Ying Ye, Yanan Song, Juhua Zhuang, Saifei He, Jing Ni, Wei Xia
Oncology Research, Vol.26, No.9, pp. 1383-1390, 2018, DOI:10.3727/096504018X15188340975709
Abstract Long noncoding RNA CCAL has been reported to promote tumor progression in various human cancers,
including hepatocellular carcinoma, osteosarcoma, and colorectal cancer. However, the role of CCAL in papillary thyroid cancer remains largely unknown. In the present study, we found that the expression of CCAL was
upregulated in papillary thyroid tumor tissues compared to adjacent normal tissues. Moreover, the expression
of CCAL was positively related with papillary thyroid cancer severity and TNM stage and predicated poor
prognosis. Besides, we found that knockdown of CCAL significantly inhibited papillary thyroid cancer cell
proliferation, migration, and invasion in More >
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