Xin-sheng Cheng*†, Shi-bo Sun*, Feng Zhong*, Kun He*, Jie Zhou*
Oncology Research, Vol.24, No.4, pp. 239-245, 2016, DOI:10.3727/096504016X14648701448011
Abstract Our aim was to study the expression of human SET domain containing protein 1A (hSETD1A) in hepatocellular
carcinoma patients and its relationship with human hepatocellular carcinoma cell function. A total of 30 patients
with hepatocellular carcinoma were enrolled in this study. The expression of hSETD1A was detected by real-time
polymerase chain reaction (PCR) and Western blotting. The immortalized normal human liver cell line including
SMMC-7721 was subjected to real-time PCR for hSETD1A mRNA. Furthermore, hSETD1A-small hairpin RNA
(shRNA) was used to knock down hSETD1A expression in SMMC-7721 cells. Cell proliferation, cell apoptosis,
and cell migration More >
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