YE ZHANG1, YANAN LIANG2, YAN WU2, LIWEN SONG2, ZUWANG ZHANG2,*
Oncology Research, Vol.32, No.11, pp. 1747-1763, 2024, DOI:10.32604/or.2024.030945
- 16 October 2024
Abstract Background: Papillary thyroid cancer (PTC) is the most prevalent histological type of differentiated thyroid malignancy. Circular RNAs (circRNAs) have been implicated in the pathogenesis and progression of various cancers. circTIAM1 (hsa_circ_0061406) is a novel circRNA with aberrant expression in PTC. However, its functional roles in PTC progression remain to be investigated. Methods: The expression levels of circTIAM1 in the PTC and the matched para-cancerous tissues were detected by quantitative real-time reverse-transcription PCR (qRT-PCR). The subcellular localization of circTIAM1 was examined by fluorescence in-situ hybridization (FISH). Kaplan-Meier plot was used to analyze the association of clinicopathological features… More >
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