KANG SUN1, DONGQIN WANG1, ZHIQIANG ZHANG1, YINLONG HUANG3, XIAOFU LIAN3, JIALE HUA3, JING ZHANG3,*, CHAOQUN LIAN1,2,*
BIOCELL, Vol.47, No.2, pp. 297-307, 2023, DOI:10.32604/biocell.2023.023553
Abstract Columbianetin acetate (CE) is one of the effective components of Angelica pubescens. So far, the specific role and molecular mechanism of CE in pancreatic cancer are not clear. Thus, this study aimed to explore the specific mechanism of CE on pancreatic cancer. The target genes combined with CE were predicted through the PharmMapper database and the 3D molecular structure of CE. Then, the Cancer Genome Atlas (TCGA) and Cistrome data browser (DB) databases were used to screen Meiotic nuclear divisions 1 (MND1)-related genes, transcription factors, and transcription factor data sets, and the intersection of the above data sets. The “limma”… More >
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