QIAOLING WU1,2, ZHAOLEI CUI3, HONGMEI XIA1, SHAN JIANG1, JING BAI4, ZHUO SHAO4, YANG SUN1,*
BIOCELL, Vol.47, No.5, pp. 1039-1050, 2023, DOI:10.32604/biocell.2023.027494
- 10 April 2023
Abstract Background: Ovarian cancer (OC) is a leading cause of gynecological cancer-linked deaths worldwide. Exosomal miR-1825 and its target gene C-type lectin domain family 5 member A (CLEC5A) are associated with tumorigenesis in cancers that was further probed. Methods: Exosomal miR-1825 expression in exosomes and its impact on overall survival (OS) prediction were determined using Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) data. Target genes of miR-1825 were searched in five prediction databases and prognostically significant differentially expressed genes were identified. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were carried… More >
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