Zhengfeng Lai, Dongmei Lian, Shaoping Zhang, Yudong Ju, Bizhen Lin, Yunfa Yao, Songhai Wu, Jianji Hong, Zhou Li^*

Phyton-International Journal of Experimental Botany, Vol.93, No.6, pp. 1143-1158, 2024, DOI:10.32604/phyton.2024.051207

Abstract The cytokinin oxidase/dehydrogenase (CKX) enzyme is essential for controlling the fluctuating levels of endogenous cytokinin (CK) and has a significant impact on different aspects of plant growth and development. Nonetheless, there is limited knowledge about CKX genes in tomato (Solanum lycopersicum L.). Here we performed genome-wide identification and analysis of nine SlCKX family members in tomatoes using bioinformatics tools. The results revealed that nine SlCKX genes were unevenly distributed on five chromosomes (Chr.1, Chr.4, Chr.8, Chr.10, and Chr.12). The amino acid length, isoelectric points, and molecular weight of the nine SlCKX proteins ranged from 453 to 553, 5.77… More >

Safwan Al-sayed, Xi Wang, Yijiang Peng^*

CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 4169-4195, 2024, DOI:10.32604/cmc.2024.048916

Abstract The mechanical properties and failure mechanism of lightweight aggregate concrete (LWAC) is a hot topic in the engineering field, and the relationship between its microstructure and macroscopic mechanical properties is also a frontier research topic in the academic field. In this study, the image processing technology is used to establish a micro-structure model of lightweight aggregate concrete. Through the information extraction and processing of the section image of actual light aggregate concrete specimens, the mesostructural model of light aggregate concrete with real aggregate characteristics is established. The numerical simulation of uniaxial tensile test, uniaxial compression… More >

Ayda Khadhri¹, Mohamed Mendili¹, Marwa Bannour-Scharinger¹, Eric Masson², Antonio Pizzi^2,*

Journal of Renewable Materials, Vol.12, No.4, pp. 827-842, 2024, DOI:10.32604/jrm.2024.046950

Abstract This study is the first to evaluate the phytochemical content and biological properties of Tunisian T. platyphyllos Scop. A total of 23 compounds of essential oils were identified by gas chromatography-mass spectrometry (GC-MS) analysis of bracts and fruit extracts. The results show that oxygenated monoterpenes were the dominant class of essential oils. The phenolic composition was investigated by matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF). The analysis showed that the chemical profiles of the ethanolic extracts of bracts and fruits are substantially similar. The highest polyphenol content was found in the ethanolic extracts of the fruits (7.65… More > Graphic Abstract

Zhengfan Lyu^1,3, Yulin Li^2,3, Mengmeng Fan^1,3,*, Yan Huang¹, Chenguang Li²

FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.5, pp. 901-913, 2024, DOI:10.32604/fdmp.2023.043512

Abstract Red mud (RM) is a low-activity industrial solid waste, and its utilization as a resource is currently a hot topic. In this study, the micro characteristics of red mud at different calcination temperatures were analyzed using X-ray diffraction and scanning electron microscopy. The performance of calcined red mud was determined through mortar strength tests. Results indicate that high-temperature calcination can change the mineral composition and microstructure of red mud, and increase the surface roughness and specific surface area. At the optimal temperature of 700°C, the addition of calcined red mud still leads to a decrease More > Graphic Abstract

Wenzhang Zhang^*1, Xin Wu^†1, Liang Hu^*, Yuefan Ma^*, Zihan Xiu^*, Bingyu Huang^*, Yun Feng^*, Xudong Tang^*†‡

Oncology Research, Vol.25, No.5, pp. 843-852, 2017, DOI:10.3727/096504016X14813880882288

Abstract The human papillomavirus (HPV) infection may be associated with the development and progression of nonsmall cell lung cancer (NSCLC). However, the role of HPV-16 oncoproteins in the development and progression of NSCLC is not completely clear. Epithelial–mesenchymal transition (EMT), a crucial step for invasion and metastasis, plays a key role in the development and progression of NSCLC. Here we explored the effect of HPV-16 oncoproteins on EMT and the underlying mechanisms. NSCLC cell lines, A549 and NCI-H460, were transiently transfected with the EGFP-N1-HPV-16 E6 or E7 plasmid. Real-time PCR and Western blot analysis were performed… More >

I Wayan Sumardika^*†, Chen Youyi^*, Eisaku Kondo^‡, Yusuke Inoue^§, I Made Winarsa Ruma^*†, Hitoshi Murata^*, Rie Kinoshita^*, Ken-Ichi Yamamoto^*, Shuta Tomida^¶, Kazuhiko Shien^#, Hiroki Sato^#, Akira Yamauchi^**, Junichiro Futami^††, Endy Widya Putranto^‡‡, Toshihiko Hibino^§§, Shinichi Toyooka^¶#¶¶, Masahiro Nishibori^##, Masakiyo Sakaguchi^*

Oncology Research, Vol.26, No.3, pp. 431-444, 2018, DOI:10.3727/096504017X15031557924123

Abstract We previously identified novel S100A8/A9 receptors, extracellular matrix metalloproteinase inducer (EMMPRIN), melanoma cell adhesion molecule (MCAM), activated leukocyte cell adhesion molecule (ALCAM), and neuroplastin (NPTN) β, that are critically involved in S100A8/A9-mediated cancer metastasis and inflammation when expressed at high levels. However, little is known about the presence of any cancerspecific mechanism(s) that modifies these receptors, further inducing upregulation at protein levels without any transcriptional regulation. Expression levels of glycosyltransferase-encoding genes were examined by a PCRbased profiling array followed by confirmation with quantitative real-time PCR. Cell migration and invasion were assessed using a Boyden chamber.… More >

Ilias Kainis^*, Nikolaos Syrigos^*, Alexandra Kopitopoulou^*, Ioannis Gkiozos^*, Effrosyni Filiou^*, Vasiliki Nikolaou^*, Evangelia Papadavid^†

Oncology Research, Vol.26, No.1, pp. 59-69, 2018, DOI:10.3727/096504017X14913452320194

Abstract Systematic treatment of advanced non-small cell lung cancer (NSCLC) includes targeted treatment with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs). The development of skin rash and its intensity have been associated with EGFR TKI’s efficacy. The main purpose of this study was to further investigate the potential value of erlotinib-associated rash as a predictor of prognosis and treatment response in a real-world cohort of patients with advanced NSCLC. The medical records of all NSCLC patients treated with erlotinib at the Oncology Unit of GPP, Sotiria Athens General Hospital between January 1, 2014 and… More >

Yasemin Baskin^*†‡, Gizem Calibasi Kocal^‡§, Betul Bolat Kucukzeybek^¶, Mahdi Akbarpour^#, Nurcin Kayacik^**, Ozgul Sagol^††, Hulya Ellidokuz^†‡‡, Ilhan Oztop^§§

Oncology Research, Vol.24, No.1, pp. 41-53, 2016, DOI:10.3727/096504016X14576297492418

Abstract Most of the gastrointestinal stromal tumors (GISTs) have gain-of-function mutations in the KIT gene, which can be used as a prognostic marker for the biological behavior of tumors, predictive marker for the response of tyrosine kinase inhibitors, and diagnostic marker. Researchers have focused on PDGFRA mutations because of both their prognostic and predictive potential and DOG1 positivity for diagnosis on GISTs. The aim of this study is to investigate the effect DOG1, PDGFRA, and KIT mutations on the prediction of the outcome for GIST management. Polymerase chain reaction was performed for KIT gene exons 9, 11, 13,… More >

Yuping Bian^*, Xiu Wan, Xiaoyu Zhou

Energy Engineering, Vol.121, No.6, pp. 1637-1656, 2024, DOI:10.32604/ee.2024.047678

Abstract To address uncertainty as well as transient stability constraints simultaneously in the preventive control of wind farm systems, a novel three-stage optimization strategy is established in this paper. In the first stage, the probabilistic multi-objective particle swarm optimization based on the point estimate method is employed to cope with the stochastic factors. The transient security region of the system is accurately ensured by the interior point method in the second stage. Finally, the verification of the final optimal objectives and satisfied constraints are enforced in the last stage. Furthermore, the proposed strategy is a general More >

Yulei Chen¹, Zhaojun Chen^1,2, Shichao Wang¹, Yang Hang¹, Jianpeng Guo^1,*

International Journal of Mental Health Promotion, Vol.26, No.4, pp. 303-315, 2024, DOI:10.32604/ijmhp.2024.046863

Abstract Social-Emotional Competency (SEC), regarded as a critical psychological resource for individuals to adapt to social environments, is an effective protective factor for students’ mental health, impacting their future success and well-being. Analyzing the impact of SEC on university students’ mental health can offer valuable insights for nurturing talents with healthy psychological and physical development. Based on data from two large-scale surveys of Chinese university students, this study designed two comprehensive Multiple Mediation Models involving SEC, stress, coping strategies, and stress reaction to explore the pathway of emotion nurturing mentality. Study 1 utilized a parallel mediation model… More >