Wen Sun¹, Meijing Li², Guoxiang Li¹, Ke Sun^1,*, Shuzhan Bai^1,*

Energy Engineering, Vol.121, No.1, pp. 95-110, 2024, DOI:10.32604/ee.2023.042096 - 27 December 2023

Abstract Proton exchange membrane fuel cells are widely regarded as having the potential to replace internal combustion engines in vehicles. Since fuel cells cannot recover energy and have a slow dynamic response, they need to be used with different power sources. Developing efficient energy management strategies to achieve excellent fuel economy is the goal of research. This paper proposes an adaptive equivalent fuel minimum consumption strategy (AECMS) to solve the problem of the poor economy of the whole vehicle caused by the wrong selection of equivalent factors (EF) in traditional ECMS. In this method, the kinematics More >

Qiqi Li¹, Longfei Ma¹, Zheng Jiang¹, Mingyong Li^1,*, Bo Jin²

CMC-Computers, Materials & Continua, Vol.75, No.2, pp. 3713-3728, 2023, DOI:10.32604/cmc.2023.037463 - 31 March 2023

Abstract In recent years, cross-modal hash retrieval has become a popular research field because of its advantages of high efficiency and low storage. Cross-modal retrieval technology can be applied to search engines, cross-modal medical processing, etc. The existing main method is to use a multi-label matching paradigm to finish the retrieval tasks. However, such methods do not use fine-grained information in the multi-modal data, which may lead to sub-optimal results. To avoid cross-modal matching turning into label matching, this paper proposes an end-to-end fine-grained cross-modal hash retrieval method, which can focus more on the fine-grained semantic… More >

AAYUSHI RANDHAWA^1,2, SAYAN DEB DUTTA¹, KEYA GANGULY¹, TEJAL V. PATIL^1,2, RACHMI LUTHFIKASARI¹, KI-TAEK LIM^1,2,*

BIOCELL, Vol.47, No.4, pp. 789-808, 2023, DOI:10.32604/biocell.2023.026217 - 08 March 2023

Abstract Tissues are made up of cells and the extracellular matrix (ECM) which surrounds them. These cells and tissues are actively adaptable to enduring significant stress that occurs in daily life. This astonishing mechanical stress develops due to the interaction between the live cells and the non-living ECM. Cells in the matrix microenvironment can sense the signals and forces produced and initiate a signaling cascade that plays a crucial role in the body’s normal functioning and influences various properties of the native cells, including growth, proliferation, and differentiation. However, the matrix’s characteristic features also impact the More >

Wen Sun, Hao Liu, Ming Han, Ke Sun, Shuzhan Bai^*, Guoxiang Li^*

FDMP-Fluid Dynamics & Materials Processing, Vol.18, No.4, pp. 867-882, 2022, DOI:10.32604/fdmp.2022.018923 - 06 April 2022

Abstract Fuel cell hybrid electric vehicles are currently being considered as ideal means to solve the energy crisis and global warming in today’s society. In this context, this paper proposes a method to solve the problem related to the dependence of the so-called optimal equivalent factor (determined in the framework of the equivalent consumption minimum strategy-ECMS) on the working conditions. The simulation results show that under typical conditions (some representative cities being considered), the proposed strategy can maintain the power balance; for different initial battery’s states of charge (SOC), after the SOC stabilizes, the fuel consumption More >

OK-HYEON KIM^1,2,#, EUN RAN KIM^3,#, JUN HYUNG PARK², HYUN JUNG LEE^1,2,*

BIOCELL, Vol.46, No.6, pp. 1439-1443, 2022, DOI:10.32604/biocell.2022.018921 - 07 February 2022

Abstract Exogenously delivered mesenchymal stromal cells (MSCs) are therapeutically beneficial owing to their paracrine effect; they secrete various cytokines, nucleic acids, and proteins. Multiple bioengineering techniques can help MSC cultures to release secretomes by providing stem cell niche-like conditions (both structurally and functionally). Various scaffolds mimic the natural extracellular matrix (ECM) using both natural and synthetic polymers, providing favorable environments for MSC proliferation and differentiation. Depending on material properties, either topographically or elastically structured scaffolds can be fabricated. Three-dimensional scaffolds have tunable substrate rigidities and structures, aiding MSC cultivation. Decellularized ECM-derived hydrogels are similar to the More >

RAFIQ AHMED BHAT¹, SYED MANZOOR ALI², YOOSUF ALI ASHRAF MUHAMMAD HUSSENBOCUS³, AKANKSHA RATHI⁴, JAVAID AKHTER BHAT⁵, ABDUL ALEEM KHAN⁶, SYED MAQBOOL², RAJA SAQIB IQBAL⁷, MD MONOWARUL ISLAM⁸, YONGSHENG QU⁹, YOU ZHANG⁹, YUXIAO SUN¹, WENTAO XIAO⁹, ABHISHEK TIBREWAL¹⁰, CHUANYU GAO^1,*

BIOCELL, Vol.46, No.5, pp. 1139-1150, 2022, DOI:10.32604/biocell.2022.016833 - 06 January 2022

Abstract The adverse outcomes of a ventricular heart failure (left, right or biventricular) caused by cardiogenic shock are aggravated by lung oedema and organ mal perfusion. Despite advances in medical sciences, revascularisation and mechanical hemodynamic support have proved ineffective in reducing the mortality rate in such patients. A thorough study of the data available about cardio-vascular diseases reveals that the application of conventional methods of treatment are least helpful to practically restore normal functions of heart when it experiences end-stage systolic ventricular failure. Thus, to overcome the challenges and find alternatives to address this issue, percutaneous… More >

PETRA KRAUS^1,*, ANKITA SAMANTA¹, SINA LUFKIN², THOMAS LUFKIN¹

BIOCELL, Vol.46, No.4, pp. 893-898, 2022, DOI:10.32604/biocell.2022.018432 - 15 December 2021

Abstract Pain and lifestyle changes are common consequences of intervertebral disc degeneration (IVDD) and affect a large part of the aging population. The stemness of cells is exploited in the field of regenerative medicine as key to treat degenerative diseases. Transplanted cells however often face delivery and survival challenges, especially in tissues with a naturally harsh microniche environment such as the intervertebral disc. Recent interest in the secretome of stem cells, especially cargo protected from microniche-related decay as frequently present in degenerating tissues, provides new means of rejuvenating ailing cells and tissues. Exosomes, a type of More >

Yan Zu^1,2, Qiang Li¹, Chun Yang^2,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 106-106, 2019, DOI:10.32604/mcb.2019.07132

Abstract Extracellular matrix (ECM) elasticity affects the function of a variety of cells. Integrins are transmembrane receptors that considered to be a sensor of cellular mechanical stimulation. The activity of integrins is strongly influenced by glycans through glycosylation events and the establishment of glycan-mediated interactions. Our study found that the level of β1 integrin N-linked glycosylation was significantly down-regulated on softer ECM. Further, sialic acid is a common monosaccharide modified at the end of the sugar chain during N-glycosylation. We subjected the enriched sialylated glycoproteins to gel-based proteomic identification by tandem mass spectrometry and found that… More >

Runze Zhao¹, Tingting Xia¹, Mengyue Wang¹, Fan Feng¹, Wanqian Liu^1,*, Li Yang^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 77-77, 2019, DOI:10.32604/mcb.2019.07155

Abstract This study was focus on the exploring the therapeutic function of lysyl oxidase (LOX) in rat nucleus pulposus (NP) cells in intervertebral disc degeneration (IVDD). To do this, a Sprague-Dawley (SD) rat caudal spine degeneration model was established by puncturing the Co5-6 disc. NP cells apoptosis and extracellular matrix (ECM) degeneration in IVDD were evaluated by real-time quantitative reverse transcription-polymerase chain reaction (RT-qPCR), Hematoxylin-Eosin (H&E) and immunofluorescence. Then, the therapeutic effect of LOX on IVDD was evaluated by histological staining. In vitro, the regulator effect of LOX on degenerate rat NP cell was explored. ECM… More >

William Leineweber¹, Stephanie I. Fraley^1,2,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 9-9, 2019, DOI:10.32604/mcb.2019.08504

Abstract Cell-extracellular matrix (ECM) interactions are critical modulators of repair and regeneration. However, variability within individual cells of the same cell type and within the ECM microenvironment can lead to heterogeneous outcomes that may limit the reliable application of cell-biomaterial constructs in regenerative medicine. Understanding the origins of heterogeneity is critical to overcoming this challenge and requires measurement of cell-ECM interactions at the single cell level. There are four core biophysical modules that cells employ to interact with their surrounding ECM: protrusion, adhesion, contractility, and matrix remodeling. Conventional approaches measure these interactions in separate experiments on… More >