Jiateng Zhong*†, Haijun Wang*, Jian Yu‡, Jinghang Zhang‡, Hui Wang†§
Oncology Research, Vol.25, No.6, pp. 959-965, 2017, DOI:10.3727/096504016X14803482769179
Abstract Forkhead box L1 (FOXL1) is a member of the Forkhead box (FOX) superfamily and was reported to be dysregulated in various types of cancers. However, its expression pattern and underlying cellular function in breast
cancer remain largely unexplored. Thus, the aim of this study was to detect FOXL1 expression in breast cancer
and to analyze its role in the progression of breast cancer. Our results demonstrated that FOXL1 expression at
both the mRNA and protein levels was downregulated in breast cancer tissues and cell lines. Ectopic FOXL1
suppressed breast cancer cell proliferation, migration, and invasion More >
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