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    PROCEEDINGS

    Theoretical Studies on Mechanical Behavior of Vesicles with Confined Filaments

    Xin Yi1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.3, pp. 1-1, 2024, DOI:10.32604/icces.2024.012558

    Abstract The intricate packing of elastic filaments, including cytoskeletal microtubules, actin filaments, and artificial nanotubes, is fundamental to understanding a plethora of cellular functions and their applications in cellular engineering. Through rigorous theoretical analysis, we investigate the packing dynamics of filaments within vesicles and explore the axial stretching of the vesicle–filament system. Our examination reveals how the interplay of stiffness and size ratios between filaments and vesicles drives transitions in vesicle configurations, prompting filament bending or coiling. We construct morphological phase diagrams to elucidate these transitional phenomena, highlighting the influence of pressurized vesicles in enhancing resistance More >

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