Sunil Kumar Suryawanshi¹, Usha Chouhan², Jyoti Kant Choudhari^2,*

Molecular & Cellular Biomechanics, Vol.19, No.4, pp. 191-208, 2022, DOI:10.32604/mcb.2022.023911

Abstract Cancer is the second biggest cause of death globally, and the use of therapeutic peptides to specifically target and destroy cancer cells has gotten much interest. Cancer peptides or vaccinations are utilized to treat cancer nowadays, apart from chemotherapy, which has significant discomfort, side effects and costly. It is time demanding to identify and predict potential anticancer peptides using computational biology approaches. Thus, 3-D molecular modeling is being used to find possible ACP candidates. In this research, Curcuma longa has predicted peptide sequences were docked on breast cancer receptors and used a molecular docking technique to assess the anticipated peptides’… More >

MARLA DE CERQUEIRA ALVES¹, MONISE OLIVEIRA SANTOS¹, NASSIB BEZERRA BUENO¹, ORLANDO ROBERTO PIMENTEL DE ARAÚJO², MARÍLIA OLIVEIRA FONSECA GOULART^2,3,4, FABIANA ANDRÉA MOURA^1,5,*

BIOCELL, Vol.46, No.9, pp. 2015-2047, 2022, DOI:10.32604/biocell.2022.020407

Abstract

The roots of the vegetal Curcuma due to its high content of polyphenols, has been used successfully in several clinical situations. This review assessed the effect of curcumin/Curcuma longa on symptoms and metabolic changes in inflammatory bowel disease (IBD). A systematic review of animal models and randomized clinical trials (RCTs) was conducted by searching the following electronic databases: PubMed, CENTRAL, LILACS, Science Direct, and ClinicalTrials.gov. From 997 found records, 62 were included. More than 90% of the animal studies reported an improvement in macroscopic, histologic and/or functional activity; 80% identified decreased oxidative and/or inflammatory biomarkers in animals treated with curcumin.… More >

Deng JB¹, CB Ding¹, L Zhang¹, YH Zhou², RW Yang¹

Phyton-International Journal of Experimental Botany, Vol.80, pp. 181-188, 2011, DOI:10.32604/phyton.2011.80.181

Abstract Four isozymes, superoxide dismutase (SOD), polyphenol oxidase (PPO), malate dehydrogenase (MDH) and cytochrome oxidase (COD) were studied for identification of six herbal species (Curcuma L.). All the 37 study specimens produced a total of 168 polymorphism isozyme bands. The genetic distance coefficients (GS) varied from 0.08 to 0.54. The dendrogram, obtained according to the polymorphism isozyme bands by the UPGMA method with the software NTSYS–pc2.1, contributed to improve the resolution of phylogeny. From the dendrogram, it was possible to differentiate between the wild and cultivated specimens of C. longa, and within C. sichuanensis species. More >

Deng JB^1,2*, G Gao³, KS Ahmad⁴, XQ Luo^1,2, FT Zhang^1,2, S Li^1,2, RW Yang⁵

Phyton-International Journal of Experimental Botany, Vol.87, pp. 156-161, 2018, DOI:10.32604/phyton.2018.87.156

Abstract Six mitochondrial (mtDNA) markers, cox2, ccmFn, ccb256, cox3, Nad4L-orf25, and atp4, were combined to assess genetic relationships by using Maximum Likelihood (ML) and Maximum parsimony (MP). This was done among nine Chinese Curcuma herbal species, included two rare species which are difficult to distinguish from their morphological characters. The relationships are very close among the nine species, and the overall distance was 0.018. In this study, the backbone of such nine species was achieved firstly to date, and being divided into two groups with moderate to strong bootstrap support. Both the ML and MP tree were obtained with similarity topologies… More >