AMOURA M. ABOU-EL-NAGA1, SHAKER A. MOUSA2, FAYEZ ALTHOBAITI3, EMAN FAYAD3,*, ENGY S. FAHIM1
BIOCELL, Vol.46, No.2, pp. 535-545, 2022, DOI:10.32604/biocell.2022.017739
- 20 October 2021
Abstract Testicular damage is one of the most hazardous effects as it’s associated with azoospermia. Busulfan (Bu) is a highly toxic chemotherapeutic drug that affects testis. Thirty male Swiss albino mice divided into six groups of 5 animals each. Control (oral 0.9% saline daily for 75 days); Mel (20 mg/kg/day orally for 30 days); ZnO NPs (5 mg/kg/day i.p. for 30 days); BU (single i.p. injection of 40 mg/kg and then left for 45 days); BU + Mel (single 40 mg/kg dose of BU and left for 45 days followed by 20 mg/kg/day Mel for 30 More >