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  • Open Access

    REVIEW

    Three-dimensional cell-based strategies for liver regeneration

    DAN GUO1, XI XIA2,*, JIAN YANG1,*

    BIOCELL, Vol.48, No.7, pp. 1023-1036, 2024, DOI:10.32604/biocell.2024.051095

    Abstract Liver regeneration and the development of effective therapies for liver failure remain formidable challenges in modern medicine. In recent years, the utilization of 3D cell-based strategies has emerged as a promising approach for addressing these urgent clinical requirements. This review provides a thorough analysis of the application of 3D cell-based approaches to liver regeneration and their potential impact on patients with end-stage liver failure. Here, we discuss various 3D culture models that incorporate hepatocytes and stem cells to restore liver function and ameliorate the consequences of liver failure. Furthermore, we explored the challenges in transitioning More >

  • Open Access

    ARTICLE

    Oscillatory Dynamics of a Spherical Solid in a Liquid in an Axisymmetric Variable Cross Section Channel

    Ivan Karpunin*

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.6, pp. 1219-1232, 2024, DOI:10.32604/fdmp.2024.051062

    Abstract The dynamics of a solid spherical body in an oscillating liquid flow in a vertical axisymmetric channel of variable cross section is experimentally studied. It is shown that the oscillating liquid leads to the generation of intense averaged flows in each of the channel segments. The intensity and direction of these flows depend on the dimensionless oscillating frequency. In the region of studied frequencies, the dynamics of the considered body is examined when the primary vortices emerging in the flow occupy the whole region in each segment. For a fixed frequency, an increase in the… More >

  • Open Access

    ARTICLE

    A Power Data Anomaly Detection Model Based on Deep Learning with Adaptive Feature Fusion

    Xiu Liu, Liang Gu*, Xin Gong, Long An, Xurui Gao, Juying Wu

    CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 4045-4061, 2024, DOI:10.32604/cmc.2024.048442

    Abstract With the popularisation of intelligent power, power devices have different shapes, numbers and specifications. This means that the power data has distributional variability, the model learning process cannot achieve sufficient extraction of data features, which seriously affects the accuracy and performance of anomaly detection. Therefore, this paper proposes a deep learning-based anomaly detection model for power data, which integrates a data alignment enhancement technique based on random sampling and an adaptive feature fusion method leveraging dimension reduction. Aiming at the distribution variability of power data, this paper developed a sliding window-based data adjustment method for… More >

  • Open Access

    ARTICLE

    Hybrid Gene Selection Methods for High-Dimensional Lung Cancer Data Using Improved Arithmetic Optimization Algorithm

    Mutasem K. Alsmadi*

    CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 5175-5200, 2024, DOI:10.32604/cmc.2024.044065

    Abstract Lung cancer is among the most frequent cancers in the world, with over one million deaths per year. Classification is required for lung cancer diagnosis and therapy to be effective, accurate, and reliable. Gene expression microarrays have made it possible to find genetic biomarkers for cancer diagnosis and prediction in a high-throughput manner. Machine Learning (ML) has been widely used to diagnose and classify lung cancer where the performance of ML methods is evaluated to identify the appropriate technique. Identifying and selecting the gene expression patterns can help in lung cancer diagnoses and classification. Normally,… More >

  • Open Access

    ARTICLE

    Generalized nth-Order Perturbation Method Based on Loop Subdivision Surface Boundary Element Method for Three-Dimensional Broadband Structural Acoustic Uncertainty Analysis

    Ruijin Huo1,2,3, Qingxiang Pei1,2,3, Xiaohui Yuan1,*, Yanming Xu3

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.2, pp. 2053-2077, 2024, DOI:10.32604/cmes.2024.049185

    Abstract In this paper, a generalized th-order perturbation method based on the isogeometric boundary element method is proposed for the uncertainty analysis of broadband structural acoustic scattering problems. The Burton-Miller method is employed to solve the problem of non-unique solutions that may be encountered in the external acoustic field, and the th-order discretization formulation of the boundary integral equation is derived. In addition, the computation of loop subdivision surfaces and the subdivision rules are introduced. In order to confirm the effectiveness of the algorithm, the computed results are contrasted and analyzed with the results under Monte More >

  • Open Access

    ARTICLE

    Development of a Three-Dimensional Multiscale Octree SBFEM for Viscoelastic Problems of Heterogeneous Materials

    Xu Xu1, Xiaoteng Wang1, Haitian Yang1, Zhenjun Yang2, Yiqian He1,3,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.2, pp. 1831-1861, 2024, DOI:10.32604/cmes.2024.048199

    Abstract The multiscale method provides an effective approach for the numerical analysis of heterogeneous viscoelastic materials by reducing the degree of freedoms (DOFs). A basic framework of the Multiscale Scaled Boundary Finite Element Method (MsSBFEM) was presented in our previous works, but those works only addressed two-dimensional problems. In order to solve more realistic problems, a three-dimensional MsSBFEM is further developed in this article. In the proposed method, the octree SBFEM is used to deal with the three-dimensional calculation for numerical base functions to bridge small and large scales, the three-dimensional image-based analysis can be conveniently… More >

  • Open Access

    ARTICLE

    Three-Dimensional Printing Conformal Cooling with Structural Lattices for Plastic Injection Molding

    Suping Shen1,2, Baris Burak Kanbur1,2, Chenlong Wu2, Fei Duan1,2,*

    Frontiers in Heat and Mass Transfer, Vol.22, No.2, pp. 397-415, 2024, DOI:10.32604/fhmt.2024.048984

    Abstract The design of three-dimensional printing based conformal cooling channels (CCCs) in injection molding holds great significance. Compared to CCCs, conformal cooling (CC) cavity solutions show promise in delivering enhanced cooling performance for plastic products, although they have been underexplored. In this research, CC cavity is designed within the mold geometry, reinforced by body-centered cubic (BCC) lattice structures to enhance mechanical strength. Three distinct BCC lattice variations have been integrated into the CC cavity: the BCC structure, BCC with cubes, and BCC with pillars. The thermal performances of the BCC lattice-added CC cavity are assessed numerically… More > Graphic Abstract

    Three-Dimensional Printing Conformal Cooling with Structural Lattices for Plastic Injection Molding

  • Open Access

    ARTICLE

    Research on Quantitative Identification of Three-Dimensional Connectivity of Fractured-Vuggy Reservoirs

    Xingliang Deng1, Peng Cao2,*, Yintao Zhang1, Yuhui Zhou3, Xiao Luo1, Liang Wang3

    Energy Engineering, Vol.121, No.5, pp. 1195-1207, 2024, DOI:10.32604/ee.2023.045870

    Abstract The fractured-vuggy carbonate oil resources in the western basin of China are extremely rich. The connectivity of carbonate reservoirs is complex, and there is still a lack of clear understanding of the development and topological structure of the pore space in fractured-vuggy reservoirs. Thus, effective prediction of fractured-vuggy reservoirs is difficult. In view of this, this work employs adaptive point cloud technology to reproduce the shape and capture the characteristics of a fractured-vuggy reservoir. To identify the complex connectivity among pores, fractures, and vugs, a simplified one-dimensional connectivity model is established by using the meshless More >

  • Open Access

    ARTICLE

    HgaNets: Fusion of Visual Data and Skeletal Heatmap for Human Gesture Action Recognition

    Wuyan Liang1, Xiaolong Xu2,*

    CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 1089-1103, 2024, DOI:10.32604/cmc.2024.047861

    Abstract Recognition of human gesture actions is a challenging issue due to the complex patterns in both visual and skeletal features. Existing gesture action recognition (GAR) methods typically analyze visual and skeletal data, failing to meet the demands of various scenarios. Furthermore, multi-modal approaches lack the versatility to efficiently process both uniform and disparate input patterns. Thus, in this paper, an attention-enhanced pseudo-3D residual model is proposed to address the GAR problem, called HgaNets. This model comprises two independent components designed for modeling visual RGB (red, green and blue) images and 3D skeletal heatmaps, respectively. More… More >

  • Open Access

    ARTICLE

    4-dimensional Printing of Multi-material, Multi-shape Changing Shape Memory Polymer Composites

    MANIKANDAN.N1,*, RAJESH.P.K1

    Journal of Polymer Materials, Vol.38, No.3-4, pp. 327-336, 2021, DOI:10.32381/JPM.2021.38.3-4.12

    Abstract In this research, a new method to fabricate multi-material, multi-shape changing polymer composites is proposed. The method aims to reduce the number of thermomechanical programming steps involved in achieving shape change in a shape memory polymer (SMP) composite structure by including the programming steps directly into the printing process. After a single step of mechanical deformation and thermal loading, the SMP fibers can be activated sequentially to control the shape change. Composite strip samples were fabricated using a Stratasys Objet 260 multimaterial printer. Two polymer inks VeroPureWhite and Agilus30 were used as primary materials. The… More >

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