JULING FENG^1,3, HAODONG CHEN¹, YANGBO LIU¹, QIDI AI¹, YANTAO YANG¹, LEI ZHAO⁴, SHIFENG CHU^2,#,*, NAIHONG CHEN^1,2,#,*

BIOCELL, Vol.48, No.6, pp. 981-990, 2024, DOI:10.32604/biocell.2024.050011

Abstract Introduction: Chemokine-like factor 1 (CKLF1) is a chemokine that is overexpressed in several diseases. Our previous findings revealed a significant increase in CKLF1 expression in the ischemic brain, suggesting its potential as a therapeutic target for ischemic stroke. Methods: In this study, we examined the expression dynamics of CKLF1 in both in vivo and in vitro models of ischemic cardiac injury. Myocardial infarction (MI) was induced in vivo by ligation of the left anterior descending artery (LAD) of the rat heart. The levels of CKLF1, Creatine Kinase MB Isoenzyme (CK-MB), and Lactate dehydrogenase (LDH) in the serum were… More > Graphic Abstract

Kristamtini¹, Sugeng Widodo², Heni Purwaningsih³, Arlyna Budi Pustika¹, Setyorini Widyayanti¹, Arif Muazam¹, Arini Putri Hanifa^1,*, Joko Triastono², Dewi Sahara², Heni Sulistyawati Purwaning Rahayu², Pandu Laksono², Diah Arina Fahmi², Sutardi¹, Joko Pramono⁴, Rachmiwati Yusuf¹

Phyton-International Journal of Experimental Botany, Vol.93, No.5, pp. 1007-1021, 2024, DOI:10.32604/phyton.2024.048770

Abstract Sorghum (Sorghum bicolor L. Moench) is an essential food crop for more than 750 million people in tropical and sub-tropical dry climates of Africa, India, and Latin America. The domestic sorghum market in Indonesia is still limited to the eastern region (East Nusa Tenggara, West Nusa Tenggara, Java, and South Sulawesi). Therefore, it is crucial to carry out sorghum research on drylands. This research aimed to investigate the effect of sorghum genotype and planting distance and their interaction toward growth and sorghum’s productivity in the Gunungkidul dryland, Yogyakarta, Indonesia. In addition, the farm business analysis, including… More >

Yuping Bian^*, Xiu Wan, Xiaoyu Zhou

Energy Engineering, Vol.121, No.6, pp. 1637-1656, 2024, DOI:10.32604/ee.2024.047678

Abstract To address uncertainty as well as transient stability constraints simultaneously in the preventive control of wind farm systems, a novel three-stage optimization strategy is established in this paper. In the first stage, the probabilistic multi-objective particle swarm optimization based on the point estimate method is employed to cope with the stochastic factors. The transient security region of the system is accurately ensured by the interior point method in the second stage. Finally, the verification of the final optimal objectives and satisfied constraints are enforced in the last stage. Furthermore, the proposed strategy is a general More >

Emmanuel Oluwatobi Asani^1,2,3, Aderemi Elisha Okeyinka⁴, Sunday Adeola Ajagbe^5,6, Ayodele Ariyo Adebiyi¹, Roseline Oluwaseun Ogundokun^1,2,7,*, Temitope Samson Adekunle⁸, Pragasen Mudali⁵, Matthew Olusegun Adigun⁵

CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 1581-1597, 2024, DOI:10.32604/cmc.2024.047898

Abstract The study presents the Half Max Insertion Heuristic (HMIH) as a novel approach to solving the Travelling Salesman Problem (TSP). The goal is to outperform existing techniques such as the Farthest Insertion Heuristic (FIH) and Nearest Neighbour Heuristic (NNH). The paper discusses the limitations of current construction tour heuristics, focusing particularly on the significant margin of error in FIH. It then proposes HMIH as an alternative that minimizes the increase in tour distance and includes more nodes. HMIH improves tour quality by starting with an initial tour consisting of a ‘minimum’ polygon and iteratively adding… More >

YARA ALZGHOUL, HALA J. BANI ISSA, AHMAD K. SANAJLEH, TAQWA ALABDUH, FATIMAH RABABAH, MAHA AL-SHDAIFAT, EJLAL ABU-EL-RUB^*, FATIMAH ALMAHASNEH, RAMADA R. KHASAWNEH, AYMAN ALZU’BI, HUTHAIFA MAGABLEH

BIOCELL, Vol.48, No.4, pp. 559-569, 2024, DOI:10.32604/biocell.2024.048056

Abstract Mesenchymal stem cells (MSCs) are ideal candidates for treating many cardiovascular diseases. MSCs can modify the internal cardiac microenvironment to facilitate their immunomodulatory and differentiation abilities, which are essential to restore heart function. MSCs can be easily isolated from different sources, including bone marrow, adipose tissues, umbilical cord, and dental pulp. MSCs from various sources differ in their regenerative and therapeutic abilities for cardiovascular disorders. In this review, we will summarize the therapeutic potential of each MSC source for heart diseases and highlight the possible molecular mechanisms of each source to restore cardiac function. More >

Yingchao Li^1,*, Jianbin Wang¹, Haibin Wang²

Energy Engineering, Vol.121, No.4, pp. 1049-1065, 2024, DOI:10.32604/ee.2023.045228

Abstract With the increasing demand for electrical services, wind farm layout optimization has been one of the biggest challenges that we have to deal with. Despite the promising performance of the heuristic algorithm on the route network design problem, the expressive capability and search performance of the algorithm on multi-objective problems remain unexplored. In this paper, the wind farm layout optimization problem is defined. Then, a multi-objective algorithm based on Graph Neural Network (GNN) and Variable Neighborhood Search (VNS) algorithm is proposed. GNN provides the basis representations for the following search algorithm so that the expressiveness… More >

Maria Inês Clara^1,2,3,*, Maria Cristina Canavarro^2,3, Ana Severina⁴, Susana Ramos⁴, Carla Rafael⁴, Ana Allen Gomes^1,2,3

Psycho-Oncologie, Vol.18, No.1, pp. 49-57, 2024, DOI:10.32604/po.2023.044320

Abstract Objectif: L’objectif de l’étude fut de comparer la fatigue ressentie par les patients du cancer par rapport à celle de la population en générale, ainsi que d’examiner les facteurs de risque psychobiologiques associés à la fatigue. Matériel et méthodes: Dans cette étude quantitative et transversale, nous avons analysé les indicateurs cliniques et sociodémographiques de 389 participants (68.38% de femmes) : 148 patients du cancer sous traitement actif, 55 patients dans l’après-traitement d’un cancer, 75 patients atteints d’une autre maladie chronique et 111 personnes en bonne santé. Résultats: La fatigue s’exprimait de manière différente chez les patients ayant… More >

Longle Cheng^1,2, Xiru Li¹, Shiyu Fang², Wansu Pan¹, He Zhao^1,*, Haibo Tan¹, Xiaofeng Li^1,2

CMC-Computers, Materials & Continua, Vol.78, No.2, pp. 2491-2509, 2024, DOI:10.32604/cmc.2024.047166

Abstract Peer-to-peer (P2P) overlay networks provide message transmission capabilities for blockchain systems. Improving data transmission efficiency in P2P networks can greatly enhance the performance of blockchain systems. However, traditional blockchain P2P networks face a common challenge where there is often a mismatch between the upper-layer traffic requirements and the underlying physical network topology. This mismatch results in redundant data transmission and inefficient routing, severely constraining the scalability of blockchain systems. To address these pressing issues, we propose FPSblo, an efficient transmission method for blockchain networks. Our inspiration for FPSblo stems from the Farthest Point Sampling (FPS)… More >

ANWAR ALI^1,#, SREEKANTH REDDY OBIREDDY^2,#, WING-FU LAI^3,*

BIOCELL, Vol.48, No.2, pp. 163-171, 2024, DOI:10.32604/biocell.2023.043839

Abstract Farnesol is a C15 isoprenyl alcohol generated from the hydrolysis of farnesyl diphosphate under the action of farnesol synthase in plants. Although this sesquiterpenoid alcohol has been exploited in a wide variety of industrial applications, serious discussions on the possible use of this agent in disease treatment have been scant until now. In this article, we review the current understanding of the physiological properties of farnesol and the potential use of the agent as a candidate for treatment development. In fact, since the turn of the last century, farnesol has been found not only to More >

Chen Gu^1,*, Caiyu Wang¹, Mengjiao Du², Kan Yi², Bihong Zhu¹, Hao Wang², Shu Dai¹

The International Conference on Computational & Experimental Engineering and Sciences, Vol.27, No.3, pp. 1-1, 2023, DOI:10.32604/icces.2023.09776

Abstract Site measurement is essential to the meteorological and oceanographic parameters of offshore wind farms. A floating lidar measurement buoy was deployed at a Qingzhou VI wind farm where is 45-80 km away from Guangdong coast. The field observation including wind and wave data start from March, 2021.The lidar wind data is compared and calibrated with the fixed wind tower data for three months, the accuracy meets the standard of stadge3 carbon trust. In this study, all these data are used to recalibrate for the met-ocean model to relies extreme conditions, such as Typhoon Kompasu(2118) and More >