Haisong Yang*, Tengxiang Chen†, Shu Xu‡, Shiyong Zhang*, Mengmeng Zhang*
Oncology Research, Vol.27, No.2, pp. 219-226, 2019, DOI:10.3727/096504018X15213126075068
Abstract Breast cancer (BC) is the most common malignant tumor in women. Recently, long noncoding RNAs (lncRNAs)
have been proposed as critical regulators in biological processes, including tumorigenesis. FOXC2-AS1, a single antisense oligonucleotide RNA transcribed from the negative strand of forkhead box protein C2 (FOXC2),
has been identified as an oncogene in osteosarcoma. In the present study, we investigated the prognosis value
and biological role of FOXC2-AS1 in BC. Our findings revealed that FOXC2-AS1 was significantly increased
in BC tissues and cell lines, and Kaplan–Meier survival analysis indicated that a high level of FOXC2-AS1
was associated with poor prognosis of BC… More >
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