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  • Open Access

    ARTICLE

    Levels of evidence and grades of recommendation supporting European society for medical oncology clinical practice guidelines

    MARKO SKELIN1,2,3,*, BRUNA PERKOV-STIPIČIN1, SANJA VUŠKOVIĆ4, MARINA ŠANDRK PLEHAČEK5, ANE BAŠIĆ6, DAVID ŠARČEVIĆ7, MAJA ILIĆ8, IVAN KREČAK2,3,9

    Oncology Research, Vol.32, No.5, pp. 807-815, 2024, DOI:10.32604/or.2024.048948

    Abstract Background: The European Society for Medical Oncology (ESMO) guidelines are among the most comprehensive and widely used clinical practice guidelines (CPGs) globally. However, the level of scientific evidence supporting ESMO CPG recommendations has not been systematically investigated. This study assessed ESMO CPG levels of evidence (LOE) and grades of recommendations (GOR), as well as their trends over time across various cancer settings. Methods: We manually extracted every recommendation with the Infectious Diseases Society of America (IDSA) classification from each CPG. We examined the distribution of LOE and GOR in all available ESMO CPG guidelines across different topics and cancer types.… More >

  • Open Access

    ARTICLE

    A Deep Learning Model for Insurance Claims Predictions

    Umar Isa Abdulkadir*, Anil Fernando*

    Journal on Artificial Intelligence, Vol.6, pp. 71-83, 2024, DOI:10.32604/jai.2024.045332

    Abstract One of the significant issues the insurance industry faces is its ability to predict future claims related to individual policyholders. As risk varies from one policyholder to another, the industry has faced the challenge of using various risk factors to accurately predict the likelihood of claims by policyholders using historical data. Traditional machine-learning models that use neural networks are recognized as exceptional algorithms with predictive capabilities. This study aims to develop a deep learning model using sequential deep regression techniques for insurance claim prediction using historical data obtained from Kaggle with 1339 cases and eight variables. This study adopted a… More >

  • Open Access

    ARTICLE

    A Fault-Tolerant Mobility-Aware Caching Method in Edge Computing

    Yong Ma1, Han Zhao2, Kunyin Guo3,*, Yunni Xia3,*, Xu Wang4, Xianhua Niu5, Dongge Zhu6, Yumin Dong7

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 907-927, 2024, DOI:10.32604/cmes.2024.048759

    Abstract Mobile Edge Computing (MEC) is a technology designed for the on-demand provisioning of computing and storage services, strategically positioned close to users. In the MEC environment, frequently accessed content can be deployed and cached on edge servers to optimize the efficiency of content delivery, ultimately enhancing the quality of the user experience. However, due to the typical placement of edge devices and nodes at the network’s periphery, these components may face various potential fault tolerance challenges, including network instability, device failures, and resource constraints. Considering the dynamic nature of MEC, making high-quality content caching decisions for real-time mobile applications, especially… More >

  • Open Access

    ARTICLE

    DCFNet: An Effective Dual-Branch Cross-Attention Fusion Network for Medical Image Segmentation

    Chengzhang Zhu1,2, Renmao Zhang1, Yalong Xiao1,2,*, Beiji Zou1, Xian Chai1, Zhangzheng Yang1, Rong Hu3, Xuanchu Duan4

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 1103-1128, 2024, DOI:10.32604/cmes.2024.048453

    Abstract Automatic segmentation of medical images provides a reliable scientific basis for disease diagnosis and analysis. Notably, most existing methods that combine the strengths of convolutional neural networks (CNNs) and Transformers have made significant progress. However, there are some limitations in the current integration of CNN and Transformer technology in two key aspects. Firstly, most methods either overlook or fail to fully incorporate the complementary nature between local and global features. Secondly, the significance of integrating the multi-scale encoder features from the dual-branch network to enhance the decoding features is often disregarded in methods that combine CNN and Transformer. To address… More >

  • Open Access

    ARTICLE

    Reliable Data Collection Model and Transmission Framework in Large-Scale Wireless Medical Sensor Networks

    Haosong Gou1, Gaoyi Zhang1, Renê Ripardo Calixto2, Senthil Kumar Jagatheesaperumal3, Victor Hugo C. de Albuquerque2,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 1077-1102, 2024, DOI:10.32604/cmes.2024.047806

    Abstract Large-scale wireless sensor networks (WSNs) play a critical role in monitoring dangerous scenarios and responding to medical emergencies. However, the inherent instability and error-prone nature of wireless links present significant challenges, necessitating efficient data collection and reliable transmission services. This paper addresses the limitations of existing data transmission and recovery protocols by proposing a systematic end-to-end design tailored for medical event-driven cluster-based large-scale WSNs. The primary goal is to enhance the reliability of data collection and transmission services, ensuring a comprehensive and practical approach. Our approach focuses on refining the hop-count-based routing scheme to achieve fairness in forwarding reliability. Additionally,… More >

  • Open Access

    ARTICLE

    Predicting Rock Burst in Underground Engineering Leveraging a Novel Metaheuristic-Based LightGBM Model

    Kai Wang1, Biao He2,*, Pijush Samui3, Jian Zhou4

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 229-253, 2024, DOI:10.32604/cmes.2024.047569

    Abstract Rock bursts represent a formidable challenge in underground engineering, posing substantial risks to both infrastructure and human safety. These sudden and violent failures of rock masses are characterized by the rapid release of accumulated stress within the rock, leading to severe seismic events and structural damage. Therefore, the development of reliable prediction models for rock bursts is paramount to mitigating these hazards. This study aims to propose a tree-based model—a Light Gradient Boosting Machine (LightGBM)—to predict the intensity of rock bursts in underground engineering. 322 actual rock burst cases are collected to constitute an exhaustive rock burst dataset, which serves… More >

  • Open Access

    ARTICLE

    Conditional Generative Adversarial Network Enabled Localized Stress Recovery of Periodic Composites

    Chengkan Xu1,2,4, Xiaofei Wang3, Yixuan Li2, Guannan Wang2,*, He Zhang2,4,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 957-974, 2024, DOI:10.32604/cmes.2024.047327

    Abstract Structural damage in heterogeneous materials typically originates from microstructures where stress concentration occurs. Therefore, evaluating the magnitude and location of localized stress distributions within microstructures under external loading is crucial. Repeating unit cells (RUCs) are commonly used to represent microstructural details and homogenize the effective response of composites. This work develops a machine learning-based micromechanics tool to accurately predict the stress distributions of extracted RUCs. The locally exact homogenization theory efficiently generates the microstructural stresses of RUCs with a wide range of parameters, including volume fraction, fiber/matrix property ratio, fiber shapes, and loading direction. Subsequently, the conditional generative adversarial network… More > Graphic Abstract

    Conditional Generative Adversarial Network Enabled Localized Stress Recovery of Periodic Composites

  • Open Access

    ARTICLE

    Uniaxial Compressive Strength Prediction for Rock Material in Deep Mine Using Boosting-Based Machine Learning Methods and Optimization Algorithms

    Junjie Zhao, Diyuan Li*, Jingtai Jiang, Pingkuang Luo

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 275-304, 2024, DOI:10.32604/cmes.2024.046960

    Abstract Traditional laboratory tests for measuring rock uniaxial compressive strength (UCS) are tedious and time-consuming. There is a pressing need for more effective methods to determine rock UCS, especially in deep mining environments under high in-situ stress. Thus, this study aims to develop an advanced model for predicting the UCS of rock material in deep mining environments by combining three boosting-based machine learning methods with four optimization algorithms. For this purpose, the Lead-Zinc mine in Southwest China is considered as the case study. Rock density, P-wave velocity, and point load strength index are used as input variables, and UCS is regarded… More > Graphic Abstract

    Uniaxial Compressive Strength Prediction for Rock Material in Deep Mine Using Boosting-Based Machine Learning Methods and Optimization Algorithms

  • Open Access

    REVIEW

    A perspective review on the biosynthesis of plant-based secondary metabolites and their application as potent drugs

    JHILAM PRAMANIK1,#, AKASH KUMAR2, SARVESH RUSTAGI3,#, MEHAK KATYAL4, SHEETAL THAKUR5, JUTISHNA BORA6, SUMIRA MALIK6,7,*, ANCHAL TREHAN8, NAYAN TALUKDAR9, PETR SLAMA10,*

    BIOCELL, Vol.48, No.4, pp. 541-557, 2024, DOI:10.32604/biocell.2023.029031

    Abstract Many phytochemicals and their derived metabolites produced by plants are extensively employed in commercial goods, pharmaceutical products as well as in the environmental and medical fields. However, these secondary metabolites obtained from plants are in low amounts, and it is difficult to synthesize them at the industrial level. Despite these challenges, they may be utilized for a variety of medicinal products that are either available in the market or are being researched and tested. Secondary metabolites are complex compounds that exhibit chirality. Further, under controlled conditions with elicitors, desired secondary metabolites may be produced from plant cell cultures. This review… More > Graphic Abstract

    A perspective review on the biosynthesis of plant-based secondary metabolites and their application as potent drugs

  • Open Access

    ARTICLE

    Relationships among Sedentary Time, Electronic Product Addiction, and Depression in Adolescents during the COVID-19 Epidemic: A Cross-Lagged Study

    Feng Sheng1,*, Chen Kong2, Chao Li3

    International Journal of Mental Health Promotion, Vol.26, No.3, pp. 221-228, 2024, DOI:10.32604/ijmhp.2024.030209

    Abstract Objective: This study was conducted to explore the relationships among sedentary behavior (SB), electronic product addiction (EPA), and depression (D) in adolescents during the COVID-19 epidemic. Methods: A total of 604 adolescents (including 309 girls and 295 boys aged 12–18) were selected from Qufu City, Shandong Province, China for three rounds of investigation. The model was constructed using AMOS 23.0 software, and cross-lagged analysis was conducted. Results: SB at T1 can significantly positively predict SB and EPA at T2 (p < 0.05). EPA at T1 can significantly positively predict SB and D at T2 (p < 0.05). Physical activity level… More >

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