Oncology Research Editorial Office

Oncology Research, Vol.34, No.2, 2026, DOI:10.32604/or.2025.078460 - 19 January 2026

Abstract This article has no abstract. More >

Hoang-Dieu Vu^1,2, Duc-Nghia Tran³, Quang-Tu Pham¹, Ngoc-Linh Nguyen^4,*, Duc-Tan Tran^1,*

CMC-Computers, Materials & Continua, Vol.85, No.2, pp. 2819-2835, 2025, DOI:10.32604/cmc.2025.068355 - 23 September 2025

Abstract This study presents CGB-Net, a novel deep learning architecture specifically developed for classifying twelve distinct sleep positions using a single abdominal accelerometer, with direct applicability to gastroesophageal reflux disease (GERD) monitoring. Unlike conventional approaches limited to four basic postures, CGB-Net enables fine-grained classification of twelve clinically relevant sleep positions, providing enhanced resolution for personalized health assessment. The architecture introduces a unique integration of three complementary components: 1D Convolutional Neural Networks (1D-CNN) for efficient local spatial feature extraction, Gated Recurrent Units (GRU) to capture short-term temporal dependencies with reduced computational complexity, and Bidirectional Long Short-Term Memory… More >

Fei Ren^1,#, Yansen Cai^2,#, Yang Song^1,*

Oncology Research, Vol.33, No.8, pp. 2055-2074, 2025, DOI:10.32604/or.2025.061301 - 18 July 2025

Abstract Objectives: Epigenetic changes, particularly N6-methyladenosine (m6A) modifications, play a pivotal role in cancer development. This study explored the role of ovarian tumor deubiquitinase 7B (OTUD7B) in esophageal squamous cell carcinoma (ESCC) in the context of m6A methylation and the hypoxia-inducible factor-1α (HIF-1α) pathway. Methods: The GSE179267 dataset was used to conduct differential gene expression analysis to identify key m6A-enriched genes. The Cancer Genome Atlas (TCGA), Cancer Cell Line Encyclopedia (CCLE), and Sequence-based RNA Adenosine Methylation Site Predictor (SRAMP) databases were used to evaluate the expression of OTUD7B in ESCC and its correlation with methyltransferase-like 14… More >

Oncology Research Editorial Office

Oncology Research, Vol.33, No.6, pp. 1509-1509, 2025, DOI:10.32604/or.2024.062048 - 29 May 2025

Abstract This article has no abstract. More >

NURAN BEDOLLA^#, HAO WU^#, LINYU LIU, XUETING LIU, YANLI REN^*

Oncology Research, Vol.33, No.6, pp. 1473-1484, 2025, DOI:10.32604/or.2025.060151 - 29 May 2025

Abstract Background: Gallic acid (GA), a plant-derived polyphenol, possesses diverse biological functions such as reducing inflammation and against tumors. Currently, the influence of GA on the resistance of esophageal squamous cell carcinoma (ESCC) cells to cisplatin (DDP) is not well understood. Methods: Cell counting kit-8 assay examined how GA affected KYSE30 and TE-1 cell viability. 5-Ethynyl-2′-deoxyuridine and TdT-mediated dUTP Nick-End labeling staining detected cell proliferation and apoptosis. Clone formation assay, flow cytometry, Carboxyfluorescein diacetate succinimidyl ester fluorescent probes, and Transwell assay determined cell biological properties, and 2′,7′-Dichlorofluorescin diacetate (DCFH-DA) fluorescent probes detected oxidative stress levels. Signal… More > Graphic Abstract

Oncology Research Editorial Office

Oncology Research, Vol.33, No.5, pp. 1253-1253, 2025, DOI:10.32604/or.2024.056916 - 18 April 2025

Abstract This article has no abstract. More >

Oncology Research Editorial Office

Oncology Research, Vol.32, No.11, pp. 1823-1823, 2024, DOI:10.32604/or.2024.056896 - 16 October 2024

Abstract This article has no abstract. More >

JINGJING TIAN^1,*, XIBAO HU², XINRONG ZHANG¹

Oncology Research, Vol.32, No.5, pp. 925-931, 2024, DOI:10.32604/or.2023.042447 - 23 April 2024

Abstract To confirm the relationship between Circ_0003855 and EC, we purchased the Human esophageal carcinoma cell line Eca109 and normal human esophageal epithelial cells HEEC, and the expression levels of Circ_0003855, miR-622, and FLOT1 were detected. The results show that Circ_0003855 and FLOT1 were highly expressed in Eca109 cells, while miR-622 was lowly expressed (p < 0.05). Subsequently, Circ_0003855 small interfering RNA (si-Circ_0003855) and its negative control (si-NC) were used to detect changes in cellular biological behaviors. We found that the activity of Eca109 cells was reduced after interfering with the expression of Circ_0003855, and miR-622 expression More >

DAIXIN ZHAO¹, QINGYU WANG², JIANBO WANG^1,*

BIOCELL, Vol.48, No.2, pp. 271-281, 2024, DOI:10.32604/biocell.2023.029094 - 23 February 2024

Abstract Background: Esophageal cancer (ESCA) is a common digestive tract tumor. As a result, optimization of the early diagnosis of ESCA and identifying the contributing prognostic genes is urgently required. Herein, the prognosis of mitochondrial autophagy-related genes was analyzed in different subtypes of ESCA, and prognostic models were constructed to identify the immune cell infiltration with significant differences between subtypes. Methods: The Cancer Genome Atlas database was searched to download 185 ESCA samples, covering gene expression level data and clinical follow-up data, and 179 samples from the Gene Expression Omnibus database for subsequent validation analysis. The… More >

Guilin Wu^1,2, Shenghua Huang¹, Tingting Liu³, Zhuoni Yang³, Yuesong Wu², Guihong Wei¹, Peng Yu^1,*, Qilin Zhang⁴, Jun Feng⁴, Bo Zeng^5,*

CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.3, pp. 2709-2725, 2024, DOI:10.32604/cmes.2023.031399 - 15 December 2023

Abstract Esophageal disease is a common disorder of the digestive system that can severely affect the quality of life and prognosis of patients. Esophageal stenting is an effective treatment that has been widely used in clinical practice. However, esophageal stents of different types and parameters have varying adaptability and effectiveness for patients, and they need to be individually selected according to the patient’s specific situation. The purpose of this study was to provide a reference for clinical doctors to choose suitable esophageal stents. We used 3D printing technology to fabricate esophageal stents with different ratios of… More >