Fang Chen*1, Wei Xiong*†1, Ke Dou‡, Qing Ran*
Oncology Research, Vol.25, No.8, pp. 1261-1267, 2017, DOI:10.3727/096504017X14871164924588
Abstract Forkhead box K1 (FOXK1) is a member of the FOX transcription factor family and plays an important role in
the development of several tumors. However, the role of FOXK1 in the progression of prostate cancer remains
unknown. Thus, the objectives of this study were to detect the expression of FOXK1 in prostate cancer and to
examine its role in prostate cancer cells. We found that the expression of FOXK1 at both the mRNA and protein
levels was significantly upregulated in human prostate cancer cell lines. In addition, the downregulation of
FOXK1 obviously inhibited the cell… More >
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