Aadarsha Lamichhane¹, Arun Kuttoor Vasudevan¹, Ethan Dean¹, Mostafa Mohammadabadi^1,*, Kevin Ragon¹, Ardeshir Adeli²

Journal of Renewable Materials, Vol.14, No.1, 2026, DOI:10.32604/jrm.2025.02025-0146 - 23 January 2026

Abstract This study explores a novel method for processing cotton stalks—an abundant agricultural byproduct—into long strips that serve as sustainable raw material for engineered bio-based panels. To evaluate the effect of raw material morphology on panel’s performance, two types of cotton stalk-based panels were developed: one using long strips, maintaining fiber continuity, and the other using ground particles, representing conventional processing. A wood strand-based panel made from commercial southern yellow pine strands served as the control. All panels were bonded using phenol-formaldehyde resin and hot-pressed to a target thickness of 12.7 mm and density of 640 kg/m³.… More >

Hang Zhang^1,#, Meng-Yuan Chu^1,#, Guohui Lv¹, You-Jie Li¹, Xuhang Liu², Fei Jiao^1,*, Yun-Fei Yan^1,*

BIOCELL, Vol.50, No.1, 2026, DOI:10.32604/biocell.2025.068322 - 23 January 2026

Abstract Objectives: Non-small cell lung cancer (NSCLC) remains a leading cause of cancer-related mortality, with limited understanding of lncRNA-driven mechanisms in tumor progression. This study aimed to identify differentially expressed lncRNAs in NSCLC tissues and elucidate the functional role of the significantly upregulated RP3-340N1.2 in promoting malignancy. Methods: RNA sequencing was used to screen dysregulated lncRNAs. RP3-340N1.2 was functionally characterized via gain/loss-of-function assays in NSCLC cells, assessing proliferation, migration, and macrophage polarization. Mechanisms of interleukin 6 (IL-6) regulation were explored using cytokine profiling, Actinomycin D assays, and RNA Immunoprecipitation (RIP) assays to study RP3-340N1.2 interactions with… More >

Xinyang Li^1,2,3,#, Luyuan Ma^1,2,3,#, Chuan Shen^1,2,3, Ruolan Gu^1,2,3, Shilong Dong^1,2,3, Mingjie Liu^1,2,3, Ying Xiao^1,2,3, Wenpeng Liu^1,2,3, Yuexia Liu^1,2,3, Caiyan Zhao^1,2,3,*

Oncology Research, Vol.34, No.2, 2026, DOI:10.32604/or.2025.073179 - 19 January 2026

Abstract Background: Hepatocellular carcinoma (HCC) is an aggressive and lethal malignancy. Metabolic reprogramming dynamically remodels the tumor microenvironment (TME) and drives HCC progression. This study investigated the mechanism through which metabolic reprogramming remodels the TME in HCC. Methods: HCC patient transcriptome data were subjected to bioinformatics analysis to identify differentially expressed genes and immune infiltration status. Immunohistochemical analysis was performed to determine the correlation between succinate dehydrogenase complex subunit A (SDHA) expression and M2 macrophage infiltration. SDHA-knockdown or SDHA-overexpressing HCC cells were used for in vitro experiments, including co-culturing, flow cytometry, and enzyme-linked immunosorbent assay. Western blotting… More >

Marco Siringo^1,2,#,*, Michela De Meo^1,#, Alain Jonathan Gelibter³, Chiara Nicolazzo^4,5,§, Paola Gazzaniga^5,§

Oncology Research, Vol.34, No.2, 2026, DOI:10.32604/or.2025.069832 - 19 January 2026

Abstract Objectives: Although immune checkpoint inhibitors (ICIs) and targeted therapies have reshaped treatment non-small cell lung cancer (NSCLC) paradigms, prognosis remains poor for many patients due to delayed diagnosis and resistance mechanisms. Liquid biopsy offers a minimally invasive approach to monitoring tumor evolution. Among circulating biomarkers, circulating tumor cells (CTCs) and cancer-associated macrophage-like cells (CAM-Ls) may provide complementary prognostic insights. The study aimed to evaluate the prognostic role of CTC and CAM-Ls dynamic in metastatic NSCLC patients. Methods: We retrospectively analyzed 77 patients with metastatic NSCLC who underwent CTC and CAM-L evaluation via the CellSearch® system… More >

Shenghui Su, Yu Zeng, Jiaxin Chen, Xieping Dong^*

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.070558 - 30 December 2025

Abstract Background: Recent studies have shown glycerolipid metabolism played an essential role in multiple tumors, however, its function in osteosarcoma is unclear. This study aimed to explore the role of glycerolipid metabolism in osteosarcoma. Methods: We conducted bioinformatics analysis using data from the Therapeutically Applicable Research to Generate Effective Treatments (TARGET) database and single-cell RNA sequencing. Least Absolute Shrinkage and Selection Operator (LASSO) regression was used to identify the Glycerolipid metabolism-related genes associated with the clinical outcome of osteosarcoma. Tumor-associated macrophages (TAMs) and their interactions with immune cells were examined through single-cell analysis and co-culture experiments.… More >

Mintao Xu^1,#, Zichao Jin^1,#, Yangyang Tian¹, Jingcheng Zhang^1,*, Huiqin Ma¹, Yujin Jing¹, Jiangxing Wu², Jing Zhai²

Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 4059-4078, 2025, DOI:10.32604/phyton.2025.074422 - 29 December 2025

Abstract The frequent outbreaks of crop diseases pose a serious threat to global agricultural production and food security. Data-driven forecasting models have emerged as an effective approach to support early warning and management, yet the lack of user-friendly tools for model development remains a major bottleneck. This study presents the Multi-Scenario Crop Disease Forecasting Modeling System (MSDFS), an open-source platform that enables end-to-end model construction-from multi-source data ingestion and feature engineering to training, evaluation, and deployment-across four representative scenarios: static point-based, static grid-based, dynamic point-based, and dynamic grid-based. Unlike conventional frameworks, MSDFS emphasizes modeling flexibility, allowing… More >

A. B. Rzayeva^1,2,*, F. E. Abbdullayeva¹, S. C. Imanova¹, S. H. Aliyeva^1,2, S. N. Yasinova^1,2

Chalcogenide Letters, Vol.22, No.11, pp. 965-970, 2025, DOI:10.15251/CL.2025.2211.965

Abstract Lead indium selenide (PbIn2Se₄) is a promising chalcogenide semiconductor for optoelectronic and energy applications. We report a hydrothermal synthesis route using ethylene glycol under moderate conditions (433– 453 K, 7–12 h), yielding up to 85–87%. The product crystallized into a cotton-like morphology composed of nanoand microparticles. Structural and compositional integrity were confirmed by chemical analysis, thermogravimetric analysis, and transmission electron microscopy. These results demonstrate that hydrothermal synthesis provides an efficient and controllable pathway to high-purity PbIn2Se₄, opening opportunities for its use in advanced functional devices. More >

Nadia Lamsaadi¹, Oumaima Maarouf², Soukaina Lahmaoui², Hamid Msaad², Omar Farssi², Chaima Hamim², Mohamed Tamoudjout², Hafsa Hirt², Habiba Kamal², Majida El Hassni², Cherki Ghoulam^3,4, Ahmed El Moukhtari^5,*, Mohamed Farissi²

Phyton-International Journal of Experimental Botany, Vol.94, No.11, pp. 3585-3610, 2025, DOI:10.32604/phyton.2025.072311 - 01 December 2025

Abstract Abiotic stresses, such as drought, heavy metals, salinity, and extreme temperatures, are among the most common adverse threats that restrict the use of land for agriculture and limit crop growth and productivity. As sessile organisms, plants defend themselves from abiotic stresses by developing various tolerance mechanisms. These mechanisms are governed by several biochemical traits. The biochemical mechanisms are the products of key genes that express under specific conditions. Interestingly, the expression of these genes is regulated by specialized proteins known as transcription factors (TFs). Several TFs, including those from the bZIP, bHLH, MYB, HSF, WRKY,… More >

Qunlu Liu^1,#, Fiza Liaquat^1,2,#, Qiqi Tang¹, Jun Yang^3,4, Shuai Qiu⁵, Amber Malik², Kang Ye^3,4, Kai Gao⁵, Jun Qin^3,4,*

Phyton-International Journal of Experimental Botany, Vol.94, No.11, pp. 3539-3562, 2025, DOI:10.32604/phyton.2025.071989 - 01 December 2025

Abstract Hydrangea macrophylla is a popular ornamental shrub with a lot of economic and aesthetic value. It is known for its different flower shapes (lacecap and mophead) and the way its flowers change color depending on the pH of the soil. Even though it is important for gardening, we still don’t know much about the molecular processes that lead to flower growth. The purpose of this study was to find and study SNP-related genes and transcription factors that are connected to the growth of H. macrophylla flowers. Genome-wide SNP analysis identified 11 SNPs associated with MYB transcription factors… More >

Omojola Awogbemi^1,*, Daramy Vandi Von Kallon¹, Ramesh C. Ray²

Journal of Renewable Materials, Vol.13, No.11, pp. 2191-2233, 2025, DOI:10.32604/jrm.2025.02025-0112 - 24 November 2025

Abstract Increased human and industrial activities have exacerbated the release of toxic materials and acute environmental pollution in recent times. Biochar, a carbon-rich material produced from biomass, is gaining momentum as a versatile material for attaining a sustainable environment. The study reviews the application of functionalized biochar for energy storage, environmental remediation, catalysis, and sustainable agriculture, aiming to achieve a greener future. The deployment of crop residues as a renewable feedstock for biochar, and their properties, compositions, modification, and functionalization techniques are also discussed. Additionally, the avenues for applying functionalized biochar to achieve a greener future,… More > Graphic Abstract