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  • Open Access

    ARTICLE

    Mitigating Carbon Emissions: A Comprehensive Analysis of Transitioning to Hydrogen-Powered Plants in Japan’s Energy Landscape Post-Fukushima

    Nugroho Agung Pambudi1,2,4,*, Andrew Chapman, Alfan Sarifudin1,3, Desita Kamila Ulfa4, Iksan Riva Nanda5

    Energy Engineering, Vol.121, No.5, pp. 1143-1159, 2024, DOI:10.32604/ee.2024.047555

    Abstract One of the impacts of the Fukushima disaster was the shutdown of all nuclear power plants in Japan, reaching zero production in 2015. In response, the country started importing more fossil energy including coal, oil, and natural gas to fill the energy gap. However, this led to a significant increase in carbon emissions, hindering the efforts to reduce its carbon footprint. In the current situation, Japan is actively working to balance its energy requirements with environmental considerations, including the utilization of hydrogen fuel. Therefore, this paper aims to explore the feasibility and implications of using hydrogen power plants as a… More >

  • Open Access

    ARTICLE

    Rolling Decision Model of Thermal Power Retrofit and Generation Expansion Planning Considering Carbon Emissions and Power Balance Risk

    Dong Pan1, Xu Gui1, Jiayin Xu1, Yuming Shen1, Haoran Xu2, Yinghao Ma2,*

    Energy Engineering, Vol.121, No.5, pp. 1309-1328, 2024, DOI:10.32604/ee.2024.046464

    Abstract With the increasing urgency of the carbon emission reduction task, the generation expansion planning process needs to add carbon emission risk constraints, in addition to considering the level of power adequacy. However, methods for quantifying and assessing carbon emissions and operational risks are lacking. It results in excessive carbon emissions and frequent load-shedding on some days, although meeting annual carbon emission reduction targets. First, in response to the above problems, carbon emission and power balance risk assessment indicators and assessment methods, were proposed to quantify electricity abundance and carbon emission risk level of power planning scenarios, considering power supply regulation… More >

  • Open Access

    ARTICLE

    A Deep Learning Framework for Mass-Forming Chronic Pancreatitis and Pancreatic Ductal Adenocarcinoma Classification Based on Magnetic Resonance Imaging

    Luda Chen1, Kuangzhu Bao2, Ying Chen2, Jingang Hao2,*, Jianfeng He1,3,*

    CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 409-427, 2024, DOI:10.32604/cmc.2024.048507

    Abstract Pancreatic diseases, including mass-forming chronic pancreatitis (MFCP) and pancreatic ductal adenocarcinoma (PDAC), present with similar imaging features, leading to diagnostic complexities. Deep Learning (DL) methods have been shown to perform well on diagnostic tasks. Existing DL pancreatic lesion diagnosis studies based on Magnetic Resonance Imaging (MRI) utilize the prior information to guide models to focus on the lesion region. However, over-reliance on prior information may ignore the background information that is helpful for diagnosis. This study verifies the diagnostic significance of the background information using a clinical dataset. Consequently, the Prior Difference Guidance Network (PDGNet) is proposed, merging decoupled lesion… More >

  • Open Access

    REVIEW

    Targeting brain tumors with innovative nanocarriers: bridging the gap through the blood-brain barrier

    KARAN WADHWA1, PAYAL CHAUHAN1, SHOBHIT KUMAR2, RAKESH PAHWA3,*, RAVINDER VERMA4, RAJAT GOYAL5, GOVIND SINGH1, ARCHANA SHARMA6, NEHA RAO3, DEEPAK KAUSHIK1,*

    Oncology Research, Vol.32, No.5, pp. 877-897, 2024, DOI:10.32604/or.2024.047278

    Abstract Background: Glioblastoma multiforme (GBM) is recognized as the most lethal and most highly invasive tumor. The high likelihood of treatment failure arises from the presence of the blood-brain barrier (BBB) and stem cells around GBM, which avert the entry of chemotherapeutic drugs into the tumor mass. Objective: Recently, several researchers have designed novel nanocarrier systems like liposomes, dendrimers, metallic nanoparticles, nanodiamonds, and nanorobot approaches, allowing drugs to infiltrate the BBB more efficiently, opening up innovative avenues to prevail over therapy problems and radiation therapy. Methods: Relevant literature for this manuscript has been collected from a comprehensive and systematic search of… More > Graphic Abstract

    Targeting brain tumors with innovative nanocarriers: bridging the gap through the blood-brain barrier

  • Open Access

    ARTICLE

    Vers une transformation géométrique géocentrique des espaces urbains : la ville vue à partir du ou des centre(s)

    Cyril Enault*

    Revue Internationale de Géomatique, Vol.33, pp. 77-92, 2024, DOI:10.32604/rig.2024.046591

    Abstract La théorie égocentrée est aujourd’hui bien connue des éthologues et des psychologues mais moins diffusée chez les géographes car elle reste encore à l’état de théorie abstraite. Ce papier se propose dans un premier temps de rendre opérationnel cette approche dans le cadre de travaux géographiques à l’échelle de l’individu. Puis, elle envisage d’établir le lien entre l’échelle individu et l’échelle de la ville avec comme objectif de produire des cartes déformées de la ville. More > Graphic Abstract

    Vers une transformation géométrique géocentrique des espaces urbains : la ville vue à partir du ou des centre(s)

  • Open Access

    REVIEW

    Therapeutic and regenerative potential of different sources of mesenchymal stem cells for cardiovascular diseases

    YARA ALZGHOUL, HALA J. BANI ISSA, AHMAD K. SANAJLEH, TAQWA ALABDUH, FATIMAH RABABAH, MAHA AL-SHDAIFAT, EJLAL ABU-EL-RUB*, FATIMAH ALMAHASNEH, RAMADA R. KHASAWNEH, AYMAN ALZU’BI, HUTHAIFA MAGABLEH

    BIOCELL, Vol.48, No.4, pp. 559-569, 2024, DOI:10.32604/biocell.2024.048056

    Abstract Mesenchymal stem cells (MSCs) are ideal candidates for treating many cardiovascular diseases. MSCs can modify the internal cardiac microenvironment to facilitate their immunomodulatory and differentiation abilities, which are essential to restore heart function. MSCs can be easily isolated from different sources, including bone marrow, adipose tissues, umbilical cord, and dental pulp. MSCs from various sources differ in their regenerative and therapeutic abilities for cardiovascular disorders. In this review, we will summarize the therapeutic potential of each MSC source for heart diseases and highlight the possible molecular mechanisms of each source to restore cardiac function. More >

  • Open Access

    ARTICLE

    Identification prognostic features related to sphingolipid metabolism and experimental validation of TRIM47 in hepatocellular carcinoma

    JIAN TANG1, CHENQIANG ZHU1, YUN CHEN1, YUNLONG WU1, MING HE1, YI ZHOU2, MINGHUA XIE2,*

    BIOCELL, Vol.48, No.4, pp. 639-651, 2024, DOI:10.32604/biocell.2024.047562

    Abstract Background: The specific impact of sphingolipid metabolism on developing hepatocellular Carcinoma (HCC) remains unclear. This study aims to explore the relationship between sphingolipid metabolism and HCC prognosis, immune response, and drug sensitivity. Methods: Data were obtained from The Cancer Genome Atlas (TCGA)-Hepatocellular Carcinoma (LIHC) and Gene Expression Omnibus (GEO, GSE14520 datasets). 47 sphingolipid metabolism genes were obtained from the Kyoto Encyclopedia of Genes and Genomes (KEGG) database. After classifying HCC samples using the Non-negative Matrix Factorization (NMF) clustering method, differentially expressed genes were screened. Then, 8 risk genes were obtained by univariate analysis, survival random forest reduction and lasso analysis.… More > Graphic Abstract

    Identification prognostic features related to sphingolipid metabolism and experimental validation of TRIM47 in hepatocellular carcinoma

  • Open Access

    ARTICLE

    miR-30a-5p/PHTF2 axis regulates the tumorigenesis and metastasis of lung adenocarcinoma

    LIJUAN ZHANG1,#, QINGYIN MENG2,#, LI ZHUANG1, QUAN GONG1, XIANDA HUANG3, XUEQIN LI1, SHIJUAN LI1, GUOQIN WANG4, XICAI WANG5,*

    BIOCELL, Vol.48, No.4, pp. 581-590, 2024, DOI:10.32604/biocell.2024.047260

    Abstract Background: Lung adenocarcinoma is a very pervasive histological form of lung cancers, and inhibiting metastasis is crucial for effective treatment. In this investigation, we explored the functional interaction of miR-30a-5p and the putative transcription factor 2 of the homeodomain (PHTF2) in dictating the aggressiveness and metastasis of lung adenocarcinoma. Method: We collected clinical samples to evaluate the expression patterns of miR-30a-5p and PHTF2 in lung adenocarcinoma along with normal tissues. Cellular experiments including cell count kit (CCK)-8 growth assay, apoptosis analysis, migration and invasion examinations were performed to assess the aggressiveness of lung adenocarcinoma cells. Furthermore, we examined tumorigenesis and… More > Graphic Abstract

    miR-30a-5p/PHTF2 axis regulates the tumorigenesis and metastasis of lung adenocarcinoma

  • Open Access

    ARTICLE

    Inhibition of SLC26A4 regulated by electroacupuncture suppresses the progression of myocardial ischemia-reperfusion injury

    FEI KONG1, QIYUAN TIAN2, BINGLIN KUANG3, LILI SHANG4, XIAOXIAO ZHANG5, DONGYANG LI5, YING KONG6,*

    BIOCELL, Vol.48, No.4, pp. 665-675, 2024, DOI:10.32604/biocell.2024.046342

    Abstract Introduction: Myocardial ischemia-reperfusion (IR) injury has received widespread attention due to its damaging effects. Electroacupuncture (EA) pretreatment has preventive effects on myocardial IR injury. SLC26A4 is a Na+ independent anion reverse transporter and has not been reported in myocardial IR injury. Objectives: To find potential genes that may be regulated by EA and explore the role of this gene in myocardial IR injury. Methods: RNA sequencing and bioinformatics analysis were performed to obtain the differentially expressed genes in the myocardial tissue of IR rats with EA pretreatment. Myocardial infarction size was detected by TTC staining. Serum CK, creatinine kinase-myocardial band,… More > Graphic Abstract

    Inhibition of SLC26A4 regulated by electroacupuncture suppresses the progression of myocardial ischemia-reperfusion injury

  • Open Access

    ARTICLE

    Carrageenan Fiber Prepared by a New Process Route of Ba2+ Ion Pre-Crosslinking in the Spinning Solution

    Liting Jia1, Xiao Han1, Cuixia Qiao2, Gang Zhao2, Yanzhi Xia1, Zhixin Xue1,*

    Journal of Renewable Materials, Vol.12, No.3, pp. 427-441, 2024, DOI:10.32604/jrm.2023.044310

    Abstract Ba2+ pre-crosslinked carrageenan fiber (Ba/CAF) was prepared by adding a small amount of Ba2+ to the carrageenan (CA) solution as the spinning solution. Ba/CAF-n/A, Ba/CAF-n/B and Ba/CAF-n/C were prepared with ethanol solution (combine A), high concentration BaCl2 solution (combine B) and low concentration BaCl2 solution (combine C), as coagulation bath and stretch bath, respectively. The combination of coagulation bath and stretch bath suitable for Ba2+ pre-crosslinking wet spinning was screened. The results showed that Ba2+ can induce the birefringence of the CA molecular chain, and the Ba2+ pre-crosslinking effect is the best when the CA mass fraction is 8.0 wt%.… More > Graphic Abstract

    Carrageenan Fiber Prepared by a New Process Route of Ba<sup>2+</sup> Ion Pre-Crosslinking in the Spinning Solution

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