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    ARTICLE

    Cathepsin F Knockdown Induces Proliferation and Inhibits Apoptosis in Gastric Cancer Cells

    Ce Ji*, Ying Zhao*, You-Wei Kou*, Hua Shao*, Lin Guo*, Chen-Hui Bao*, Ben-Chun Jiang*, Xin-Ying Chen*, Jing-Wei Dai, Yu-Xin Tong, Ren Yang*, Wei Sun*, Qiang Wang*

    Oncology Research, Vol.26, No.1, pp. 83-93, 2018, DOI:10.3727/096504017X14928634401204

    Abstract Gastric cancer (GC) is one of the most common cancers in the world. The cathepsin F (CTSF) gene has recently been found to participate in the progression of several types of cancer. However, the clinical characteristics and function of CTSF in GC as well as its molecular mechanisms are not clear. Six GC cell lines and 44 paired adjacent noncancerous and GC tissue samples were used to assess CTSF expression by quantitative polymerase chain reaction (qPCR). We used lentivirus-mediated small hairpin RNA (Lenti-shRNA) against CTSF to knock down the expression of CTSF in GC cells.… More >

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