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  • Open Access

    REVIEW

    Immunomodulatory and chemopreventive effects of resveratrol on the digestive system cancers

    MEIR DJALDETTI*

    Oncology Research, Vol.32, No.9, pp. 1389-1399, 2024, DOI:10.32604/or.2024.049745 - 23 August 2024

    Abstract Resveratrol (RSV), the primary polyphenol found in grapes, has been revealed to have anti-inflammatory properties by reducing the capacity of the peripheral blood mononuclear cells to produce pro-inflammatory cytokines, including IL-1β, IL-6, IL-1ra and TNFα. Considering the close association between chronic inflammation and cancer development, RSV’s immunomodulatory properties are one way by which the polyphenol may inhibit cancer initiation, proliferation, neovascularization, and migration. Resveratrol influences the generation of microtumor environment which is one of the key factors in cancer progress. In addition to immunomodulation, RSV inhibits cancer development by expressing anti-oxidant effects, causing cell cycle… More > Graphic Abstract

    Immunomodulatory and chemopreventive effects of resveratrol on the digestive system cancers

  • Open Access

    REVIEW

    Suicide in Digestive System Cancers: A Scoping Review

    Jie Chen1,2, Xiaoping Ding1,2, Xin Peng3, Deying Hu1,3,*

    International Journal of Mental Health Promotion, Vol.25, No.1, pp. 1-20, 2023, DOI:10.32604/ijmhp.2022.022578 - 29 November 2022

    Abstract Digestive system cancers are important causes of morbidity and mortality worldwide. Cancer patients are more likely to commit suicide. The objective of this scoping review is to provide a comprehensive and updated summary of the existing literature on suicide among patients with digestive system cancers to identify the incidence and risk factors relevant to suicide in these populations. The PRISMA-Scr (Preferred Reporting Items for Systematic reviews and Meta-Analyses extension protocol for scoping reviews) protocol was used. The review was based on relevant articles published prior to January 2022 in databases of Web of Science and… More >

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