Hussain AlSalman¹, Taha Alfakih², Mabrook Al-Rakhami², Mohammad Mehedi Hassan^2,*, Amerah Alabrah²

CMES-Computer Modeling in Engineering & Sciences, Vol.141, No.3, pp. 2575-2608, 2024, DOI:10.32604/cmes.2024.055011 - 31 October 2024

Abstract Breast cancer diagnosis through mammography is a pivotal application within medical image-based diagnostics, integral for early detection and effective treatment. While deep learning has significantly advanced the analysis of mammographic images, challenges such as low contrast, image noise, and the high dimensionality of features often degrade model performance. Addressing these challenges, our study introduces a novel method integrating Genetic Algorithms (GA) with pre-trained Convolutional Neural Network (CNN) models to enhance feature selection and classification accuracy. Our approach involves a systematic process: first, we employ widely-used CNN architectures (VGG16, VGG19, MobileNet, and DenseNet) to extract a… More >

SUBHAYAN SUR^1,*, DIMPLE DAVRAY², SOUMYA BASU¹, SUPRIYA KHEUR³, JAYANTA KUMAR PAL¹, SHUCHI NAGAR², AVINASH SANAP³, BHIMAPPA M. RUDAGI³, SAMIR GUPTA⁴

Oncology Research, Vol.32, No.10, pp. 1589-1612, 2024, DOI:10.32604/or.2024.052120 - 18 September 2024

Abstract Oral squamous cell carcinoma (OSCC) is one of the most prevalent forms of head and neck squamous cell carcinomas (HNSCC) with a poor overall survival rate (about 50%), particularly in cases of metastasis. RNA-based cancer biomarkers are a relatively advanced concept, and non-coding RNAs currently have shown promising roles in the detection and treatment of various malignancies. This review underlines the function of long non-coding RNAs (lncRNAs) in the OSCC and its subsequent clinical implications. LncRNAs, a class of non-coding RNAs, are larger than 200 nucleotides and resemble mRNA in numerous ways. However, unlike mRNA,… More >

Syeda Shamaila Zareen^1,*, Guangmin Sun^1,*, Mahwish Kundi², Syed Furqan Qadri³, Salman Qadri⁴

CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 1497-1519, 2024, DOI:10.32604/cmc.2024.047418 - 25 April 2024

Abstract Skin cancer diagnosis is difficult due to lesion presentation variability. Conventional methods struggle to manually extract features and capture lesions spatial and temporal variations. This study introduces a deep learning-based Convolutional and Recurrent Neural Network (CNN-RNN) model with a ResNet-50 architecture which used as the feature extractor to enhance skin cancer classification. Leveraging synergistic spatial feature extraction and temporal sequence learning, the model demonstrates robust performance on a dataset of 9000 skin lesion photos from nine cancer types. Using pre-trained ResNet-50 for spatial data extraction and Long Short-Term Memory (LSTM) for temporal dependencies, the model More >

XIAOJIA HUANG^1,#, CAILU SONG^2,#, JINHUI ZHANG², LEWEI ZHU^3,*, HAILIN TANG^2,*

Oncology Research, Vol.32, No.2, pp. 241-249, 2024, DOI:10.32604/or.2023.046582 - 28 December 2023

Abstract Breast cancer has surpassed lung cancer to become the most common malignancy worldwide. The incidence rate and mortality rate of breast cancer continue to rise, which leads to a great burden on public health. Circular RNAs (circRNAs), a new class of noncoding RNAs (ncRNAs), have been recognized as important oncogenes or suppressors in regulating cancer initiation and progression. In breast cancer, circRNAs have significant roles in tumorigenesis, recurrence and multidrug resistance that are mediated by various mechanisms. Therefore, circRNAs may serve as promising targets of therapeutic strategies for breast cancer management. This study reviews the More >

Muhammad Mumtaz Ali, Faiqa Maqsood, Shiqi Liu, Weiyan Hou, Liying Zhang, Zhenfei Wang^*

CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 2699-2714, 2023, DOI:10.32604/cmc.2023.045310 - 26 December 2023

Abstract Breast cancer, particularly Invasive Ductal Carcinoma (IDC), is a primary global health concern predominantly affecting women. Early and precise diagnosis is crucial for effective treatment planning. Several AI-based techniques for IDC-level classification have been proposed in recent years. Processing speed, memory size, and accuracy can still be improved for better performance. Our study presents ECAM, an Enhanced Channel-Wise Attention Mechanism, using deep learning to analyze histopathological images of Breast Invasive Ductal Carcinoma (BIDC). The main objectives of our study are to enhance computational efficiency using a Separable CNN architecture, improve data representation through hierarchical feature… More >

Muhammad Suleman¹, Faizan Ullah¹, Ghadah Aldehim^2,*, Dilawar Shah¹, Mohammad Abrar^1,3, Asma Irshad⁴, Sarra Ayouni²

CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 3533-3549, 2023, DOI:10.32604/cmc.2023.042365 - 26 December 2023

Abstract The early detection of skin cancer, particularly melanoma, presents a substantial risk to human health. This study aims to examine the necessity of implementing efficient early detection systems through the utilization of deep learning techniques. Nevertheless, the existing methods exhibit certain constraints in terms of accessibility, diagnostic precision, data availability, and scalability. To address these obstacles, we put out a lightweight model known as Smart MobiNet, which is derived from MobileNet and incorporates additional distinctive attributes. The model utilizes a multi-scale feature extraction methodology by using various convolutional layers. The ISIC 2019 dataset, sourced from… More >

Jiaji Wang¹, Muhammad Attique Khan², Shuihua Wang^1,3, Yudong Zhang^1,3,*

CMC-Computers, Materials & Continua, Vol.76, No.2, pp. 2201-2216, 2023, DOI:10.32604/cmc.2023.041191 - 30 August 2023

Abstract Breast cancer is a major public health concern that affects women worldwide. It is a leading cause of cancer-related deaths among women, and early detection is crucial for successful treatment. Unfortunately, breast cancer can often go undetected until it has reached advanced stages, making it more difficult to treat. Therefore, there is a pressing need for accurate and efficient diagnostic tools to detect breast cancer at an early stage. The proposed approach utilizes SqueezeNet with fire modules and complex bypass to extract informative features from mammography images. The extracted features are then utilized to train… More >

EFFAT ALEMZADEH¹, LEILA ALLAHQOLI², HAMIDEH DEHGHAN³, AFROOZ MAZIDIMORADI⁴, ALIREZA GHASEMPOUR³, HAMID SALEHINIYA^5,*

Oncology Research, Vol.31, No.5, pp. 667-675, 2023, DOI:10.32604/or.2023.028406 - 21 July 2023

Abstract Liquid biopsy, including both circulating tumor cells and circulating tumor DNA, is becoming more popular as a diagnostic tool in the clinical management of breast cancer. Elevated concentrations of these biomarkers during cancer treatment may be used as markers for cancer progression as well as to understand the mechanisms underlying metastasis and treatment resistance. Thus, these circulating markers serve as tools for cancer assessing and monitoring through a simple, non-invasive blood draw. However, despite several study results currently noting a potential clinical impact of ctDNA mutation tracking, the method is not used clinically in cancer More > Graphic Abstract

Alia Alshehri, Duaa AlSaeed^*

Intelligent Automation & Soft Computing, Vol.37, No.1, pp. 939-970, 2023, DOI:10.32604/iasc.2023.037096 - 29 April 2023

Abstract One of the most prevalent cancers in women is breast cancer. Early and accurate detection can decrease the mortality rate associated with breast cancer. Governments and health organizations emphasize the significance of early breast cancer screening since it is associated to a greater variety of available treatments and a higher chance of survival. Patients have the best chance of obtaining effective treatment when they are diagnosed early. The detection and diagnosis of breast cancer have involved using various image types and imaging modalities. Breast “infrared thermal” imaging is one of the imaging modalities., a screening… More >

Ahmed A. Alsheikhy^1,*, Yahia F. Said¹, Tawfeeq Shawly²

Computer Systems Science and Engineering, Vol.46, No.1, pp. 799-817, 2023, DOI:10.32604/csse.2023.035269 - 20 January 2023

Abstract Lung cancer is the leading cause of cancer-related death around the globe. The treatment and survival rates among lung cancer patients are significantly impacted by early diagnosis. Most diagnostic techniques can identify and classify only one type of lung cancer. It is crucial to close this gap with a system that detects all lung cancer types. This paper proposes an intelligent decision support system for this purpose. This system aims to support the quick and early detection and classification of all lung cancer types and subtypes to improve treatment and save lives. Its algorithm uses… More >