MICHELE DI COSOLA1,§; STEFANIA CANTORE2,§,*; MARIO GIOSUÈ BALZANELLI3; CIRO GARGIULO ISACCO2,3; KIEU CAO DIEM NGUYEN2,3; RAJIV SAINI2; ANNARITA MALCANGI4; MARGHERITA TUMEDEI5; MARIATERESA AMBROSINO1; ANTONIO MANCINI2; SALVATORE SCACCO6; RICCARDO NOCINI7; LUIGI SANTACROCE2; ANDREA BALLINI8,9,#,*; EDOARDO BRAUNER10,#
BIOCELL, Vol.46, No.4, pp. 923-929, 2022, DOI:10.32604/biocell.2022.018409
- 15 December 2021
Abstract The human teeth and oral cavity harbor various populations of mesenchymal stem cells (MSCs), so called
dental-derived stem cells (D-dSCs) with self-renewing and multilineage differentiation capabilities. D-dSCs properties
involves a strong paracrine component resulting from the high levels of bioactive molecules they secrete in response
to the local microenvironment. Altogether, this viewpoint develops a general picture of current innovative strategies
to employ D-dSCs combined with biomaterials and bioactive factors for regenerative medicine purposes, and offers
information regarding the available scientific data and possible applications. More >
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