Si-Woo Kim, Yong Soo Kim^*

CMC-Computers, Materials & Continua, Vol.86, No.3, 2026, DOI:10.32604/cmc.2025.073492 - 12 January 2026

Abstract Predictive maintenance (PdM) is vital for ensuring the reliability, safety, and cost efficiency of heavy-duty vehicle fleets. However, real-world sensor data are often highly imbalanced, noisy, and temporally irregular, posing significant challenges to model robustness and deployment. Using multivariate time-series data from Scania trucks, this study proposes a novel PdM framework that integrates efficient feature summarization with cost-sensitive hierarchical classification. First, the proposed last_k_summary method transforms recent operational records into compact statistical and trend-based descriptors while preserving missingness, allowing LightGBM to leverage its inherent split rules without ad-hoc imputation. Then, a two-stage LightGBM framework is developed… More >

Muhammad Saad Farooqui¹, Aizaz Ahmad Khattak², Bakri Hossain Awaji³, Nazik Alturki⁴, Noha Alnazzawi⁵, Muhammad Hanif^6,*, Muhammad Shahbaz Khan²

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.3, pp. 4395-4439, 2025, DOI:10.32604/cmes.2025.072023 - 23 December 2025

Abstract Quality of Service (QoS) assurance in programmable IoT and 5G networks is increasingly threatened by cyberattacks such as Distributed Denial of Service (DDoS), spoofing, and botnet intrusions. This paper presents AutoSHARC, a feedback-driven, explainable intrusion detection framework that integrates Boruta and LightGBM–SHAP feature selection with a lightweight CNN–Attention–GRU classifier. AutoSHARC employs a two-stage feature selection pipeline to identify the most informative features from high-dimensional IoT traffic and reduces 46 features to 30 highly informative ones, followed by post-hoc SHAP-guided retraining to refine feature importance, forming a feedback loop where only the most impactful attributes are More >

Hongrong Wang^1,2, Xinjian Li^3,4, Xingjing She¹, Wenjian Ma^1,*

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 2039-2055, 2025, DOI:10.32604/cmes.2025.072572 - 26 November 2025

Abstract In modern complex systems, real-time regression prediction plays a vital role in performance evaluation and risk warning. Nevertheless, existing methods still face challenges in maintaining stability and predictive accuracy under complex conditions. To address these limitations, this study proposes an online prediction approach that integrates event tracking sensitivity analysis with machine learning. Specifically, a real-time event tracking sensitivity analysis method is employed to capture and quantify the impact of key events on system outputs. On this basis, a mutual-information–based self-extraction mechanism is introduced to construct prior weights, which are then incorporated into a LightGBM prediction More >

Adeel Munawar¹, Muhammad Nadeem Ali², Awais Qasim³, Byung-Seo Kim^2,*

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.1, pp. 1189-1211, 2025, DOI:10.32604/cmes.2025.071876 - 30 October 2025

Abstract Cyber-physical systems (CPS) represent a sophisticated integration of computational and physical components that power critical applications such as smart manufacturing, healthcare, and autonomous infrastructure. However, their extensive reliance on internet connectivity makes them increasingly susceptible to cyber threats, potentially leading to operational failures and data breaches. Furthermore, CPS faces significant threats related to unauthorized access, improper management, and tampering of the content it generates. In this paper, we propose an intrusion detection system (IDS) optimized for CPS environments using a hybrid approach by combining a nature-inspired feature selection scheme, such as Grey Wolf Optimization (GWO),… More >

Hui Qi¹, Jingyi Lian², Congjun Rao^2,*

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.1, pp. 995-1028, 2025, DOI:10.32604/cmes.2025.069722 - 30 October 2025

Abstract For the past few years, the prevalence of cardiovascular disease has been showing a year-on-year increase, with a death rate of 2/5. Coronary heart disease (CHD) rates have increased 41% since 1990, which is the number one disease endangering human health in the world today. The risk indicators of CHD are complicated, so selecting effective methods to screen the risk characteristics can make the risk prediction more efficient. In this paper, we present a comprehensive analysis of CHD risk indicators from both data and algorithmic levels, propose a method for CHD risk indicator identification based… More >

Asrar Mahboob¹, Muhammad Rashad¹, Ghulam Abbas¹, Zohaib Mushtaq², Tehseen Mazhar^3,*, Ateeq Ur Rehman^4,*

CMC-Computers, Materials & Continua, Vol.85, No.2, pp. 3805-3823, 2025, DOI:10.32604/cmc.2025.067615 - 23 September 2025

Abstract This paper presents a novel blockchain-embedded cybersecurity framework for industrial solar power systems, integrating immutable machine learning (ML) with distributed ledger technology. Our contribution focused on three factors, Quantum-resistant feature engineering using the UNSW-NB15 dataset adapted for solar infrastructure anomalies. An enhanced Light Gradient Boosting Machine (LightGBM) classifier with blockchain-validated decision thresholds, and A cryptographic proof-of-threat (PoT) consensus mechanism for cyber attack verification. The proposed Immutable LightGBM model with majority voting and cryptographic feature encoding achieves 96.9% detection accuracy with 0.97 weighted average of precision, recall and F1-score, outperforming conventional intrusion detection systems (IDSs) by… More >

Pooja Bidwai^1,2, Shilpa Gite^1,3, Biswajeet Pradhan^4,*, Abdullah Almari⁵

CMC-Computers, Materials & Continua, Vol.84, No.2, pp. 2645-2676, 2025, DOI:10.32604/cmc.2025.061018 - 03 July 2025

Abstract Diabetic Retinopathy (DR) is a critical disorder that affects the retina due to the constant rise in diabetics and remains the major cause of blindness across the world. Early detection and timely treatment are essential to mitigate the effects of DR, such as retinal damage and vision impairment. Several conventional approaches have been proposed to detect DR early and accurately, but they are limited by data imbalance, interpretability, overfitting, convergence time, and other issues. To address these drawbacks and improve DR detection accurately, a distributed Explainable Convolutional Neural network-enabled Light Gradient Boosting Machine (DE-ExLNN) is… More >

Shuqin Zhang¹, Zihao Wang^1,*, Xinyu Su²

CMC-Computers, Materials & Continua, Vol.83, No.3, pp. 5781-5809, 2025, DOI:10.32604/cmc.2025.062080 - 19 May 2025

Abstract The methods of network attacks have become increasingly sophisticated, rendering traditional cybersecurity defense mechanisms insufficient to address novel and complex threats effectively. In recent years, artificial intelligence has achieved significant progress in the field of network security. However, many challenges and issues remain, particularly regarding the interpretability of deep learning and ensemble learning algorithms. To address the challenge of enhancing the interpretability of network attack prediction models, this paper proposes a method that combines Light Gradient Boosting Machine (LGBM) and SHapley Additive exPlanations (SHAP). LGBM is employed to model anomalous fluctuations in various network indicators,… More >

MING YANG^1,#, LIANGZHAO CHU^1,#, SHUKAI LIN², HAN PENG¹, NIYA LONG¹, KAYA XU¹, HUA YANG¹, FENG HAN^1,*, JIAN LIU^1,*

Oncology Research, Vol.33, No.5, pp. 1189-1198, 2025, DOI:10.32604/or.2024.055102 - 18 April 2025

Abstract Background: Glioblastoma (GBM) is one of the most malignant types of central nervous system tumors. Oxygen deprivation in the tumor microenvironment is thought to be an important factor in promoting GBM progression. However, the mechanisms of hypoxia-promoted tumor progression remain elusive. Methods: Alternative splicing of diacylglycerol kinase gamma (DGKG)-Δ exon13 was amplified and verified by PCR-Sanger sequencing. The functions of DGKG and DGKG-Δ exon13 were analyzed by Cell counting kit-8 (CCK-8), Transwell, Matrigel-transwell experiments, and in vivo orthotropic GBM animal models. Transcriptome analyses were done to find out the regulated genes. Results: In this study, we found… More > Graphic Abstract

TANVI VIJAY GUJARAN^1,#, VIGNESH BALAJI EASWARAN^1,#, RUNALI SANKHE¹, PUGAZHANDHI BAKTHAVATCHALAM^2,3, HERMAN SUNIL DSOUZA⁴, K. SREEDHARA RANGANATH PAI^1,*

Oncology Research, Vol.33, No.2, pp. 381-395, 2025, DOI:10.32604/or.2024.049538 - 16 January 2025

Abstract Background: To date, there is no effective cure for the highly malignant brain tumor glioblastoma (GBM). GBM is the most common, aggressive central nervous system tumor (CNS). It commonly originates in glial cells such as microglia, oligodendroglia, astrocytes, or subpopulations of cancer stem cells (CSCs). Glucose plays an important role in the, which energy metabolism of normal and cancer cells, but cancer cells exhibit an increased demand for glucose is required for their differentiation and proliferation. The main aim of this study is to explore the anti-cancer efficacy of the ketogenic diet against GBM. Also,… More >