Zhao Xiaoguang*1,2, Liu Meirong†1, Zhang Jingjing‡, Zhang Ruishen§, Zhang Qing¶, Tan Xiaofeng†2
Oncology Research, Vol.25, No.3, pp. 373-380, 2017, DOI:10.3727/096504016X14741486659473
Abstract The long noncoding CPS1 intronic transcript 1 (lncRNA CPS1-IT1) is a recently identified tumor suppressor
in the lncRNA family of proteins. Whether this lncRNA plays any functional role in solid tumors remains
largely unknown. The present study aimed to investigate the role of lncRNA CPS1-IT1 in human lung cancer.
Expression of lncRNA CPS1-IT1 was initially assessed in human lung cancer and in a series of lung cancer cell
lines. The effects of CPS1-IT1 overexpression on cell proliferation, migration, and invasion were examined in
lung cancer cell lines A549 and 95D. It was found that lncRNA… More >
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