HANY M. ABD EL-LATEEF1,2,*, SAFA H. QAHL3, EMAN FAYAD4, SARAH A. ALTALHI4, IBRAHIM JAFRI4, EL SHAIMAA SHABANA5, MARWA K. DARWISH6,7, REHAB MAHER8, SAAD SHAABAN1,9, SHADY G. EL-SAWAH10,*
BIOCELL, Vol.47, No.8, pp. 1885-1895, 2023, DOI:10.32604/biocell.2023.030680
- 28 August 2023
Abstract Background: The increasing occurrence of diabetes mellitus (DM) noted worldwide has considerably elicited concern in the recent past. DM is associated with elevated vascular complications, morbidity, mortality, and poor quality of life. In this context, mesenchymal stem cells (MSCs) have shown significant therapeutic potentialities in managing and curing type 1 DM owing to their self-renewable, immunosuppressive, and differentiation capacities. We investigated the potential action of N, N′-diphenyl-1,4-phenylenediamine (DPPD), a well-known synthetic antioxidant to enhance the therapeutic ability of the adipose-derived stem cells (AD-MSCs) in alleviating kidney and liver complications in diabetic rats. Methods: Over the… More >
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