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    Mesenchymal stem cells and cell-free preparations for treating atopic dermatitis

    TRINIDAD MONTERO-VILCHEZ1,2,*, MANUEL SANCHEZ-DIAZ1,2, CAROLINA MONTERO-VILCHEZ3, ALVARO SIERRA-SANCHEZ2, SALVADOR ARIAS-SANTIAGO1,2,4

    BIOCELL, Vol.46, No.11, pp. 2363-2367, 2022, DOI:10.32604/biocell.2022.021399

    Abstract Atopic dermatitis (AD) is a chronic cutaneous inflammatory disease caused by an interaction between genetic, immune and epidermal barrier factors. Several treatments can be used to treat this disease but there are patients that do not respond to actual drugs. So, there is a need to develop effective therapies for AD. Mesenchymal stem cells (MSCs) are non-hematopoietic multipotent adult progenitor cells with immunomodulatory power and self-regenerating capacity to repair tissue damage, so they could be a potential effective treatment for AD. MSCs-Conditioned Medium (CM) and MSCs-exosomes are cell-free preparation with molecules secreted by stem cells that could be also beneficial… More >

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