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    How Does Buoyancy-driven Convection Affect Biological Macromolecular Crystallization? An Analysis of Microgravity and Hypergravity Effects by Means of Magnetic Field Gradients

    N.I. Wakayama1, D.C. Yin2, J.W. Qi3

    FDMP-Fluid Dynamics & Materials Processing, Vol.1, No.2, pp. 153-170, 2005, DOI:10.3970/fdmp.2005.001.153

    Abstract The production of crystals of adequate size and high quality is the "bottleneck'' for three-dimensional structure analysis of protein crystals. In this work, in order to shed additional light on the (still controversial) beneficial effect of microgravity on crystal growth, we focus on recent advanced experimental and theoretical research about the effects of buoyancy-driven convection on protein crystallization. In the light of the numerical studies the following major outcomes can be highlighted: (1) when the crystal size exceeds several dozens of µm, buoyancy-driven convection dominates solute transport near the growing crystal and the crystal growth rate becomes larger than that… More >

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