Congenital Heart Disease, Vol.20, Suppl.1, pp. 1-49, 2025

Abstract This article has no abstract. More >

Novik Budiwardhana^1,*, Indah Kartika Murni², Eva Miranda Marwali¹, Pribadi Wiranda Busro³, Fildza Intan Rizkia⁴, Muhamad Faza Soelaeman⁴, Yunita Widyastuti⁵

Congenital Heart Disease, Vol.20, No.5, pp. 591-600, 2025, DOI:10.32604/chd.2025.070345 - 30 November 2025

Abstract Background: Low cardiac output syndrome (LCOS) is a frequent and serious complication after pediatric cardiac surgery. Endothelial glycocalyx (EG) degradation, indicated by elevated syndecan-1, contributes to microvascular dysfunction and postoperative instability. The relationship between syndecan-1 dynamics and surgical risk categories remains unclear. Objective: To examine the association between perioperative syndecan-1 levels and clinical outcomes across Risk Adjustment for Congenital Heart Surgery (RACHS-1) categories. Methods: We analyzed 106 children (RACHS-1 categories 2–4) undergoing elective cardiac surgery with cardiopulmonary bypass (CPB). Syndecan-1 was measured at baseline (T0), 4 h (T4), and 72 h (T72). Outcomes included LCOS, vasoactive inotropic… More >

Ya-Yi Chen^1,2, Tzu-Ting Chen³, Ya-Hsuan Chao⁴, Wen-Ho Chuo⁵, Chieh-Shan Wu^6,7, Ruo-Han Tseng^8,*, Chieh-Chen Huang^9,*

BIOCELL, Vol.49, No.9, pp. 1733-1748, 2025, DOI:10.32604/biocell.2025.067011 - 25 September 2025

Abstract Objectives: Professional antigen-presenting cells known as dendritic cells (DCs) assist as a connection between the innate and adaptive components of the immune response. DCs are attractive targets for immunomodulatory drugs because of their crucial function in triggering immunity. This study set out to examine, for the first time, how hibifolin affected mouse bone-marrow derived (BMDCs) dendritic cells, triggered by lipopolysaccharide (LPS) in vitro. Additionally, a mouse model of contact hypersensitivity (CHS) was used to assess its possible therapeutic effects in vivo. Methods: LPS was administered to BMDCs with or without hibifolin. Major Histocompatibility Complex (MHC) class II,… More >

Xinxin Chen¹, Fuxin Li¹, Jingyu Jia¹, Yajing Tian¹, Xin Li^1,2,3,*

Phyton-International Journal of Experimental Botany, Vol.94, No.3, pp. 825-842, 2025, DOI:10.32604/phyton.2025.062015 - 31 March 2025

Abstract In plants, transcription factor (TF) family LATERAL ORGAN BOUNDARIES DOMAIN (LBD) has been identified to be involved in the ripening and senescence processes of fruits. However, the function of LBD in Hylocereus undatus (Haw.) Britton & Rose (H. undatus) has not been reported yet. Through transcriptomic analysis, virus-induced gene silencing (VIGS) technology, and RT-qPCR validation, we investigated the role of the LBD TFs in the senescence of H. undatus. Transcriptomic analysis revealed that HuLBD1 is a key transcription factor of the LBD family regulating H. undatus senescence. After silencing HuLBD1, 5075 differentially expressed genes (DEGs) were identified. GSEA results showed… More >

Heng Zhao¹, Honghua Ma², Hui Liu¹, Xiang Yan¹, Huaqing Yu¹, Yongjun Xiao¹, Xiao Xiao^3,*

FDMP-Fluid Dynamics & Materials Processing, Vol.21, No.1, pp. 87-105, 2025, DOI:10.32604/fdmp.2024.056577 - 24 January 2025

Abstract The behavior of single-phase flow and conjugate heat transfer in micro-channel heat sinks (MCHS) subjected to a uniform heat flux is investigated by means of numerical simulations. Various geometrical configurations are examined, particularly, the combinations of rectangular solid and perforated blocks, used to create a disturbance in the flow. The analysis focuses on several key aspects and related metrics, including the temperature distribution, the mean Fanning friction factor, the pressure drop, the Nusselt number, and the overall heat transfer coefficient across a range of Reynolds numbers (80–870). It is shown that the introduction of such More >

Congenital Heart Disease, Vol.19, Suppl.1, pp. 1-55, 2024

Abstract This article has no abstract. More >

S. Siamala Devi¹, Chandrakala Kuruba², Yunyoung Nam^3,*, Mohamed Abouhawwash^4,5

Intelligent Automation & Soft Computing, Vol.35, No.2, pp. 1873-1887, 2023, DOI:10.32604/iasc.2023.025504 - 19 July 2022

Abstract Wireless sensor networks (WSNs) are projected to have a wide range of applications in the future. The fundamental problem with WSN is that it has a finite lifespan. Clustering a network is a common strategy for increasing the lifetime of WSNs and, as a result, allowing for faster data transmission. The clustering algorithm’s goal is to select the best cluster head (CH). In the existing system, Hybrid grey wolf sunflower optimization algorithm (HGWSFO)and optimal cluster head selection method is used. It does not provide better competence and output in the network. Therefore, the proposed Hybrid… More >

Chitra Paulpandi^*, Murukesh Chinnasamy, Shanker Nagalingam Rajendiran

Computer Systems Science and Engineering, Vol.43, No.3, pp. 1341-1355, 2022, DOI:10.32604/csse.2022.023882 - 09 May 2022

Abstract The current pandemic highlights the significance and impact of air pollution on individuals. When it comes to climate sustainability, air pollution is a major challenge. Because of the distinctive nature, unpredictability, and great changeability in the reality of toxins and particulates, detecting air quality is a puzzling task. Simultaneously, the ability to predict or classify and monitor air quality is becoming increasingly important, particularly in urban areas, due to the well documented negative impact of air pollution on resident’s health and the environment. To better comprehend the current condition of air quality, this research proposes… More >

Mahmood ul Hassan^1,*, Amin Al-Awady¹, Khalid Mahmood², Shahzad Ali³, Ibrahim Algamdi¹, Muhammad Kashif Saeed⁴, Safdar Zaman⁵

CMC-Computers, Materials & Continua, Vol.69, No.3, pp. 3413-3427, 2021, DOI:10.32604/cmc.2021.018544 - 24 August 2021

Abstract Wireless Sensor Networks (WSNs) are an integral part of the Internet of Things (IoT) and are widely used in a plethora of applications. Typically, sensor networks operate in harsh environments where human intervention is often restricted, which makes battery replacement for sensor nodes impractical. Node failure due to battery drainage or harsh environmental conditions poses serious challenges to the connectivity of the network. Without a connectivity restoration mechanism, node failures ultimately lead to a network partition, which affects the basic function of the sensor network. Therefore, the research community actively concentrates on addressing and solving… More >

Yandong Lu^*1, Fangguo Li^*1, Tao Xu^†, Jie Sun^*1

Oncology Research, Vol.23, No.4, pp. 155-163, 2015, DOI:10.3727/096504016X14519157902681

Abstract Chondrosarcoma (CHS) is the second most common malignant bone sarcoma with increased risk of invasion and metastasis. However, the regulatory mechanisms of CHS tumorigenesis remain unknown. Here we investigated the novel role of miR-497 in regulating chondrosarcoma cell growth and cell cycle arrest. RT-PCR analysis showed that the expression of miR-497 is aberrantly downregulated in human chondrosarcoma samples and cells. After transfection with miR-497 mimic or antagomir, the proliferation and apoptosis of JJ012 and OUMS-27 chondrosarcoma cells were determined by CCK-8 assay and flow cytometric analysis, respectively. Results showed that the proliferation capacity of JJ012… More >