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  • Open Access

    ARTICLE

    CHDTEPDB: Transcriptome Expression Profile Database and Interactive Analysis Platform for Congenital Heart Disease

    Ziguang Song1,2, Jiangbo Yu1, Mengmeng Wang3, Weitao Shen4, Chengcheng Wang1, Tianyi Lu1, Gaojun Shan1, Guo Dong1, Yiru Wang1, Jiyi Zhao1,*

    Congenital Heart Disease, Vol.18, No.6, pp. 693-701, 2023, DOI:10.32604/chd.2024.048081

    Abstract CHDTEPDB (URL: ) is a manually integrated database for congenital heart disease (CHD) that stores the expression profiling data of CHD derived from published papers, aiming to provide rich resources for investigating a deeper correlation between human CHD and aberrant transcriptome expression. The development of human diseases involves important regulatory roles of RNAs, and expression profiling data can reflect the underlying etiology of inherited diseases. Hence, collecting and compiling expression profiling data is of critical significance for a comprehensive understanding of the mechanisms and functions that underpin genetic diseases. CHDTEPDB stores the expression profiles of over 200 sets of 7… More >

  • Open Access

    ARTICLE

    A New Method for Diagnosis of Leukemia Utilizing a Hybrid DL-ML Approach for Binary and Multi-Class Classification on a Limited-Sized Database

    Nilkanth Mukund Deshpande1,2, Shilpa Gite3,4,*, Biswajeet Pradhan5,6, Abdullah Alamri7, Chang-Wook Lee8,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.1, pp. 593-631, 2024, DOI:10.32604/cmes.2023.030704

    Abstract Infection of leukemia in humans causes many complications in its later stages. It impairs bone marrow’s ability to produce blood. Morphological diagnosis of human blood cells is a well-known and well-proven technique for diagnosis in this case. The binary classification is employed to distinguish between normal and leukemia-infected cells. In addition, various subtypes of leukemia require different treatments. These sub-classes must also be detected to obtain an accurate diagnosis of the type of leukemia. This entails using multi-class classification to determine the leukemia subtype. This is usually done using a microscopic examination of these blood cells. Due to the requirement… More > Graphic Abstract

    A New Method for Diagnosis of Leukemia Utilizing a Hybrid DL-ML Approach for Binary and Multi-Class Classification on a Limited-Sized Database

  • Open Access

    ARTICLE

    Fusion of Hash-Based Hard and Soft Biometrics for Enhancing Face Image Database Search and Retrieval

    Ameerah Abdullah Alshahrani*, Emad Sami Jaha, Nahed Alowidi

    CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 3489-3509, 2023, DOI:10.32604/cmc.2023.044490

    Abstract The utilization of digital picture search and retrieval has grown substantially in numerous fields for different purposes during the last decade, owing to the continuing advances in image processing and computer vision approaches. In multiple real-life applications, for example, social media, content-based face picture retrieval is a well-invested technique for large-scale databases, where there is a significant necessity for reliable retrieval capabilities enabling quick search in a vast number of pictures. Humans widely employ faces for recognizing and identifying people. Thus, face recognition through formal or personal pictures is increasingly used in various real-life applications, such as helping crime investigators… More >

  • Open Access

    ARTICLE

    Utilizing Machine Learning with Unique Pentaplet Data Structure to Enhance Data Integrity

    Abdulwahab Alazeb*

    CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 2995-3014, 2023, DOI:10.32604/cmc.2023.043173

    Abstract Data protection in databases is critical for any organization, as unauthorized access or manipulation can have severe negative consequences. Intrusion detection systems are essential for keeping databases secure. Advancements in technology will lead to significant changes in the medical field, improving healthcare services through real-time information sharing. However, reliability and consistency still need to be solved. Safeguards against cyber-attacks are necessary due to the risk of unauthorized access to sensitive information and potential data corruption. Disruptions to data items can propagate throughout the database, making it crucial to reverse fraudulent transactions without delay, especially in the healthcare industry, where real-time… More >

  • Open Access

    ARTICLE

    Fuzzy Logic Inference System for Managing Intensive Care Unit Resources Based on Knowledge Graph

    Ahmad F Subahi*, Areej Athama

    CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 3801-3816, 2023, DOI:10.32604/cmc.2023.034522

    Abstract With the rapid growth in the availability of digital health-related data, there is a great demand for the utilization of intelligent information systems within the healthcare sector. These systems can manage and manipulate this massive amount of health-related data and encourage different decision-making tasks. They can also provide various sustainable health services such as medical error reduction, diagnosis acceleration, and clinical services quality improvement. The intensive care unit (ICU) is one of the most important hospital units. However, there are limited rooms and resources in most hospitals. During times of seasonal diseases and pandemics, ICUs face high admission demand. In… More >

  • Open Access

    ARTICLE

    Classification of Electrocardiogram Signals for Arrhythmia Detection Using Convolutional Neural Network

    Muhammad Aleem Raza1, Muhammad Anwar2, Kashif Nisar3, Ag. Asri Ag. Ibrahim3,*, Usman Ahmed Raza1, Sadiq Ali Khan4, Fahad Ahmad5

    CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 3817-3834, 2023, DOI:10.32604/cmc.2023.032275

    Abstract With the help of computer-aided diagnostic systems, cardiovascular diseases can be identified timely manner to minimize the mortality rate of patients suffering from cardiac disease. However, the early diagnosis of cardiac arrhythmia is one of the most challenging tasks. The manual analysis of electrocardiogram (ECG) data with the help of the Holter monitor is challenging. Currently, the Convolutional Neural Network (CNN) is receiving considerable attention from researchers for automatically identifying ECG signals. This paper proposes a 9-layer-based CNN model to classify the ECG signals into five primary categories according to the American National Standards Institute (ANSI) standards and the Association… More >

  • Open Access

    ARTICLE

    Identification of EML4 as a key hub gene for endometriosis and its molecular mechanism and potential drug prediction based on the GEO database

    XIANBAO FANG1,#, MINGYAN TANG1,#, ZIYANG YU1,#, JIAQI DING1, CHONG CUI2, HONG ZHANG1,*

    BIOCELL, Vol.47, No.9, pp. 2059-2068, 2023, DOI:10.32604/biocell.2023.030565

    Abstract Objective: Key genes were screened to analyze molecular mechanisms and their drug targets of endometriosis by applying a bioinformatics approach. Methods: Gene expression profiles of endometriosis and healthy controls were obtained from the Gene Expression Omnibus database. Significant differentially expressed genes were screened using the limma package. Correlation pathways were screened by Spearman correlation analysis on the echinoderm microtubule-associated protein-like 4 (EML4) and enrichment in endometriosis pathways and estimated by the GSVA package. Immune characteristics were assessed by the “ESTIMATE” R package. Potential regulatory pathways were determined by enrichment analysis. The SWISS-MODE website was used in homology modeling with EML4… More > Graphic Abstract

    Identification of EML4 as a key hub gene for endometriosis and its molecular mechanism and potential drug prediction based on the GEO database

  • Open Access

    ARTICLE

    An IoT-Based Aquaculture Monitoring System Using Firebase

    Wen-Tsai Sung1, Indra Griha Tofik Isa1,2, Sung-Jung Hsiao3,*

    CMC-Computers, Materials & Continua, Vol.76, No.2, pp. 2179-2200, 2023, DOI:10.32604/cmc.2023.041022

    Abstract Indonesia is a producer in the fisheries sector, with production reaching 14.8 million tons in 2022. The production potential of the fisheries sector can be optimally optimized through aquaculture management. One of the most important issues in aquaculture management is how to efficiently control the fish pond water conditions. IoT technology can be applied to support a fish pond aquaculture monitoring system, especially for catfish species (Siluriformes), in real-time and remotely. One of the technologies that can provide this convenience is the IoT. The problem of this study is how to integrate IoT devices with Firebase’s cloud data system to… More >

  • Open Access

    ARTICLE

    Real-Time Memory Data Optimization Mechanism of Edge IoT Agent

    Shen Guo*, Wanxing Sheng, Shuaitao Bai, Jichuan Zhang, Peng Wang

    Intelligent Automation & Soft Computing, Vol.37, No.1, pp. 799-814, 2023, DOI:10.32604/iasc.2023.038330

    Abstract With the full development of disk-resident databases (DRDB) in recent years, it is widely used in business and transactional applications. In long-term use, some problems of disk databases are gradually exposed. For applications with high real-time requirements, the performance of using disk database is not satisfactory. In the context of the booming development of the Internet of things, domestic real-time databases have also gradually developed. Still, most of them only support the storage, processing, and analysis of data values with fewer data types, which can not fully meet the current industrial process control system data types, complex sources, fast update… More >

  • Open Access

    ARTICLE

    Baseline Isolated Printed Text Image Database for Pashto Script Recognition

    Arfa Siddiqu, Abdul Basit*, Waheed Noor, Muhammad Asfandyar Khan, M. Saeed H. Kakar, Azam Khan

    Intelligent Automation & Soft Computing, Vol.37, No.1, pp. 875-885, 2023, DOI:10.32604/iasc.2023.036426

    Abstract The optical character recognition for the right to left and cursive languages such as Arabic is challenging and received little attention from researchers in the past compared to the other Latin languages. Moreover, the absence of a standard publicly available dataset for several low-resource languages, including the Pashto language remained a hurdle in the advancement of language processing. Realizing that, a clean dataset is the fundamental and core requirement of character recognition, this research begins with dataset generation and aims at a system capable of complete language understanding. Keeping in view the complete and full autonomous recognition of the cursive… More >

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