Yoann Perreux¹, Marie Alexandre Chaix², Anna Kamp³, François-Pierre Mongeon², Magali Pham², Loïc Boussel¹, Roland Henaine¹, Annie Dore², Blandine Mondésert², Sylvie Di-Filippo¹, Paul Khairy², Francis Bessiere^1,*

Congenital Heart Disease, Vol.15, No.6, pp. 473-482, 2020, DOI:10.32604/CHD.2020.013032

Abstract Sudden cardiac death and heart failure are well known long-term complications after atrial switch for D-transposition of the great arteries (D-TGA). Right systemic ventricular dysfunction is common and myocardial ischemia has been implicated as a putative mechanism for sudden death, with coronary anomalies prevalent in 30% of cases. We sought to assess an association between adverse events and coronary anomalies in patients with D-TGA and atrial switch surgery. An observational study was conducted in 3 tertiary centers (Montreal Heart Institute, Canada, Nationwide Children’s hospital, Chicago, USA and Hopital cardiologique Louis Pradel de Lyon, France). Adults with D-TGA and atrial switch… More >

Domenico Sirico¹, Biagio Castaldi^1,*, Giuseppe Tarantini², Giovanni Di Salvo¹

Congenital Heart Disease, Vol.15, No.6, pp. 441-445, 2020, DOI:10.32604/CHD.2020.012863

Abstract Asymptomatic coronary artery obstruction represents a significant diagnostic challenge in patients with Dextro-Transposition of the Great Arteries and history of Arterial Switch Operation. We report the case of a 17-year-old boy with anomalous origin of left circumflex artery from the right coronary artery, who underwent neonatal arterial switch operation and developed silent myocardial ischemia under stress on myocardial scintigraphy. Despite coronary angiogram and intravascular ultrasound showed only intermediate stenosis of the right coronary artery ostium, the physiological analysis, through the employment of pressure wire, demonstrated a severe reduction of coronary fractional flow reserve after pharmacologically induced hyperemia. Thus, the patient… More >