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    ARTICLE

    miR-143 Inhibits Cell Proliferation of Gastric Cancer Cells Through Targeting GATA6

    Mao Guoping*, Liu Ran, Qin Yanru*

    Oncology Research, Vol.26, No.7, pp. 1023-1029, 2018, DOI:10.3727/096504018X15151515028670

    Abstract Recent studies have suggested that the dysregulation of microRNAs (miRNAs) plays a critical role in the progression of human cancers, including gastric cancer (GC). miR-143 had been reported to function as a tumor suppressor in GC. However, the exact molecular mechanism of how miR-143 participates in GC progression remains to be determined. In this present study, we revealed that the expression of miR-143 was significantly downregulated in human GC tissues and cell lines compared with normal tissues and a normal gastric epithelium cell line. In addition, upregulation of the expression of miR-143 in a GC More >

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