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  • Open Access

    ARTICLE

    A Comprehensive Image Processing Framework for Early Diagnosis of Diabetic Retinopathy

    Kusum Yadav1, Yasser Alharbi1, Eissa Jaber Alreshidi1, Abdulrahman Alreshidi1, Anuj Kumar Jain2, Anurag Jain3, Kamal Kumar4, Sachin Sharma5, Brij B. Gupta6,7,8,*

    CMC-Computers, Materials & Continua, Vol.81, No.2, pp. 2665-2683, 2024, DOI:10.32604/cmc.2024.053565 - 18 November 2024

    Abstract In today’s world, image processing techniques play a crucial role in the prognosis and diagnosis of various diseases due to the development of several precise and accurate methods for medical images. Automated analysis of medical images is essential for doctors, as manual investigation often leads to inter-observer variability. This research aims to enhance healthcare by enabling the early detection of diabetic retinopathy through an efficient image processing framework. The proposed hybridized method combines Modified Inertia Weight Particle Swarm Optimization (MIWPSO) and Fuzzy C-Means clustering (FCM) algorithms. Traditional FCM does not incorporate spatial neighborhood features, making More >

  • Open Access

    ARTICLE

    Identification of M2 macrophage-related genes for establishing a prognostic model in pancreatic cancer: FCGR3A as key gene

    ZHEN WANG1, JUN FU1, SAISAI ZHU1, HAODONG TANG2, KUI SHI1, JIHUA YANG3, MENG WANG3, MENGGE WU1, DUNFENG QI1,*

    Oncology Research, Vol.32, No.12, pp. 1851-1866, 2024, DOI:10.32604/or.2024.055286 - 13 November 2024

    Abstract Background: Pancreatic ductal adenocarcinoma (PDAC) has a rich and complex tumor immune microenvironment (TIME). M2 macrophages are among the most extensively infiltrated immune cells in the TIME and are necessary for the growth and migration of cancers. However, the mechanisms and targets mediating M2 macrophage infiltration in pancreatic cancer remain elusive. Methods: The M2 macrophage infiltration score of patients was assessed using the xCell algorithm. Using weighted gene co-expression network analysis (WGCNA), module genes associated with M2 macrophages were identified, and a predictive model was designed. The variations in immunological cell patterns, cancer mutations, and… More > Graphic Abstract

    Identification of M2 macrophage-related genes for establishing a prognostic model in pancreatic cancer: <i>FCGR3A</i> as key gene

  • Open Access

    PROCEEDINGS

    A Novel Damage Model for Face-Centered Cubic Crystal Materials Incorporating Microscopic Crystal Cleavage and Slip Failure Mechanisms

    Qianyu Xia1, Zhixin Zhan1,*, Weiping Hu1, Qingchun Meng1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.29, No.1, pp. 1-1, 2024, DOI:10.32604/icces.2024.011238

    Abstract The occurrence of crystal cleavage and slip at the microscopic level in single crystal materials serves as the fundamental underlying factors leading to their macroscopic failures. Therefore, investigating the failure mechanisms and damage processes at the scale of slip systems significantly enhances our comprehension of the degradation and failure patterns exhibited by crystal materials.
    In this study, based on the theory of crystal plasticity, we examine the effects of microscopic damage on the slip systems concerning the failure of face-centered cubic (FCC) crystal materials. Additionally, we develop a novel damage model for FCC crystal materials, incorporating… More >

  • Open Access

    ARTICLE

    A Double-Interactively Recurrent Fuzzy Cerebellar Model Articulation Controller Model Combined with an Improved Particle Swarm Optimization Method for Fall Detection

    Jyun-Guo Wang*

    Computer Systems Science and Engineering, Vol.48, No.5, pp. 1149-1170, 2024, DOI:10.32604/csse.2024.052931 - 13 September 2024

    Abstract In many Eastern and Western countries, falling birth rates have led to the gradual aging of society. Older adults are often left alone at home or live in a long-term care center, which results in them being susceptible to unsafe events (such as falls) that can have disastrous consequences. However, automatically detecting falls from video data is challenging, and automatic fall detection methods usually require large volumes of training data, which can be difficult to acquire. To address this problem, video kinematic data can be used as training data, thereby avoiding the requirement of creating… More >

  • Open Access

    ARTICLE

    Knowledge-Driven Possibilistic Clustering with Automatic Cluster Elimination

    Xianghui Hu1, Yiming Tang2,3, Witold Pedrycz3,4, Jiuchuan Jiang5,*, Yichuan Jiang1,*

    CMC-Computers, Materials & Continua, Vol.80, No.3, pp. 4917-4945, 2024, DOI:10.32604/cmc.2024.054775 - 12 September 2024

    Abstract Traditional Fuzzy C-Means (FCM) and Possibilistic C-Means (PCM) clustering algorithms are data-driven, and their objective function minimization process is based on the available numeric data. Recently, knowledge hints have been introduced to form knowledge-driven clustering algorithms, which reveal a data structure that considers not only the relationships between data but also the compatibility with knowledge hints. However, these algorithms cannot produce the optimal number of clusters by the clustering algorithm itself; they require the assistance of evaluation indices. Moreover, knowledge hints are usually used as part of the data structure (directly replacing some clustering centers),… More >

  • Open Access

    ARTICLE

    Fuzzy C-Means Algorithm Based on Density Canopy and Manifold Learning

    Jili Chen1,2, Hailan Wang2, Xiaolan Xie1,2,*

    Computer Systems Science and Engineering, Vol.48, No.3, pp. 645-663, 2024, DOI:10.32604/csse.2023.037957 - 20 May 2024

    Abstract Fuzzy C-Means (FCM) is an effective and widely used clustering algorithm, but there are still some problems. considering the number of clusters must be determined manually, the local optimal solutions is easily influenced by the random selection of initial cluster centers, and the performance of Euclid distance in complex high-dimensional data is poor. To solve the above problems, the improved FCM clustering algorithm based on density Canopy and Manifold learning (DM-FCM) is proposed. First, a density Canopy algorithm based on improved local density is proposed to automatically deter-mine the number of clusters and initial cluster… More >

  • Open Access

    ARTICLE

    SDH-FCOS: An Efficient Neural Network for Defect Detection in Urban Underground Pipelines

    Bin Zhou, Bo Li*, Wenfei Lan, Congwen Tian, Wei Yao

    CMC-Computers, Materials & Continua, Vol.78, No.1, pp. 633-652, 2024, DOI:10.32604/cmc.2023.046667 - 30 January 2024

    Abstract Urban underground pipelines are an important infrastructure in cities, and timely investigation of problems in underground pipelines can help ensure the normal operation of cities. Owing to the growing demand for defect detection in urban underground pipelines, this study developed an improved defect detection method for urban underground pipelines based on fully convolutional one-stage object detector (FCOS), called spatial pyramid pooling-fast (SPPF) feature fusion and dual detection heads based on FCOS (SDH-FCOS) model. This study improved the feature fusion component of the model network based on FCOS, introduced an SPPF network structure behind the last… More >

  • Open Access

    ARTICLE

    Influences of Co-Flow and Counter-Flow Modes of Reactant Flow Arrangement on a PEMFC at Start-Up

    Qianqian Shao1, Min Wang2,*, Nuo Xu1

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.2, pp. 1337-1356, 2024, DOI:10.32604/cmes.2023.044313 - 29 January 2024

    Abstract To investigate the influences of co-flow and counter-flow modes of reactant flow arrangement on a proton exchange membrane fuel cell (PEMFC) during start-up, unsteady physical and mathematical models fully coupling the flow, heat, and electrochemical reactions in a PEMFC are established. The continuity equation and momentum equation are solved by handling pressure-velocity coupling using the SIMPLE algorithm. The electrochemical reaction rates in the catalyst layers (CLs) of the cathode and anode are calculated using the Butler-Volmer equation. The multiphase mixture model describes the multiphase transport process of gas mixtures and liquid water in the fuel… More >

  • Open Access

    ARTICLE

    Research on ECMS Based on Segmented Path Braking Energy Recovery in a Fuel Cell Vehicle

    Wen Sun1, Meijing Li2, Guoxiang Li1, Ke Sun1,*, Shuzhan Bai1,*

    Energy Engineering, Vol.121, No.1, pp. 95-110, 2024, DOI:10.32604/ee.2023.042096 - 27 December 2023

    Abstract Proton exchange membrane fuel cells are widely regarded as having the potential to replace internal combustion engines in vehicles. Since fuel cells cannot recover energy and have a slow dynamic response, they need to be used with different power sources. Developing efficient energy management strategies to achieve excellent fuel economy is the goal of research. This paper proposes an adaptive equivalent fuel minimum consumption strategy (AECMS) to solve the problem of the poor economy of the whole vehicle caused by the wrong selection of equivalent factors (EF) in traditional ECMS. In this method, the kinematics More >

  • Open Access

    ARTICLE

    Mathematical Modelling and Simulations of Active Direct Methanol Fuel Cell

    RABIRANJAN MURMUa,b, DEBASHIS ROYa, HAREKRUSHNA SUTARb

    Journal of Polymer Materials, Vol.40, No.3-4, pp. 125-139, 2023, DOI:10.32381/JPM.2023.40.3-4.1

    Abstract A one dimensional isothermal model is proposed by modelling the kinetics of methanol transport at anode flow channel (AFC), membrane and cathode catalyst layer of direct methanol fuel cell (DMFC). Analytical model is proposed to predict methanol cross-over rate through the electrolyte membrane and cell performance. The model presented in this paper considered methanol diffusion and electrochemical oxidation at the anode and cathode channels. The analytical solution of the proposed model was simulated in a MATLAB environment to obtain the polarization curve and leakage current. The effect of methanol concentration on cell voltage and leakage More >

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