squamosa), a hybrid belonging to the
Annonaceae family. Cytotoxic and antimicrobial activity was also evaluated. OEAF was obtained by hydrodistillation using a Clevenger apparatus, and their composition was analyzed by gas chromatography-mass spectrometry
(GC-MS) analyses. Cytotoxicity was tested against human tumor cell lines HCT-116 (colon carcinoma), SF-295
(glioblastoma), OVCAR-8 (ovarian carcinoma) and HL60 (leukemia) using 3-(4,5-dimethyl-2-thiazolyl)-2,5-
diphenyl-2H-tetrazolium bromide (MTT) assay, while antimicrobial activity was conducted by bioauthography
method More >