Ji-Su Park¹, Tae-Hyeon Lee², Il-Su Park^3,*

International Journal of Mental Health Promotion, Vol.26, No.9, pp. 745-755, 2024, DOI:10.32604/ijmhp.2024.054630

Abstract Background: In response to the need for research clearly demonstrating the net effect of smoking cessation on mental health status, considering the causal relationship between smoking cessation and changes in mental health status, this study was undertaken. Thus, this study aimed to examine the net effect of short-term smoking cessation on five specific mental health metrics and the overall mental health status score. Methods: We used data from the first wave of the Korean Health Panel (KHP) Survey (2011–2013, 2016–2018) and focused on men aged 19 years and older, to explore the effects of smoking… More >

KERAN JIA¹, YANHAO ZHANG¹, MENGYU JIANG², MENGGE CUI², JIA WANG², JIAJIA ZHANG², HUIHAI ZHAO², MENGYAN LI², HUA WANG², QUANMING ZOU^1,#,*, HAO ZENG^1,#,*

BIOCELL, Vol.48, No.9, pp. 1355-1368, 2024, DOI:10.32604/biocell.2024.051383

Abstract Objective: Candida albicans is a common fungal pathogen that triggers complex host defense mechanisms, including coordinated innate and adaptive immune responses, to neutralize invading fungi effectively. Exploring the immune microenvironment has the potential to inform the development of therapeutic strategies for fungal infections. Methods: The study analyzed individual immune cell profiles in peripheral blood mononuclear cells from Candida albicans-infected mice and healthy control mice using single-cell transcriptomics, fluorescence quantitative PCR, and Western blotting. We investigated intergroup differences in the dynamics of immune cell subpopulation infiltration, pathway enrichment, and differentiation during Candida albicans infection. Results: Our findings indicate that infiltration… More >

Iuon-Chang Lin¹, I-Ling Yeh¹, Ching-Chun Chang², Jui-Chuan Liu³, Chin-Chen Chang^3,*

CMES-Computer Modeling in Engineering & Sciences, Vol.141, No.1, pp. 809-822, 2024, DOI:10.32604/cmes.2024.051612

Abstract Centralized storage and identity identification methods pose many risks, including hacker attacks, data misuse, and single points of failure. Additionally, existing centralized identity management methods face interoperability issues and rely on a single identity provider, leaving users without control over their identities. Therefore, this paper proposes a mechanism for identity identification and data sharing based on decentralized identifiers. The scheme utilizes blockchain technology to store the identifiers and data hashed on the chain to ensure permanent identity recognition and data integrity. Data is stored on InterPlanetary File System (IPFS) to avoid the risk of single More >

Pengcheng Li^1,2,#, Tianze Zhu^1,#, Yunyun Wang^1,2, Shuangyi Yin¹, Xinjie Zhu¹, Minggang Ji¹, Wenye Rui¹, Houmiao Wang¹, Zefeng Yang^1,2,*, Chenwu Xu^1,2,*

Phyton-International Journal of Experimental Botany, Vol.93, No.7, pp. 1441-1453, 2024, DOI:10.32604/phyton.2024.052219

Abstract The nutritional composition and overall quality of maize kernels are largely determined by the key chemical components: protein, oil, and starch. Nevertheless, the genetic basis underlying these nutritional quality traits during grain filling remains poorly understood. In this study, the concentrations of protein, oil, and starch were studied in 204 recombinant inbred lines resulting from a cross between DH1M and T877 at four different stages post-pollination. All the traits exhibited considerable phenotypic variation. During the grain-filling stage, the levels of protein and starch content generally increased, whereas oil content decreased, with significant changes observed between… More >

YUE ZHANG^1,#, WENYU YANG^1,#, XIAOWANG HAN^1,#, YUE QIAO¹, HAITAO WANG², TING CHEN¹, TIANYING LI¹, WEN-BIN OU^1,*

Oncology Research, Vol.32, No.6, pp. 1119-1128, 2024, DOI:10.32604/or.2024.045025

Abstract It has been shown that the high expression of human epididymis protein 4 (HE4) in most lung cancers is related to the poor prognosis of patients, but the mechanism of pathological transformation of HE4 in lung cancer is still unclear. The current study is expected to clarify the function and mechanism of HE4 in the occurrence and metastasis of lung adenocarcinoma (LUAD). Immunoblotting evaluated HE4 expression in lung cancer cell lines and biopsies, and through analysis of The Cancer Genome Atlas (TCGA) dataset. Frequent HE4 overexpression was demonstrated in LUAD, but not in lung squamous… More >

JINNI MA^#, MEILIN ZHOU^#, XIN XU, XINYAO GAO, HAIXIA WANG, JINHUA SHEN, LU XUE^*

BIOCELL, Vol.48, No.2, pp. 239-252, 2024, DOI:10.32604/biocell.2023.045076

Abstract Background: Placenta specific 8 (PLAC8) is a candidate oncogene involved in the development and progression of solid tumors. However, the status of PLAC8 in lung cancer (LC), especially non-small cell lung cancer (NSCLC) is still not lucid. Methods: Tissue microarray analysis (TMA) was performed to detect the expression patterns of PLAC8 in LC tissues and cell lines. Then a series of cellular experiments were performed fto assess cell proliferation, cell cycle profiles, and cell motility to explore the role of PLAC8 in NSCLC-derived cell lines: H1299 and A549. Results: TMA results showed that PLAC8 played complex More >

ANWAR ALI^1,#, SREEKANTH REDDY OBIREDDY^2,#, WING-FU LAI^3,*

BIOCELL, Vol.48, No.2, pp. 163-171, 2024, DOI:10.32604/biocell.2023.043839

Abstract Farnesol is a C15 isoprenyl alcohol generated from the hydrolysis of farnesyl diphosphate under the action of farnesol synthase in plants. Although this sesquiterpenoid alcohol has been exploited in a wide variety of industrial applications, serious discussions on the possible use of this agent in disease treatment have been scant until now. In this article, we review the current understanding of the physiological properties of farnesol and the potential use of the agent as a candidate for treatment development. In fact, since the turn of the last century, farnesol has been found not only to More >

Trong-The Nguyen^1,2,3, Thi-Kien Dao^1,2,3,*, Trinh-Dong Nguyen^2,3

Intelligent Automation & Soft Computing, Vol.37, No.3, pp. 3213-3234, 2023, DOI:10.32604/iasc.2023.041356

Abstract Wireless sensor networks (WSNs) are widely used for various practical applications due to their simplicity and versatility. The quality of service in WSNs is greatly influenced by the coverage, which directly affects the monitoring capacity of the target region. However, low WSN coverage and uneven distribution of nodes in random deployments pose significant challenges. This study proposes an optimal node planning strategy for network coverage based on an adjusted single candidate optimizer (ASCO) to address these issues. The single candidate optimizer (SCO) is a metaheuristic algorithm with stable implementation procedures. However, it has limitations in More >

Qixian Zhang^#, Yi Guo^#, Huicong Liu, Weiping Li, Liqun Zhu, Haining Chen^*

Journal of Renewable Materials, Vol.11, No.8, pp. 3193-3201, 2023, DOI:10.32604/jrm.2023.027730

Abstract All-inorganic CsPbI₃ perovskite has attracted wide attention due to its desirable optical bandgap (E_g: ∼1.7 eV) as well as high chemical stability. Nevertheless, the photovoltaic performance of CsPbI₃ perovskite solar cells (PSCs) was limited by severe nonradiative charge recombination due to high defect density at the grain boundary and surface of perovskite films. To address this issue, a pyrrolidinium iodide (PyI) molecule was introduced to modify the surface and grain boundary of CsPbI₃ perovskite films to passivate defects, which improves the quality of CsPbI₃ perovskite films as well as induces the generation of a quasi-2D Py₂CsPb₂I₇ capping layer… More > Graphic Abstract

QIAN CHEN^1,#, XIN LEI^1,#, GUANHUA HU^1,#, YAN WANG², ZHENGQING FANG¹, GUOQUAN WANG¹, HANG SONG¹, SHU YE^1,*, BIAO CAI^1,*

BIOCELL, Vol.47, No.6, pp. 1265-1277, 2023, DOI:10.32604/biocell.2023.028811

Abstract Background: Huang-Pu-Tong-Qiao formula (HPTQ), a traditional Chinese herbal formula, has a variety of pharmacological effects. It has been used to treat Alzheimer’s disease (AD) for decades. This study aimed to screen differentially expressed proteins in the hippocampus of AD model rats treated with HPTQ. Proteomic studies of the effects of HPTQ on AD are key to understanding the therapeutic mechanisms of HPTQ and identifying potential therapeutic targets. Methods: We hence used the isobaric tags for relative and absolute quantification (ITRAQ) approach to investigate the differentially expressed proteins in the hippocampus of AD model rats before and… More >