Yang Yang, Yuan-song Bai, Qing Wang
Oncology Research, Vol.25, No.4, pp. 605-615, 2017, DOI:10.3727/096504016X14767450526417
Abstract Recently, increasing evidence has shown that CDGSH iron sulfur domain 2 (CISD2) is involved in the initiation and metastasis of several cancers. However, the evidence of its potential role in pancreatic cancer is still
lacking. In our present study, CISD2 was found to be increased in pancreatic cancer samples and multiple
cell lines. Moreover, statistical analysis revealed that a high level of CISD2 was related to advanced clinical
stage, advanced T-stage, positive vascular invasion, positive distant metastasis, and larger tumor size. In addition, multivariate analysis suggests that CISD2 was an independent prognostic factor in pancreatic… More >
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