FABIANA ROCHA ARAÚJO¹, BRUNO MACHADO BERTASSOLI², ISABELLA CRISTINA SOUZA FÉLIX¹, DOUGLAS MARINHO ABREU¹, NATáLIA MELO OCARINO¹, AMANDA MARIA SENA REIS³, JUNEO FREITAS SILVA⁴, ROGéRIA SERAKIDES^1,*

BIOCELL, Vol.47, No.2, pp. 423-430, 2023, DOI:10.32604/biocell.2023.023689

Abstract To evaluate the characteristics and synthesis activity of osteoblasts extracted from the calvaria of offspring of rats exposed to maternal hyperthyroidism. Twelve adult Wistar rats were divided into two groups, one control and one treated with daily administration of L-thyroxine by an orogastric tube (50 µg/animal/day) during pregnancy. Three days after delivery and confirmation of the mothers’ hyperthyroidism, the offspring were euthanized for the extraction of osteoblasts from the calvaria. At 7, 14, and 21 days, proliferation activity was assessed using MTT assay, while alkaline phosphatase (ALP) activity was assessed by the BCIP/NBT method. At 21 days, the total area… More >

Dan Wang¹, Lanzheng Bian², Xiaoyan Hao³, Yiming Liu^1,*, Jinyue Xia⁴, Jing Hu⁵

CMC-Computers, Materials & Continua, Vol.72, No.2, pp. 3899-3912, 2022, DOI:10.32604/cmc.2022.026660

Abstract Craniosynostosis is a common congenital craniofacial deformity caused by premature ossification and closure of one or more cranial sutures. Craniosynostosis will not only affect the normal development of the skull, but also may cause a variety of complications, damage the nervous system, and cause long-term effects on the development of physical and mental health. Therefore, it is particularly important to provide new ideas for clinical treatment by studying the rehabilitation methods of craniosynostosis, and to improve the cure rate. To this end, this paper studies the early rehabilitation methods after craniosynostosis surgery and designs a comprehensive early rehabilitation process and… More >