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  • Open Access

    ARTICLE

    Increased MAD2L2 expression predicts poor clinical outcome in Colon Adenocarcinoma

    HAOTONG SUN1,2, HEYING WANG1,3, XIN LI1,2, YANJIE HAO1,2, JUN LING1,2, HUAN WANG1,2, FEIMIAO WANG1,2, FANG XU1,2,*

    BIOCELL, Vol.47, No.3, pp. 607-618, 2023, DOI:10.32604/biocell.2023.026445

    Abstract Background: Colon adenocarcinoma (COAD) is the second leading cause of cancer death worldwide thus, identification of COAD biomarkers is critical. Mitotic Arrest Deficient 2 Like 2 (MAD2L2) is a key factor in mammalian DNA damage repair and is highly expressed in many malignant tumors. This is a comprehensive study of MAD2L2 expression, its diagnostic value, prognostic analysis, potential biological function, and impact on the immune system of patients with COAD. Methods: Gene expression, clinical relevance, prognostic analysis, diagnostic value, GO/KEGG cluster analysis, data obtained from TCGA, and bioinformatics statistical analysis were performed using the R package. Immune… More >

  • Open Access

    ARTICLE

    Five Different Formulations of the Finite Strain Perfectly Plastic Equations

    Chein-Shan Liu 1,2

    CMES-Computer Modeling in Engineering & Sciences, Vol.17, No.2, pp. 73-94, 2007, DOI:10.3970/cmes.2007.017.073

    Abstract The primary objectives of the present exposition focus on five different types of representations of the plastic equations obtained from an elastic-perfectly plastic model by employing different corotational stress rates. They are (a) an affine nonlinear system with a finite-dimensional Lie algebra, (b) a canonical linear system in the Minkowski space, (c) a non-canonical linear system in the Minkowski space, (d) the Lie-Poisson bracket formulation, and (e) a two-generator and two-bracket formulation. For the affine nonlinear system we prove that the Lie algebra of the vector fields is so(5,1), which has dimensions fifteen, and by the… More >

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