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  • Open Access

    ARTICLE

    Capsaicin exerts anti-benign prostatic hyperplasia effects via inhibiting androgen receptor signaling pathway

    ZICHEN SHAO1,2,#, CHUNG-YI CHEN3,#, XUZHOU CHEN1, HANWU CHEN1, MENGQIAO SU1,2, HUI SUN1,2, YIDAN LI1,2, BINGHUA TU1, ZITONG WANG1, CHI-MING LIU1,*

    BIOCELL, Vol.47, No.6, pp. 1389-1396, 2023, DOI:10.32604/biocell.2023.028222 - 19 May 2023

    Abstract Background: Benign prostatic hyperplasia (BPH) is a common condition in middle-aged and elderly men. Enlargement of the prostate causes lower urinary tract symptoms. Capsaicin is a phytochemical extracted from chili peppers and exerts many pharmacological actions, such as anti-tumor and anti-inflammatory effects. Methods: Our study investigated the effect of capsaicin in vitro and in a mouse model in vivo. A prostatic stromal myofibroblast cell line (WPMY-1) was co-incubated with testosterone (1 µM) and different concentrations of capsaicin (10–100 µM) for 24 and 48 h. Capsaicin (10–100 µM) significantly inhibited testosterone-treated WPMY-1 cell growth at 48 h by MTT… More >

  • Open Access

    ARTICLE

    Biological control of chili pepper root rot (Capsicum annuum L.) by Bacillus thuringiensis

    Mojica-Marín1* V, HA Luna-Olvera2, CF Sandoval-Coronado2, B Pereyra-Alférez2, LH Morales-Ramos2, NA González-Aguilar2, CE Hernández-Luna2, OG Alvarado-Gomez3

    Phyton-International Journal of Experimental Botany, Vol.78, pp. 105-110, 2009, DOI:10.32604/phyton.2009.78.105

    Abstract Wide spreading of pepper blight on new plantations and on different production areas in Mexico, and the difficulty in controlling this disease, makes it compulsory to develop new control measures. It is expected that these measures provide new tools for controlling this disease in the context of integrated management strategies. The aim of this investigation was to evaluate and determine the antagonistic potential of 64 strains of Bacillus thuringiensis against Rhizoctonia solani, Phytophthora capsici and Fusarium oxysporum by dual culture assays. Strains of B. thuringiensis came from the International Collection of Entomopatogenic Bacillus from FCBUANL. Results showed that 16 More >

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