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  • Open Access

    ARTICLE

    Increased MAD2L2 expression predicts poor clinical outcome in Colon Adenocarcinoma

    HAOTONG SUN1,2, HEYING WANG1,3, XIN LI1,2, YANJIE HAO1,2, JUN LING1,2, HUAN WANG1,2, FEIMIAO WANG1,2, FANG XU1,2,*

    BIOCELL, Vol.47, No.3, pp. 607-618, 2023, DOI:10.32604/biocell.2023.026445

    Abstract Background: Colon adenocarcinoma (COAD) is the second leading cause of cancer death worldwide thus, identification of COAD biomarkers is critical. Mitotic Arrest Deficient 2 Like 2 (MAD2L2) is a key factor in mammalian DNA damage repair and is highly expressed in many malignant tumors. This is a comprehensive study of MAD2L2 expression, its diagnostic value, prognostic analysis, potential biological function, and impact on the immune system of patients with COAD. Methods: Gene expression, clinical relevance, prognostic analysis, diagnostic value, GO/KEGG cluster analysis, data obtained from TCGA, and bioinformatics statistical analysis were performed using the R package. Immune responses to MAD2L2More >

  • Open Access

    ARTICLE

    Five Different Formulations of the Finite Strain Perfectly Plastic Equations

    Chein-Shan Liu 1,2

    CMES-Computer Modeling in Engineering & Sciences, Vol.17, No.2, pp. 73-94, 2007, DOI:10.3970/cmes.2007.017.073

    Abstract The primary objectives of the present exposition focus on five different types of representations of the plastic equations obtained from an elastic-perfectly plastic model by employing different corotational stress rates. They are (a) an affine nonlinear system with a finite-dimensional Lie algebra, (b) a canonical linear system in the Minkowski space, (c) a non-canonical linear system in the Minkowski space, (d) the Lie-Poisson bracket formulation, and (e) a two-generator and two-bracket formulation. For the affine nonlinear system we prove that the Lie algebra of the vector fields is so(5,1), which has dimensions fifteen, and by the Lie theory the superposition… More >

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