Ahmed Abdel-Wahab¹, Mohammad Alkhatib^2,*

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-34, 2026, DOI:10.32604/cmc.2025.070010 - 09 December 2025

Abstract Deepfake is a sort of fake media made by advanced AI methods like Generative Adversarial Networks (GANs). Deepfake technology has many useful uses in education and entertainment, but it also raises a lot of ethical, social, and security issues, such as identity theft, the dissemination of false information, and privacy violations. This study seeks to provide a comprehensive analysis of several methods for identifying and circumventing Deepfakes, with a particular focus on image-based Deepfakes. There are three main types of detection methods: classical, machine learning (ML) and deep learning (DL)-based, and hybrid methods. There are… More >

Dawa Chyophel Lepcha^1,*, Bhawna Goyal^2,3, Ayush Dogra⁴, Ahmed Alkhayyat⁵, Prabhat Kumar Sahu⁶, Aaliya Ali⁷, Vinay Kukreja⁴

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 1487-1573, 2025, DOI:10.32604/cmes.2025.070964 - 26 November 2025

Abstract Medical image analysis has become a cornerstone of modern healthcare, driven by the exponential growth of data from imaging modalities such as MRI, CT, PET, ultrasound, and X-ray. Traditional machine learning methods have made early contributions; however, recent advancements in deep learning (DL) have revolutionized the field, offering state-of-the-art performance in image classification, segmentation, detection, fusion, registration, and enhancement. This comprehensive review presents an in-depth analysis of deep learning methodologies applied across medical image analysis tasks, highlighting both foundational models and recent innovations. The article begins by introducing conventional techniques and their limitations, setting the… More >

Sidra Jubair¹, Jie Yang^1,2,*, Bilal Ali³, Walid Emam⁴, Yusra Tashkandy⁴

CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.1, pp. 511-534, 2025, DOI:10.32604/cmes.2025.066514 - 31 July 2025

Abstract Effectively handling imbalanced datasets remains a fundamental challenge in computational modeling and machine learning, particularly when class overlap significantly deteriorates classification performance. Traditional oversampling methods often generate synthetic samples without considering density variations, leading to redundant or misleading instances that exacerbate class overlap in high-density regions. To address these limitations, we propose Wasserstein Generative Adversarial Network Variational Density Estimation WGAN-VDE, a computationally efficient density-aware adversarial resampling framework that enhances minority class representation while strategically reducing class overlap. The originality of WGAN-VDE lies in its density-aware sample refinement, ensuring that synthetic samples are positioned in underrepresented More >

María Belén Rocco, Clara Requena D’Alessio, Valeria Giselle Sánchez, Horacio Eduardo Romeo, María Laura Barreiro Arcos^*

BIOCELL, Vol.49, No.4, pp. 629-646, 2025, DOI:10.32604/biocell.2025.062525 - 30 April 2025

Abstract Introduction: Hyperthyroidism is known to affect various physiological systems, including the immune system. Thyroid hormones (THs) play a crucial role in regulating immune function, and alterations in THs levels can lead to immune dysregulation. Objective: Currently, we aimed to elucidate the effects of hyperthyroidism on immune function in BALB/c mice, with a focus on anatomical and histological changes in lymphoid organs, the immune response to mitogenic stimulation, mitochondrial dynamics, and reactive oxygen species (ROS) production. Methods: Hyperthyroidism was induced in BALB/c mice by administering thyroxine (T4; 14 mg/L) in their drinking water for 30 days. Thyroid… More >

Nizar Zaghden¹, Emad Ibrahim², Mukaram Safaldin^2,*, Mahmoud Mejdoub³

CMC-Computers, Materials & Continua, Vol.83, No.1, pp. 1117-1147, 2025, DOI:10.32604/cmc.2025.061948 - 26 March 2025

Abstract The increasing elderly population has heightened the need for accurate and reliable fall detection systems, as falls can lead to severe health complications. Existing systems often suffer from high false positive and false negative rates due to insufficient training data and suboptimal detection techniques. This study introduces an advanced fall detection model integrating YOLOv8, Faster R-CNN, and Generative Adversarial Networks (GANs) to enhance accuracy and robustness. A modified YOLOv8 architecture serves as the core, utilizing spatial attention mechanisms to improve critical image regions’ detection. Faster R-CNN is employed for fine-grained human posture analysis, while GANs… More >

Tawfeeq Shawly¹, Ahmed A. Alsheikhy^2,*, Yahia Said³, Shaaban M. Shaaban³, Husam Lahza⁴, Aws I. AbuEid⁵, Abdulrahman Alzahrani⁶

CMES-Computer Modeling in Engineering & Sciences, Vol.142, No.3, pp. 3181-3212, 2025, DOI:10.32604/cmes.2025.061608 - 03 March 2025

Abstract Email communication plays a crucial role in both personal and professional contexts; however, it is frequently compromised by the ongoing challenge of spam, which detracts from productivity and introduces considerable security risks. Current spam detection techniques often struggle to keep pace with the evolving tactics employed by spammers, resulting in user dissatisfaction and potential data breaches. To address this issue, we introduce the Divide and Conquer-Generative Adversarial Network Squeeze and Excitation-Based Framework (DaC-GANSAEBF), an innovative deep-learning model designed to identify spam emails. This framework incorporates cutting-edge technologies, such as Generative Adversarial Networks (GAN), Squeeze and… More >

Qi Gu^1,2,3,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.32, No.1, pp. 1-1, 2024, DOI:10.32604/icces.2024.012648

Abstract In the complex field of organ fabrication, which combines developmental biology, bioinspired engineering, and regenerative medicine, the main goal is to closely mimic the detailed structure and function of natural organs. While advanced techniques like 3D bioprinting have made significant strides but often fall short in accurately emulating the dynamic, self-organizing processes fundamental to organogenesis, particularly the nuanced patterns of cellular motility and spatial organization [1]. This issue highlights a big challenge in tissue engineering: making synthetic organs that truly match their natural models. Our work aims to bring together principles of developmental biology with… More >

Laviza Falak Naz¹, Rohail Qamar^2,*, Raheela Asif¹, Muhammad Imran², Saad Ahmed³

Intelligent Automation & Soft Computing, Vol.39, No.5, pp. 855-887, 2024, DOI:10.32604/iasc.2024.055074 - 31 October 2024

Abstract Domain shift is when the data used in training does not match the ones it will be applied to later on under similar conditions. Domain shift will reduce accuracy in results. To prevent this, domain adaptation is done, which adapts the pre-trained model to the target domain. In real scenarios, the availability of labels for target data is rare thus resulting in unsupervised domain adaptation. Herein, we propose an innovative approach where source-free domain adaptation models and Generative Adversarial Networks (GANs) are integrated to improve the performance of computer vision or robotic vision-based systems in… More >

Ain Raal¹, Valeriia Kokitko², Vira Odyntsova², Anne Orav³, Oleh Koshovyi^1,4,*

Phyton-International Journal of Experimental Botany, Vol.93, No.7, pp. 1365-1382, 2024, DOI:10.32604/phyton.2024.053754 - 30 July 2024

Abstract Valeriana officinalis L. is a plant from the Caprifoliaceae family, which is widely distributed in various parts of the world, especially in Europe and Asia. All species of Valeriana are distinguished by their ability to synthesize essential oil, which has a powerful effect on the physiological and mental aspects of the human body. The aim was to study the qualitative and quantitative composition of essential oil from valerian roots, collected in different countries, using the gas chromatography method, and to establish marker compounds for valerian species. 13 samples of commercial roots with rhizomes of V. officinalis from nine… More >

Jingyi Mao, Yuchen Zhou, Yifan Wang, Junyu Li, Ziqing Liu, Fanliang Bu^*

CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 837-855, 2024, DOI:10.32604/cmc.2024.048703 - 25 April 2024

Abstract Voice portrait technology has explored and established the relationship between speakers’ voices and their facial features, aiming to generate corresponding facial characteristics by providing the voice of an unknown speaker. Due to its powerful advantages in image generation, Generative Adversarial Networks (GANs) have now been widely applied across various fields. The existing Voice2Face methods for voice portraits are primarily based on GANs trained on voice-face paired datasets. However, voice portrait models solely constructed on GANs face limitations in image generation quality and struggle to maintain facial similarity. Additionally, the training process is relatively unstable, thereby… More >