XIAODAN SONG1,#, YUQING WANG1,#, XIUMEI CHENG2,3,*, XIAOYUN ZHANG2, DI WANG4, YANQING REN5, XINHUA LI4, XIAOQIAN DI1, SISI XUE2, TIANYUAN LV1
BIOCELL, Vol.48, No.12, pp. 1761-1772, 2024, DOI:10.32604/biocell.2024.057203
- 30 December 2024
Abstract Background: Prior research has established that exposure to low temperatures adversely affects ovarian function, yet the precise mechanisms remain to be elucidated. Methods: Thirty experimental rats, each demonstrating two regular estrous cycles, were assorted randomly into three distinct groups: a control group, a cold exposure group, and a group treated with 4-phenylbutyric acid (4-PBA). To mimic the conditions of cold exposure, rats in the cold exposure and 4-PBA groups were subjected to immersion in ice water for 21 days. After 7 days of exposure to ice water, the 4-PBA group received intraperitoneal injections of a… More >
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