Ziying Zhang^1,*, Chu Li¹, Junwei Zhu¹, Qinghong Wu¹

The International Conference on Computational & Experimental Engineering and Sciences, Vol.31, No.1, pp. 1-1, 2024, DOI:10.32604/icces.2024.010912

Abstract The process of perfusion seeding of cells into a porous scaffold represents a pivotal initial stage in the development of tissue-engineered bones. The rheological behavior of the cell suspension plays a crucial role in influencing the transport and distribution of cells within the scaffold. Currently, there is limited understanding of the non-Newtonian rheology of cell suspensions in complex pores which differs significantly from simple channels or linear shear flow. In this study, we utilize our previously developed mesoscopic model of perfusion cell seeding to investigate the rheological behavior of cell suspensions at the cellular scale. More >

Laura Isabel Arias-Rodríguez¹, Martha Alicia Rodríguez-Mendiola^2,*, Carlos Arias-Castro^2,*, Federico Antonio Gutiérrez Miceli¹, Diana Reséndez Pérez³, María Celina Luján Hidalgo¹, Juan José Villalobos Maldonado¹, Norma Alejandra Mancilla Margalli²

Phyton-International Journal of Experimental Botany, Vol.92, No.10, pp. 2807-2823, 2023, DOI:10.32604/phyton.2023.030396 - 15 September 2023

Abstract In recent years, there has been a growing interest in exploring alternative treatments for bone defects. Bone tissue engineering has turned its attention to plant extracts containing osteogenic flavonoids as potential promoters of bone regeneration. In our study, we specifically investigated the extract of Petroselinum crispum, a plant known for its abundance of osteogenic flavonoids such as apigenin, quercetin, and kaempferol. Our objective was to compare the total flavonoid content (TFC) and their accumulation in different sources. We obtained hydrolyzed aqueous extracts from the leaves of parsley plants (grown for 12 weeks in the field), weekly… More >

Zhenzhen SHI, Jiaxin CAO, Hailong PANG, Lingyun JIA, Kun SUN, Hanqing FENG^*

BIOCELL, Vol.44, No.1, pp. 89-99, 2020, DOI:10.32604/biocell.2020.08059 - 01 March 2020

Abstract Cadmium (Cd) is one of the most widespread and toxic heavy metals to plants. Extracellular ATP (exATP) is thought to be an extracellular effector in regulating the physiological responses of plant cells to environmental stresses. However, the function of exATP in Cd-stressed plant cells is much unknown. The present work showed that treating tobacco (Nicotiana tabacum L. cv. Bright Yellow-2) cell-suspension cultures with exogenous CdCl₂ reduced the cell viability, exATP level, and Mg content. However, the production of reactive oxygen species (ROS), Cd content, and electrolyte leakage of the cells were enhanced by exogenous CdCl₂. When the… More >