S. DEIVANAYAKI1,*, P. JAYAMURUGAN2, S. ASHOKAN3, V. GOPALA KRISHNAN4, B. YOGESWARI5
Journal of Polymer Materials, Vol.38, No.3-4, pp. 295-307, 2021, DOI:10.32381/JPM.2021.38.3-4.10
Abstract The cholesterol level determination is a significant clinical diagnostic solution for heart and,
thrombosis problems. In this work, we examined a novel non-enzymatic cholesterol biosensor
using cholesterol oxidase (ChOx) enzyme immobilized on TiO2
nanoparticles influenced by
reduced graphene oxide (rGO) - polypyrrole (PPy) (rGO-TiO2
/PPy-GCE) nanocomposite was
developed on a glassy carbon electrode (GCE) and the higher sensing response with lower
detection limits were observed. The electrochemical properties of GCE modified PPy (PPy-GCE) were studied using CV (Cyclic Voltammetry) and DPV (Differential Pulse Voltammetry).
The reported sensor exhibited piecewise linearity in the range of 0.1 µM More >