Hira Akhtar Butt¹, Khoula Said Al Harthy², Mumtaz Ali Shah³, Mudassar Hussain^2,*, Rashid Amin^4,*, Mujeeb Ur Rehman¹

CMC-Computers, Materials & Continua, Vol.81, No.2, pp. 3003-3031, 2024, DOI:10.32604/cmc.2024.057185 - 18 November 2024

Abstract Detecting sophisticated cyberattacks, mainly Distributed Denial of Service (DDoS) attacks, with unexpected patterns remains challenging in modern networks. Traditional detection systems often struggle to mitigate such attacks in conventional and software-defined networking (SDN) environments. While Machine Learning (ML) models can distinguish between benign and malicious traffic, their limited feature scope hinders the detection of new zero-day or low-rate DDoS attacks requiring frequent retraining. In this paper, we propose a novel DDoS detection framework that combines Machine Learning (ML) and Ensemble Learning (EL) techniques to improve DDoS attack detection and mitigation in SDN environments. Our model… More >

SULING XU¹, XIAO LI², WENXUE MA^3,*

Oncology Research, Vol.32, No.11, pp. 1701-1708, 2024, DOI:10.32604/or.2024.055161 - 16 October 2024

Abstract The environment surrounding a tumor, known as the tumor microenvironment (TME), plays a role in how cancer progresses and responds to treatment. It poses both challenges and opportunities for improving cancer therapy. Recent progress in understanding the TME complexity and diversity has led to approaches for treating cancer. This perspective discusses the strategies for targeting the TME, such as adjusting networks using extracellular vesicles to deliver drugs and enhancing immune checkpoint inhibitors (ICIS) through combined treatments. Furthermore, it highlights adoptive cell transfer (ACT) therapies as an option for tumors. By studying how components of the More >

Khawaja Tahir Mehmood^1,2,*, Shahid Atiq¹, Intisar Ali Sajjad³, Muhammad Majid Hussain⁴, Malik M. Abdul Basit²

CMES-Computer Modeling in Engineering & Sciences, Vol.141, No.2, pp. 1673-1708, 2024, DOI:10.32604/cmes.2024.053903 - 27 September 2024

Abstract Software-Defined Networking (SDN), with segregated data and control planes, provides faster data routing, stability, and enhanced quality metrics, such as throughput (T_h), maximum available bandwidth (B_d(max)), data transfer (D_Transfer), and reduction in end-to-end delay (D_(E-E)). This paper explores the critical work of deploying SDN in large­scale Data Center Networks (DCNs) to enhance its Quality of Service (QoS) parameters, using logically distributed control configurations. There is a noticeable increase in Delay_(E-E) when adopting SDN with a unified (single) control structure in big DCNs to handle Hypertext Transfer Protocol (HTTP) requests causing a reduction in network quality parameters (B_d(max), T_h, D_Transfer, D_(E-E),… More > Graphic Abstract

Abdijalil Abdullahi^1,2, Selvakumar Manickam^2,*

CMC-Computers, Materials & Continua, Vol.80, No.3, pp. 4361-4385, 2024, DOI:10.32604/cmc.2024.054215 - 12 September 2024

Abstract Internet Exchange Point (IXP) is a system that increases network bandwidth performance. Internet exchange points facilitate interconnection among network providers, including Internet Service Providers (ISPs) and Content Delivery Providers (CDNs). To improve service management, Internet exchange point providers have adopted the Software Defined Network (SDN) paradigm. This implementation is known as a Software-Defined Exchange Point (SDX). It improves network providers’ operations and management. However, performance issues still exist, particularly with multi-hop topologies. These issues include switch memory costs, packet processing latency, and link failure recovery delays. The paper proposes Enhanced Link Failure Rerouting (ELFR), an… More >

Dong-Wook Kim¹, Gun-Yoon Sin², Kwangsoo Kim³, Jaesik Kang³, Sun-Young Im³, Myung-Mook Han^1,*

CMC-Computers, Materials & Continua, Vol.80, No.3, pp. 3637-3653, 2024, DOI:10.32604/cmc.2024.054108 - 12 September 2024

Abstract In the rapidly evolving field of cybersecurity, the challenge of providing realistic exercise scenarios that accurately mimic real-world threats has become increasingly critical. Traditional methods often fall short in capturing the dynamic and complex nature of modern cyber threats. To address this gap, we propose a comprehensive framework designed to create authentic network environments tailored for cybersecurity exercise systems. Our framework leverages advanced simulation techniques to generate scenarios that mirror actual network conditions faced by professionals in the field. The cornerstone of our approach is the use of a conditional tabular generative adversarial network (CTGAN),… More >

Ahmad Rahdari^1,6, Ahmad Jalili², Mehdi Esnaashari³, Mehdi Gheisari^1,4,7,8,*, Alisa A. Vorobeva⁵, Zhaoxi Fang¹, Panjun Sun^1,*, Viktoriia M. Korzhuk⁵, Ilya Popov⁵, Zongda Wu¹, Hamid Tahaei¹

CMC-Computers, Materials & Continua, Vol.80, No.2, pp. 2511-2533, 2024, DOI:10.32604/cmc.2024.052994 - 15 August 2024

Abstract Software-Defined Networking (SDN) represents a significant paradigm shift in network architecture, separating network logic from the underlying forwarding devices to enhance flexibility and centralize deployment. Concurrently, the Internet of Things (IoT) connects numerous devices to the Internet, enabling autonomous interactions with minimal human intervention. However, implementing and managing an SDN-IoT system is inherently complex, particularly for those with limited resources, as the dynamic and distributed nature of IoT infrastructures creates security and privacy challenges during SDN integration. The findings of this study underscore the primary security and privacy challenges across application, control, and data planes.… More >

Feiyu Yan^1,2, Xin Chen¹, Zhenzhen Wang¹, Yuxuan Xia¹, Dehui Zheng¹, Sirui Xue¹, Hongliang Zhao^1,2, Zhiwei Huang^1,2, Yuan Niu^1,2, Guoliang Zhang^1,2,*

Phyton-International Journal of Experimental Botany, Vol.93, No.7, pp. 1421-1440, 2024, DOI:10.32604/phyton.2024.053914 - 30 July 2024

Abstract Melatonin and abscisic acid, as major plant hormones, play important roles in the physiological and biochemical activities of crops, but the interaction between the two under salt stress is not yet clear. This study investigated the endogenous levels of melatonin and abscisic acid in rice by using exogenous melatonin, abscisic acid, and their synthetic inhibitors, and examined their interactions under salt stress. The research results indicate that melatonin and abscisic acid can improve rice salt tolerance. Melatonin alleviated the salt sensitivity caused by abscisic acid deficiency, increased antioxidant enzyme activity and antioxidant content in rice More >

Risalina Myrtha^1,2,*, Hasanah Mumpuni^3,4, Real Kusumanjaya Marsam^3,4, Dyah Wulan Anggrahini^3,4, Anggoro Budi Hartopo^3,4, Lucia Kris Dinarti^3,4

Congenital Heart Disease, Vol.19, No.3, pp. 315-324, 2024, DOI:10.32604/chd.2024.051587 - 26 July 2024

Abstract Background and Objective: The most feared complication of uncorrected secundum Atrial Septal Defect (ASD) is pulmonary arterial hypertension (PAH). Pulmonary vascular resistance (PVR) is crucial in detecting precapillary pulmonary hypertension (PH) to guide the need for PAH-specific therapy. There is a change in the cut-off value of PVR according to the recently updated PH guideline. How echocardiographic PVR (PVR) correlates to PVR by right heart catheterization (RHC) (PVR) according to the new guidelines has not been known. The aim of this study is to determine the reliability of PVR in detecting PAH in Uncorrected Ostium… More > Graphic Abstract

Johari Abdul Rahim¹, Rosdiadee Nordin^2,*, Oluwatosin Ahmed Amodu^3,4

CMC-Computers, Materials & Continua, Vol.80, No.1, pp. 747-800, 2024, DOI:10.32604/cmc.2024.047009 - 18 July 2024

Abstract Software Defined Networking (SDN) is programmable by separation of forwarding control through the centralization of the controller. The controller plays the role of the ‘brain’ that dictates the intelligent part of SDN technology. Various versions of SDN controllers exist as a response to the diverse demands and functions expected of them. There are several SDN controllers available in the open market besides a large number of commercial controllers; some are developed to meet carrier-grade service levels and one of the recent trends in open-source SDN controllers is the Open Network Operating System (ONOS). This paper… More >

Jiarui Zhang¹, Dan Liu^2,*, Kan Cao², Ping Xiong², Xiaotong Ji³, Yanze Xu¹, Yunfei Mu¹

Energy Engineering, Vol.121, No.8, pp. 2065-2083, 2024, DOI:10.32604/ee.2024.050342 - 19 July 2024

Abstract The system performance of grid-connected photovoltaic (PV) has a serious impact on the grid stability. To improve the control performance and shorten the convergence time, a predefined-time controller based on backstepping technology and dynamic surface control is formulated for the inverter in the grid-connected photovoltaic. The time-varying tuning functions are introduced into state-tracking errors to realize the predefined-time control effect. To address the “computational explosion problem” in the design process of backstepping control, dynamic surface control is adopted to avoid the analytical calculations of virtual control. The disturbances of the PV system are estimated and More >