Yimin Liu^1,#, Bin Liu^2,3,4,#, Huabin Gao¹, Jinlong Wang⁵, Jingya Duan¹, Xiaolan Huang¹, Yuexi Liu¹, Ying Huang¹, Wenjing Liao¹, Ruonan Li^1,*, Hua Linghu^1,*

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.069007 - 30 December 2025

Abstract Objectives: High-grade serous ovarian cancer (HGSOC), the most common subtype of epithelial ovarian cancer (EOC), exhibits a mesenchymal phenotype characterized by fibrotic stroma and poor prognosis. Human epididymis protein 4 (HE4), a key diagnostic biomarker for ovarian cancer, is involved in fibrotic processes in several non-malignant diseases. Given the clinical significance of stromal fibrosis in HGSOC and the potential link between HE4 and fibrosis, this study aimed to investigate the role of HE4 in the formation of stromal fibrosis in HGSOC. Methods: A total of 126 patients with gynecological conditions were included and divided into… More > Graphic Abstract

Hui Yi^1,2,#, Hongjian Shi^2,3,#, Fuquan Kan^2,4,#, Fan Han², Lei Wan⁵, Xiaoyang Hong¹, Zhe Zhao¹, Junjie Shao², Gang Wang¹, Hui Wang¹, Hua Yan⁵, Xiujuan Shi¹, Ran Zhang^2,6,*, Gengxu Zhou^1,*

Congenital Heart Disease, Vol.20, No.4, pp. 519-530, 2025, DOI:10.32604/chd.2025.067164 - 18 September 2025

Abstract Background: To investigate the impact of preoperative extracorporeal membrane oxygenation (ECMO) on clinical outcomes in pediatric heart transplantation (PHT). Methods: This retrospective cohort analysis was conducted on 19 pediatric heart transplant recipients, divided into two groups: ECMO and non-ECMO, based on whether preoperative ECMO was utilized. We evaluated the patients’ surgical conditions, postoperative complications, and survival rates. Additionally, the analysis focused on the differences and correlations in clinical characteristics, inflammatory markers, and long-term survival outcomes. Results: There was no statistically significant difference in perioperative survival rates between the ECMO group (85.7%) and the non-ECMO group (83.3%). However,… More >

Yaqi Zhang^1,#, Liang Hu^1,#, Yuxi Zhang¹, Bo Qian¹, Jirong Qi^1,2, Wei Peng^1,2,*

Congenital Heart Disease, Vol.20, No.1, pp. 55-60, 2025, DOI:10.32604/chd.2025.063072 - 18 March 2025

Abstract Background: Carotid artery pseudoaneurysm in children is rare; typically caused by trauma; surgical interventions and infection. These aneurysms can lead to significant neurological and vascular risks; and their management remains challenging. While endovascular therapy has become the standard for giant pseudoaneurysms in adults; its use in children is limited. No established guidelines or long-term safety data exist for pediatric endovascular treatment. We present a child who developed a carotid artery pseudoaneurysm after venoarterial extracorporeal membrane oxygenation (VA-ECMO) support and heart transplantation; highlighting the management strategies and outcomes. Case Description: A 4-year-old boy with dilated cardiomyopathy was admitted… More >

Jianxin Feng^*, Jianhao Zhang, Ge Cao, Zhiguo Liu, Yuanming Ding

CMC-Computers, Materials & Continua, Vol.82, No.1, pp. 1049-1068, 2025, DOI:10.32604/cmc.2024.058374 - 03 January 2025

Abstract Multivariate time series forecasting is widely used in traffic planning, weather forecasting, and energy consumption. Series decomposition algorithms can help models better understand the underlying patterns of the original series to improve the forecasting accuracy of multivariate time series. However, the decomposition kernel of previous decomposition-based models is fixed, and these models have not considered the differences in frequency fluctuations between components. These problems make it difficult to analyze the intricate temporal variations of real-world time series. In this paper, we propose a series decomposition-based Mamba model, DecMamba, to obtain the intricate temporal dependencies and… More >

Wen Sun¹, Meijing Li², Guoxiang Li¹, Ke Sun^1,*, Shuzhan Bai^1,*

Energy Engineering, Vol.121, No.1, pp. 95-110, 2024, DOI:10.32604/ee.2023.042096 - 27 December 2023

Abstract Proton exchange membrane fuel cells are widely regarded as having the potential to replace internal combustion engines in vehicles. Since fuel cells cannot recover energy and have a slow dynamic response, they need to be used with different power sources. Developing efficient energy management strategies to achieve excellent fuel economy is the goal of research. This paper proposes an adaptive equivalent fuel minimum consumption strategy (AECMS) to solve the problem of the poor economy of the whole vehicle caused by the wrong selection of equivalent factors (EF) in traditional ECMS. In this method, the kinematics More >

Qiqi Li¹, Longfei Ma¹, Zheng Jiang¹, Mingyong Li^1,*, Bo Jin²

CMC-Computers, Materials & Continua, Vol.75, No.2, pp. 3713-3728, 2023, DOI:10.32604/cmc.2023.037463 - 31 March 2023

Abstract In recent years, cross-modal hash retrieval has become a popular research field because of its advantages of high efficiency and low storage. Cross-modal retrieval technology can be applied to search engines, cross-modal medical processing, etc. The existing main method is to use a multi-label matching paradigm to finish the retrieval tasks. However, such methods do not use fine-grained information in the multi-modal data, which may lead to sub-optimal results. To avoid cross-modal matching turning into label matching, this paper proposes an end-to-end fine-grained cross-modal hash retrieval method, which can focus more on the fine-grained semantic… More >

AAYUSHI RANDHAWA^1,2, SAYAN DEB DUTTA¹, KEYA GANGULY¹, TEJAL V. PATIL^1,2, RACHMI LUTHFIKASARI¹, KI-TAEK LIM^1,2,*

BIOCELL, Vol.47, No.4, pp. 789-808, 2023, DOI:10.32604/biocell.2023.026217 - 08 March 2023

Abstract Tissues are made up of cells and the extracellular matrix (ECM) which surrounds them. These cells and tissues are actively adaptable to enduring significant stress that occurs in daily life. This astonishing mechanical stress develops due to the interaction between the live cells and the non-living ECM. Cells in the matrix microenvironment can sense the signals and forces produced and initiate a signaling cascade that plays a crucial role in the body’s normal functioning and influences various properties of the native cells, including growth, proliferation, and differentiation. However, the matrix’s characteristic features also impact the More >

Wen Sun, Hao Liu, Ming Han, Ke Sun, Shuzhan Bai^*, Guoxiang Li^*

FDMP-Fluid Dynamics & Materials Processing, Vol.18, No.4, pp. 867-882, 2022, DOI:10.32604/fdmp.2022.018923 - 06 April 2022

Abstract Fuel cell hybrid electric vehicles are currently being considered as ideal means to solve the energy crisis and global warming in today’s society. In this context, this paper proposes a method to solve the problem related to the dependence of the so-called optimal equivalent factor (determined in the framework of the equivalent consumption minimum strategy-ECMS) on the working conditions. The simulation results show that under typical conditions (some representative cities being considered), the proposed strategy can maintain the power balance; for different initial battery’s states of charge (SOC), after the SOC stabilizes, the fuel consumption More >

OK-HYEON KIM^1,2,#, EUN RAN KIM^3,#, JUN HYUNG PARK², HYUN JUNG LEE^1,2,*

BIOCELL, Vol.46, No.6, pp. 1439-1443, 2022, DOI:10.32604/biocell.2022.018921 - 07 February 2022

Abstract Exogenously delivered mesenchymal stromal cells (MSCs) are therapeutically beneficial owing to their paracrine effect; they secrete various cytokines, nucleic acids, and proteins. Multiple bioengineering techniques can help MSC cultures to release secretomes by providing stem cell niche-like conditions (both structurally and functionally). Various scaffolds mimic the natural extracellular matrix (ECM) using both natural and synthetic polymers, providing favorable environments for MSC proliferation and differentiation. Depending on material properties, either topographically or elastically structured scaffolds can be fabricated. Three-dimensional scaffolds have tunable substrate rigidities and structures, aiding MSC cultivation. Decellularized ECM-derived hydrogels are similar to the More >

RAFIQ AHMED BHAT¹, SYED MANZOOR ALI², YOOSUF ALI ASHRAF MUHAMMAD HUSSENBOCUS³, AKANKSHA RATHI⁴, JAVAID AKHTER BHAT⁵, ABDUL ALEEM KHAN⁶, SYED MAQBOOL², RAJA SAQIB IQBAL⁷, MD MONOWARUL ISLAM⁸, YONGSHENG QU⁹, YOU ZHANG⁹, YUXIAO SUN¹, WENTAO XIAO⁹, ABHISHEK TIBREWAL¹⁰, CHUANYU GAO^1,*

BIOCELL, Vol.46, No.5, pp. 1139-1150, 2022, DOI:10.32604/biocell.2022.016833 - 06 January 2022

Abstract The adverse outcomes of a ventricular heart failure (left, right or biventricular) caused by cardiogenic shock are aggravated by lung oedema and organ mal perfusion. Despite advances in medical sciences, revascularisation and mechanical hemodynamic support have proved ineffective in reducing the mortality rate in such patients. A thorough study of the data available about cardio-vascular diseases reveals that the application of conventional methods of treatment are least helpful to practically restore normal functions of heart when it experiences end-stage systolic ventricular failure. Thus, to overcome the challenges and find alternatives to address this issue, percutaneous… More >