Yifan Lian^*1, Weiming Fan^†1, Yanlin Huang^‡, Hongbo Wang^*, Jialiang Wang^*, Liang Zhou^‡, Xiaojuan Wu^‡, Meihai Deng^†, Yuehua Huang^*‡

Oncology Research, Vol.26, No.5, pp. 691-701, 2018, DOI:10.3727/096504017X15101398724809

Abstract Trophinin-associated protein (TROAP) was a protein first identified to mediate the process of embryo transplantation and later found to be involved in microtubule regulation. However, little is known about the role of TROAP in hepatocellular carcinoma (HCC). In the present study, we reported that both TROAP mRNA and protein expressions were downregulated in human HCC samples as well as cell lines. A high level of TROAP was associated with small tumor size (p<0.05), minor tumor nodules (p<0.01), and mild vein invasion (p<0.05). We further constructed in vitro TROAP depletion and overexpression HCC cell models. TROAP depletion significantly More >

Waraporn Saentaweesuk^*†‡, Norie Araki^‡, Kulthida Vaeteewoottacharn^*†, Atit Silsirivanit^*†‡, Wunchana Seubwai^†§, Chutima Talabnin^¶, Kanha Muisuk^§, Banchob Sripa^†#, Sopit Wongkham^*†, Seiji Okada^**, Chaisiri Wongkham^*†

Oncology Research, Vol.26, No.4, pp. 605-616, 2018, DOI:10.3727/096504017X15009778205068

Abstract Cholangiocarcinoma (CCA) is a highly metastatic tumor, and the majority of patients with CCA have a short survival time because there are no available effective treatments. Hence, a better understanding regarding CCA metastasis may provide an opportunity to improve the strategies for treatment. A comparison study between the highly metastatic cells and their parental cells is an approach to uncover the molecular mechanisms underlying the metastatic process. In the present study, a lung metastatic CCA cell line, KKU-214L5, was established by the in vivo selection of the tail vein-injected mouse model. KKU-214L5 cells possessed mesenchymal… More >

Yanqun Yu^1,*, Wenhao Xu¹, Yahui Huangfu¹, Jinhai Liu^1,2, Bensheng Wang¹, Kai Liu¹

Energy Engineering, Vol.121, No.6, pp. 1521-1533, 2024, DOI:10.32604/ee.2024.047986

Abstract China’s unconventional gas fields have a large number of low-productivity and low-efficiency wells, many of which are located in remote and environmentally harsh mountainous areas. To address the long-term stable production of these gas wells, plunger-lift technology plays an important role. In order to fully understand and accurately grasp the drainage and gas production mechanisms of plunger-lift, a mechanical model of plunger-liquid column uplift in the plunger-lift process was established, focusing on conventional plunger-lift systems and representative wellbore configurations in the Linxing region. The operating casing pressure of the plunger-lift process and the calculation method… More >

Cheng-Kang Guan, James F. Klausner^*, Renwei Mei

Frontiers in Heat and Mass Transfer, Vol.2, No.4, pp. 1-6, 2011, DOI:10.5098/hmt.v2.4.3002

Abstract Pool boiling critical heat flux (CHF) has been measured for pentane, hexane, methanol, FC-72, FC-87, and R113 on a 25.4 mm diameter smooth brass horizontal surface at five different reduced pressures ranging from 0.01to 0.24. The CHF data are compared with various established CHF models as well as the new mechanistic CHF lift-off model recently proposed by the authors. The dependence of CHF on pressure is examined, and it is found that the lift-off model gives a reasonably good prediction of changes in CHF with step changes in the reduced pressure. The R113 and FC-72 More >

J.N. Chung^a,†, Tailian Chen^b, Shalabh C. Maroo^c

Frontiers in Heat and Mass Transfer, Vol.2, No.2, pp. 1-19, 2011, DOI:10.5098/hmt.v2.2.3004

Abstract Recent research progress in the area of nano/micro scale nucleate boiling is reviewed and an up-to-date summary is provided with a focus on the advances of fundamental boiling physics. This review examines nano/micro scale pool boiling experimental and theoretical/numerical work reported in the open literature. On the experimental side, the topics covered are moving contact line, critical heat flux, boiling curve, nucleation, single bubble boiling cycle, bubble coalescence boiling cycle, heater size effect, nanofluid, and nanoscale-structured heater surface. For the theoretical/numerical work, continuum mechanics modeling of the micro-region and molecular dynamics modeling of the nano-region More >

P. K. Das^*, S. Chakraborty, S. Bhaduri

Frontiers in Heat and Mass Transfer, Vol.3, No.1, pp. 1-17, 2012, DOI:10.5098/hmt.v3.1.3008

Abstract A state of the art review of critical heat flux during flow boiling through mini and microchannels has been provided based on the open literature. This review mainly examines three aspects, namely the experimental investigations, the available correlations and the state of prediction using those correlations and finally the proposed physical mechanisms as well as the theoretical models. Before discussing the specific literature on microchannels, a brief overview of critical heat flux for pool and flow boiling is provided. The review has been concluded with a summary of the available information on this topic and More >

Sira Saisorn^a,b, Somchai Wongwises^b,c,∗

Frontiers in Heat and Mass Transfer, Vol.3, No.1, pp. 1-7, 2012, DOI:10.5098/hmt.v3.1.3007

Abstract Two-phase pressure drop during flow boiling has been studied for several decades. Obviously, the publications available on micro-channels are relatively small compared with those for ordinarily sized channels. Although the use of micro-channels yields several advantages, the pressure drop taking p lace in these extremely small channels is higher than that in the ordinarily sized channels because of the increased wall friction. The knowledge of the two-phase pressure drop characteristics in addition to heat transfer phenomena is essential to the design and evaluation of the micro-systems. In this paper, recent research on the flow boiling More >

Sira Saisorn^a,b, Somchai Wongwises^b,c,*

Frontiers in Heat and Mass Transfer, Vol.3, No.1, pp. 1-15, 2012, DOI:10.5098/hmt.v3.1.3006

Abstract A summary of recent research on flow boiling in micro-channels is provided in this article. This review aims to survey and identify new findings arising in this important area, which may contribute to optimum design and process control of high performance miniature devices comprising extremely small channels. Several criteria for defining a micro-channel are presented at first and the recent works on micro-scale flow boiling are subsequently described into two parts including flow visualization and two-phase heat transfer. The results obtained from a number of p revious studies show that the flow behaviours and heat More >

Yunpeng Ren, J. K. Chen^*, Yuwen Zhang

Frontiers in Heat and Mass Transfer, Vol.3, No.2, pp. 1-7, 2012, DOI:10.5098/hmt.v3.2.3001

Abstract Heat transfer in a copper film irradiated by a femtosecond (fs) laser pulse train and by an integrated dual laser beam of a nanosecond pulse with a fspulse train was studied using the semi-classical two-temperature model. The critical point model with three Lorentzian terms was employed to characterize transient optical properties for the laser energy deposition. The effects of pulse number and separation time on the thermal response were investigated. The results showed that with the same total energy in a fs-pulse train, more pulses for shorter separation time, e.g., 1 ps, and fewer pulses More >

Karim Ragui¹, Mengshuai Chen^1,2, Lin Chen^1,2,3,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.27, No.3, pp. 1-2, 2023, DOI:10.32604/icces.2023.010378

Abstract The ambiguous dynamics associated with heat and mass transfer of invading carbon dioxide in sub-critical and supercritical states, as well as the response of pore-scale resident fluids, play a key role in understanding CO₂ capture and storage (CCUS) and the corresponding phase equilibrium mechanisms. To this end, this paper reveals the transport mechanisms of invading supercritical carbon dioxide (sCO₂) in polluted micromodels using a variant of Lattice-Boltzmann Color Fluid model and descriptive experimental data. The breakthrough time is evaluated by characterizing the displacement velocity, the capillary to pressuredifference ratio, and the transient heat and mass diffusion More >