Mao Guoping*, Liu Ran†, Qin Yanru*
Oncology Research, Vol.26, No.7, pp. 1023-1029, 2018, DOI:10.3727/096504018X15151515028670
Abstract Recent studies have suggested that the dysregulation of microRNAs (miRNAs) plays a critical role in the progression of human cancers, including gastric cancer (GC). miR-143 had been reported to function as a tumor
suppressor in GC. However, the exact molecular mechanism of how miR-143 participates in GC progression
remains to be determined. In this present study, we revealed that the expression of miR-143 was significantly
downregulated in human GC tissues and cell lines compared with normal tissues and a normal gastric epithelium cell line. In addition, upregulation of the expression of miR-143 in a GC More >